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Protagonist Therapeutics

317 hedge funds and large institutions have $8.3B invested in Protagonist Therapeutics in 2026 Q1 according to their latest regulatory filings, with 59 funds opening new positions, 110 increasing their positions, 102 reducing their positions, and 47 closing their positions.

New
Increased
Maintained
Reduced
Closed

225% more call options, than puts

Call options by funds: $36.2M | Put options by funds: $11.1M

34% more capital invested

Capital invested by funds: $6.18B → $8.3B (+$2.12B)

26% more first-time investments, than exits

New positions opened: 59 | Existing positions closed: 47

10.28% more ownership

Funds ownership: 113.13%123.41% (+10%)

1% more funds holding

Funds holding: 313317 (+4)

8% more repeat investments, than reductions

Existing positions increased: 110 | Existing positions reduced: 102

23% less funds holding in top 10

Funds holding in top 10: 1310 (-3)

Holders
317
Holders Change
+4
Holders Change %
+1.28%
% of All Funds
3.9%
Holding in Top 10
10
Holding in Top 10 Change
-3
Holding in Top 10 Change %
-23.08%
% of All Funds
0.12%
New
59
Increased
110
Reduced
102
Closed
47
Calls
$36.2M
Puts
$11.1M
Net Calls
+$25.1M
Net Calls Change
-$55.5M
Name Holding Trade Value Shares
Change
Change in
Stake
Fisher Asset Management
51
Fisher Asset Management
Washington
$18.3M +$9.64M +108,857 +167%
AAA
52
Affinity Asset Advisors
New York
$18.1M
BCM
53
Boxer Capital Management
California
$17.9M
Raymond James Financial
54
Raymond James Financial
Florida
$17.8M -$367K -4,142 -2%
Susquehanna International Group
55
Susquehanna International Group
Pennsylvania
$17.7M +$13.8M +155,814 +1,325%
JP Morgan Chase
56
JP Morgan Chase
New York
$17.3M +$1.57M +17,690 +11%
Lord, Abbett & Co
57
Lord, Abbett & Co
New Jersey
$17.2M +$14.5M +163,459 New
NFT
58
Nan Fung Trinity
Hong Kong
$16.9M -$1.77M -20,000 -11%
DFO
59
Duquesne Family Office
New York
$16.8M
Citigroup
60
Citigroup
New York
$16.7M +$5.65M +63,802 +67%
RhumbLine Advisers
61
RhumbLine Advisers
Massachusetts
$16.6M +$218K +2,463 +2%
Ameriprise
62
Ameriprise
Minnesota
$15.4M -$2.11M -23,828 -14%
Neuberger Berman Group
63
Neuberger Berman Group
New York
$14.9M +$3.8M +42,968 +44%
Franklin Resources
64
Franklin Resources
California
$14.5M +$5.44M +61,429 +80%
KCM
65
Kennedy Capital Management
Missouri
$14.5M -$7.47M -84,345 -38%
Legal & General Group
66
Legal & General Group
United Kingdom
$14.3M -$1.22M -13,797 -9%
N
67
Nuveen
North Carolina
$13.5M +$182K +2,053 +2%
Manulife (Manufacturers Life Insurance)
68
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$13.5M +$1.28M +14,478 +13%
Deutsche Bank
69
Deutsche Bank
Germany
$13.2M +$1.77M +19,991 +19%
PAM
70
Panagora Asset Management
Massachusetts
$12.3M -$777K -8,775 -7%
UBS AM
71
UBS AM
Illinois
$11.3M +$258K +2,909 +3%
Universal-Beteiligungs- und Servicegesellschaft
72
Universal-Beteiligungs- und Servicegesellschaft
Germany
$11.1M -$755K -8,522 -7%
Balyasny Asset Management
73
Balyasny Asset Management
Illinois
$10.7M +$8.97M +101,299 New
OM
74
Opaleye Management
Massachusetts
$10.5M -$443K -5,000 -5%
Swiss National Bank
75
Swiss National Bank
Switzerland
$10.4M +$62K +700 +0.7%