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ProQR Therapeutics

65 hedge funds and large institutions have $54.9M invested in ProQR Therapeutics in 2025 Q1 according to their latest regulatory filings, with 7 funds opening new positions, 18 increasing their positions, 19 reducing their positions, and 19 closing their positions.

New
Increased
Maintained
Reduced
Closed

100% more call options, than puts

Call options by funds: $66K | Put options by funds: $33K

5% less repeat investments, than reductions

Existing positions increased: 18 | Existing positions reduced: 19

3.8% less ownership

Funds ownership: 43.05%39.25% (-3.8%)

16% less funds holding

Funds holding: 7765 (-12)

50% less funds holding in top 10

Funds holding in top 10: 21 (-1)

53% less capital invested

Capital invested by funds: $118M → $54.9M (-$62.8M)

63% less first-time investments, than exits

New positions opened: 7 | Existing positions closed: 19

Holders
65
Holders Change
-12
Holders Change %
-15.58%
% of All Funds
0.87%
Holding in Top 10
1
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-50%
% of All Funds
0.01%
New
7
Increased
18
Reduced
19
Closed
19
Calls
$66K
Puts
$33K
Net Calls
+$33K
Net Calls Change
-$100K
Name Holding Trade Value Shares
Change
Change in
Stake
Adage Capital Partners
1
Adage Capital Partners
Massachusetts
$10.8M -$3.19M -1,500,182 -16%
PFM
2
Privium Fund Management
Netherlands
$6.63M
AAA
3
Affinity Asset Advisors
New York
$4.37M +$978K +459,512 +16%
Millennium Management
4
Millennium Management
New York
$2.75M -$1.61M -756,632 -27%
SCM
5
Sio Capital Management
New York
$2.73M
Aberdeen Group
6
Aberdeen Group
United Kingdom
$2.46M +$3.94M +1,850,348 New
UBS Group
7
UBS Group
Switzerland
$2.38M -$1.11M -523,001 -23%
KCM
8
Kynam Capital Management
New Jersey
$2.33M
DCM
9
DAFNA Capital Management
California
$2.08M
SL
10
Siren LLC
Connecticut
$2.06M -$48.6K -22,817 -1%
PIM
11
Platinum Investment Management
Australia
$2.05M
Morgan Stanley
12
Morgan Stanley
New York
$1.84M +$1.91M +897,508 +185%
WP
13
Woodline Partners
California
$1.76M -$4.75M -2,231,346 -63%
ACH
14
ArrowMark Colorado Holdings
Colorado
$1.66M +$135K +63,625 +5%
MCM
15
M28 Capital Management
Connecticut
$1.36M
Citadel Advisors
16
Citadel Advisors
Florida
$1.09M +$873K +410,051 +100%
Point72 Asset Management
17
Point72 Asset Management
Connecticut
$998K -$1.58M -741,275 -50%
Macquarie Group
18
Macquarie Group
Australia
$825K
Walleye Capital
19
Walleye Capital
New York
$670K +$111K +52,261 +12%
MAM
20
Monaco Asset Management
Monaco
$628K +$373K +175,290 +59%
Northern Trust
21
Northern Trust
Illinois
$521K -$55K -25,857 -6%
Two Sigma Investments
22
Two Sigma Investments
New York
$402K -$173K -81,222 -21%
BFM
23
Boothbay Fund Management
New York
$298K -$76.9K -36,146 -14%
DP
24
Diadema Partners
New Jersey
$276K +$106K +49,671 +31%
FSA
25
Franklin Street Advisors
North Carolina
$200K

PRQR Hedge Fund Activity: Q1 2025 in Review

65 of the 7,457 institutional investors tracked by Wall St. Rank reported a position in ProQR Therapeutics (PRQR) for Q1 2025, worth a combined $54.9M — down 53% from $118M a quarter earlier.

Sellers outnumbered buyers: 19 funds closed out of PRQR and 7 opened new positions — a net loss of 12 holders — while 19 trimmed existing stakes and 18 added.

The largest buyer was Aberdeen Group, opening a new position worth an estimated $3.94M. The largest seller was Woodline Partners, cutting an estimated $4.75M.

  • 65 institutional investors held ProQR Therapeutics (PRQR) as of Q1 2025, down from 77 in Q4 2024.
  • Funds reported $54.9M of ProQR Therapeutics stock for Q1 2025, down 53% quarter-over-quarter.
  • 7 funds opened new ProQR Therapeutics positions in Q1 2025 and 19 closed out, a net change of -12 holders.
  • The largest ProQR Therapeutics buyer in Q1 2025 was Aberdeen Group, an estimated $3.94M added.
  • The largest ProQR Therapeutics seller in Q1 2025 was Woodline Partners, an estimated $4.75M sold.

Based on aggregated 13F filings for Q1 2025.