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Protagonist Therapeutics

317 hedge funds and large institutions have $8.3B invested in Protagonist Therapeutics in 2026 Q1 according to their latest regulatory filings, with 59 funds opening new positions, 110 increasing their positions, 102 reducing their positions, and 47 closing their positions.

New
Increased
Maintained
Reduced
Closed

225% more call options, than puts

Call options by funds: $36.2M | Put options by funds: $11.1M

34% more capital invested

Capital invested by funds: $6.18B → $8.3B (+$2.12B)

26% more first-time investments, than exits

New positions opened: 59 | Existing positions closed: 47

10.28% more ownership

Funds ownership: 113.13%123.41% (+10%)

1% more funds holding

Funds holding: 313317 (+4)

8% more repeat investments, than reductions

Existing positions increased: 110 | Existing positions reduced: 102

23% less funds holding in top 10

Funds holding in top 10: 1310 (-3)

Holders
317
Holders Change
+4
Holders Change %
+1.28%
% of All Funds
3.9%
Holding in Top 10
10
Holding in Top 10 Change
-3
Holding in Top 10 Change %
-23.08%
% of All Funds
0.12%
New
59
Increased
110
Reduced
102
Closed
47
Calls
$36.2M
Puts
$11.1M
Net Calls
+$25.1M
Net Calls Change
-$55.5M
Name Holding Trade Value Shares
Change
Change in
Stake
PCM
326
Pentwater Capital Management
Florida
-$4.37M -50,000 Closed
SC
327
SummitTX Capital
Texas
-$3.69M -42,266 Closed
ACM
328
Aquatic Capital Management
Illinois
-$3.2M -36,615 Closed
Verition Fund Management
329
Verition Fund Management
Connecticut
-$2.34M -26,792 Closed
PHP
330
Parkman Healthcare Partners
Connecticut
-$2.27M -25,973 Closed
DP
331
Diadema Partners
New Jersey
-$1.98M -22,700 Closed
CCIA
332
Campbell & Co Investment Adviser
Maryland
-$1.84M -21,054 Closed
Millennium Management
333
Millennium Management
New York
-$1.52M -17,391 Closed
DekaBank Deutsche Girozentrale
334
DekaBank Deutsche Girozentrale
Germany
-$489K -15,800 Closed
JG
335
Jain Global
New York
-$1.12M -12,850 Closed
FC
336
FORA Capital
Florida
-$788K -9,130 Closed
Renaissance Technologies
337
Renaissance Technologies
New York
-$713K -8,167 Closed
PAP
338
Persistent Asset Partners
Hong Kong
-$691K -7,908 Closed
Tudor Investment Corp
339
Tudor Investment Corp
Connecticut
-$683K -7,718 Closed
HI
340
Horizon Investments
North Carolina
-$652K -7,461 Closed
FRM
341
Fox Run Management
Connecticut
-$581K -6,654 Closed
CG
342
Caprock Group
Idaho
-$523K -5,991 Closed
FCM
343
Fieldview Capital Management
Michigan
-$510K -5,841 Closed
Aviva
344
Aviva
United Kingdom
-$490K -5,609 Closed
Arrowstreet Capital
345
Arrowstreet Capital
Massachusetts
-$443K -5,076 Closed
JFG
346
Jefferies Financial Group
New York
-$437K -5,000 Closed
TCA
347
Taconic Capital Advisors
New York
-$437K -5,000 Closed
CIP
348
Cornerstone Investment Partners
Georgia
-$405K -4,634 Closed
NVCHI
349
New Vernon Capital Holdings II
New Jersey
-$361K -4,137 Closed
Mackenzie Financial
350
Mackenzie Financial
Ontario, Canada
-$318K -3,648 Closed