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ProQR Therapeutics
PRQR

77 hedge funds and large institutions have $118M invested in ProQR Therapeutics in 2024 Q4 according to their latest regulatory filings, with 39 funds opening new positions, 17 increasing their positions, 6 reducing their positions, and 8 closing their positions.

New
Increased
Maintained
Reduced
Closed

388% more first-time investments, than exits

New positions opened: 39 | Existing positions closed: 8

271% more capital invested

Capital invested by funds: $31.7M → $118M (+$86M)

183% more repeat investments, than reductions

Existing positions increased: 17 | Existing positions reduced: 6

82% more call options, than puts

Call options by funds: $296K | Put options by funds: $163K

64% more funds holding

Funds holding: 47 → 77 (+30)

21.69% more ownership

Funds ownership: 21.36% → 43.05% (+22%)

0% more funds holding in top 10

Funds holding in top 10: 2 → 2 (0)

Holders
77
Holders Change
+30
Holders Change %
+63.83%
% of All Funds
1.01%
Holding in Top 10
2
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
0.03%
New
39
Increased
17
Reduced
6
Closed
8
Calls
$296K
Puts
$163K
Net Calls
+$133K
Net Calls Change
-$678K

Top Buyers

Rank Fund Capital Flow
1
Adage Capital Partners
Adage Capital Partners
Massachusetts
+$19M
2
WP
Woodline Partners
California
+$11.3M
3
AAA
Affinity Asset Advisors
New York
+$8.97M
4
Millennium Management
Millennium Management
New York
+$8.52M
5
UBS Group
UBS Group
Switzerland
+$7.33M

Top Sellers

Rank Fund Capital Flow
1
EC
EcoR1 Capital
California
-$3.34M
2
PFM
Privium Fund Management
Netherlands
-$2.05M
3
IC
Ikarian Capital
Texas
-$880K
4
SSA
Schonfeld Strategic Advisors
New York
-$750K
5
Two Sigma Advisers
Two Sigma Advisers
New York
-$185K
Name Holding Trade Value Shares
Change 		Change in
Stake
BP
51
Ballentine Partners
Massachusetts
$61K +$73.1K +23,035 New
VPIM
52
Vanguard Personalized Indexing Management
California
$56.8K – – –
ACM
53
ADAR1 Capital Management
Texas
$54K +$64.8K +20,394 New
Mariner
54
Mariner
Kansas
$48.6K – – –
TSS
55
Two Sigma Securities
New York
$40.1K +$48K +15,116 New
EGM
56
Engineers Gate Manager
New York
$38.6K +$46.3K +14,580 New
AI
57
Atom Investors
Texas
$34.7K – – –
Invesco
58
Invesco
Georgia
$31.5K +$37.7K +11,887 New
Jane Street
59
Jane Street
New York
$30.2K +$36.2K +11,400 New
KAS
60
Kestra Advisory Services
Texas
$26.5K – – –
Truist Financial
61
Truist Financial
North Carolina
$26.5K – – –
Simplex Trading
62
Simplex Trading
Illinois
$26K +$31.5K +9,909 New
Wells Fargo
63
Wells Fargo
California
$23.2K -$1.5K -471 -5%
Osaic Holdings
64
Osaic Holdings
Arizona
$19.2K – – –
S
65
SignatureFD
Georgia
$15.4K +$18.5K +5,824 New
QCG
66
Quadrant Capital Group
Ohio
$14.5K +$17.4K +5,488 New
TRCT
67
Tower Research Capital (TRC)
New York
$9.63K +$11.5K +3,632 New
US Bancorp
68
US Bancorp
Minnesota
$5.87K +$7.03K +2,214 New
LC
69
Lindbrook Capital
California
$5.66K +$6.78K +2,135 New
PP
70
PFS Partners
New Jersey
$2.65K – – –
SPIA
71
Steward Partners Investment Advisory
New York
$1.73K +$2.07K +651 New
CWP
72
Concord Wealth Partners
Virginia
$1.18K +$1.41K +444 New
Royal Bank of Canada
73
Royal Bank of Canada
Ontario, Canada
$1K – – –
SS
74
SBI Securities
Japan
$260 +$311 +98 New
TWC
75
TD Waterhouse Canada
Ontario, Canada
$106 – – –
1 2
3
4

PRQR Hedge Fund Activity: Q4 2024 in Review

77 of the 7,592 institutional investors tracked by Wall St. Rank reported a position in ProQR Therapeutics (PRQR) for Q4 2024, worth a combined $118M — up 271% from $31.7M a quarter earlier.

Buyers outnumbered sellers: 39 funds opened new PRQR positions and 8 closed out — a net gain of 31 holders — while 17 added to existing stakes and 6 trimmed.

The largest buyer was Adage Capital Partners, adding an estimated $19M. The largest seller was EcoR1 Capital, exiting entirely with an estimated $3.34M sold.

  • 77 institutional investors held ProQR Therapeutics (PRQR) as of Q4 2024, up from 47 in Q3 2024.
  • Funds reported $118M of ProQR Therapeutics stock for Q4 2024, up 271% quarter-over-quarter.
  • 39 funds opened new ProQR Therapeutics positions in Q4 2024 and 8 closed out, a net change of +31 holders.
  • The largest ProQR Therapeutics buyer in Q4 2024 was Adage Capital Partners, an estimated $19M added.
  • The largest ProQR Therapeutics seller in Q4 2024 was EcoR1 Capital, an estimated $3.34M sold.

Based on aggregated 13F filings for Q4 2024.