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Protagonist Therapeutics

132 hedge funds and large institutions have $817M invested in Protagonist Therapeutics in 2021 Q3 according to their latest regulatory filings, with 26 funds opening new positions, 58 increasing their positions, 34 reducing their positions, and 31 closing their positions.

New
Increased
Maintained
Reduced
Closed

71% more call options, than puts

Call options by funds: $25.9M | Put options by funds: $15.1M

71% more repeat investments, than reductions

Existing positions increased: 58 | Existing positions reduced: 34

4% less funds holding

Funds holding: 138132 (-6)

4.9% less ownership

Funds ownership: 102.48%97.59% (-4.9%)

16% less first-time investments, than exits

New positions opened: 26 | Existing positions closed: 31

62% less capital invested

Capital invested by funds: $2.15B → $817M (-$1.33B)

80% less funds holding in top 10

Funds holding in top 10: 102 (-8)

Holders
132
Holders Change
-6
Holders Change %
-4.35%
% of All Funds
2.31%
Holding in Top 10
2
Holding in Top 10 Change
-8
Holding in Top 10 Change %
-80%
% of All Funds
0.04%
New
26
Increased
58
Reduced
34
Closed
31
Calls
$25.9M
Puts
$15.1M
Net Calls
+$10.7M
Net Calls Change
+$12M
Name Holding Trade Value Shares
Change
Change in
Stake
OM
26
Opaleye Management
Massachusetts
$5.85M
Charles Schwab
27
Charles Schwab
California
$5.49M +$1.21M +28,454 +10%
Adage Capital Partners
28
Adage Capital Partners
Massachusetts
$5.32M -$10.7M -250,000 -45%
SI
29
Sofinnova Investments
California
$5.28M -$6.45M -151,373 -34%
Susquehanna International Group
30
Susquehanna International Group
Pennsylvania
$4.74M +$10.5M +246,050 +1,153%
SFM
31
Sphera Funds Management
Israel
$4.61M -$1.82M -42,586 -14%
RCAMU
32
Rothschild & Co Asset Management US
Connecticut
$3.85M -$7.28M -170,745 -44%
Two Sigma Advisers
33
Two Sigma Advisers
New York
$2.58M -$4.72M -110,775 -43%
TLCM
34
Twin Lakes Capital Management
California
$2.47M -$177K -4,153 -3%
Federated Hermes
35
Federated Hermes
Pennsylvania
$2.33M +$2.95M +69,267 +112%
Bank of New York Mellon
36
Bank of New York Mellon
New York
$2.32M -$648K -15,197 -10%
Citadel Advisors
37
Citadel Advisors
Florida
$2.1M -$12.1M -284,504 -71%
D.E. Shaw & Co
38
D.E. Shaw & Co
New York
$2.05M -$5.64M -132,322 -53%
KCM
39
Kennedy Capital Management
Missouri
$1.99M +$1.72M +40,318 +56%
CM
40
Caption Management
Oklahoma
$1.95M +$4.69M +110,000 New
JPC
41
Jabodon PT Co
Nevada
$1.61M +$3.86M +90,656 New
SCM
42
Sio Capital Management
New York
$1.59M +$3.84M +90,000 New
Swiss National Bank
43
Swiss National Bank
Switzerland
$1.55M +$25.6K +600 +0.7%
TCM
44
Tekla Capital Management
Massachusetts
$1.53M +$3.68M +86,237 New
CS
45
Candriam SCA
Luxembourg
$1.48M
Russell Investments Group
46
Russell Investments Group
United Kingdom
$1.36M +$980K +22,998 +43%
SAM
47
Silvercrest Asset Management
New York
$1.26M -$2.05M -48,048 -40%
State of Wisconsin Investment Board
48
State of Wisconsin Investment Board
Wisconsin
$1.26M +$409K +9,600 +16%
N
49
Nuveen
North Carolina
$1.26M -$138K -3,239 -2%
UBS Group
50
UBS Group
Switzerland
$1.23M +$2.84M +66,544 +2,491%

PTGX Hedge Fund Activity: Q3 2021 in Review

132 of the 5,712 institutional investors tracked by Wall St. Rank reported a position in Protagonist Therapeutics (PTGX) for Q3 2021, worth a combined $817M — down 62% from $2.15B a quarter earlier.

Sellers outnumbered buyers: 31 funds closed out of PTGX and 26 opened new positions — a net loss of 5 holders — while 34 trimmed existing stakes and 58 added.

The largest buyer was Point72 Asset Management, adding an estimated $138M. The largest seller was Consonance Capital Management, exiting entirely with an estimated $155M sold.

  • 132 institutional investors held Protagonist Therapeutics (PTGX) as of Q3 2021, down from 138 in Q2 2021.
  • Funds reported $817M of Protagonist Therapeutics stock for Q3 2021, down 62% quarter-over-quarter.
  • 26 funds opened new Protagonist Therapeutics positions in Q3 2021 and 31 closed out, a net change of -5 holders.
  • The largest Protagonist Therapeutics buyer in Q3 2021 was Point72 Asset Management, an estimated $138M added.
  • The largest Protagonist Therapeutics seller in Q3 2021 was Consonance Capital Management, an estimated $155M sold.

Based on aggregated 13F filings for Q3 2021.