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ProQR Therapeutics
PRQR

77 hedge funds and large institutions have $118M invested in ProQR Therapeutics in 2024 Q4 according to their latest regulatory filings, with 39 funds opening new positions, 17 increasing their positions, 6 reducing their positions, and 8 closing their positions.

New
Increased
Maintained
Reduced
Closed

388% more first-time investments, than exits

New positions opened: 39 | Existing positions closed: 8

271% more capital invested

Capital invested by funds: $31.7M → $118M (+$86M)

183% more repeat investments, than reductions

Existing positions increased: 17 | Existing positions reduced: 6

82% more call options, than puts

Call options by funds: $296K | Put options by funds: $163K

64% more funds holding

Funds holding: 47 → 77 (+30)

21.69% more ownership

Funds ownership: 21.36% → 43.05% (+22%)

0% more funds holding in top 10

Funds holding in top 10: 2 → 2 (0)

Holders
77
Holders Change
+30
Holders Change %
+63.83%
% of All Funds
1.01%
Holding in Top 10
2
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
0.03%
New
39
Increased
17
Reduced
6
Closed
8
Calls
$296K
Puts
$163K
Net Calls
+$133K
Net Calls Change
-$678K

Top Buyers

Rank Fund Capital Flow
1
Adage Capital Partners
Adage Capital Partners
Massachusetts
+$19M
2
WP
Woodline Partners
California
+$11.3M
3
AAA
Affinity Asset Advisors
New York
+$8.97M
4
Millennium Management
Millennium Management
New York
+$8.52M
5
UBS Group
UBS Group
Switzerland
+$7.33M

Top Sellers

Rank Fund Capital Flow
1
EC
EcoR1 Capital
California
-$3.34M
2
PFM
Privium Fund Management
Netherlands
-$2.05M
3
IC
Ikarian Capital
Texas
-$880K
4
SSA
Schonfeld Strategic Advisors
New York
-$750K
5
Two Sigma Advisers
Two Sigma Advisers
New York
-$185K
Name Holding Trade Value Shares
Change 		Change in
Stake
Adage Capital Partners
1
Adage Capital Partners
Massachusetts
$25.4M +$19M +5,976,813 +165%
PFM
2
Privium Fund Management
Netherlands
$13.2M -$2.05M -646,755 -11%
WP
3
Woodline Partners
California
$9.43M +$11.3M +3,557,001 New
Millennium Management
4
Millennium Management
New York
$7.49M +$8.52M +2,683,351 +1,864%
AAA
5
Affinity Asset Advisors
New York
$7.49M +$8.97M +2,825,000 New
UBS Group
6
UBS Group
Switzerland
$6.12M +$7.33M +2,307,150 +79,557%
SCM
7
Sio Capital Management
New York
$5.44M +$6.52M +2,054,593 New
KCM
8
Kynam Capital Management
New Jersey
$4.64M +$5.56M +1,750,000 New
SL
9
Siren LLC
Connecticut
$4.17M +$5M +1,575,000 New
DCM
10
DAFNA Capital Management
California
$4.15M +$2.1M +661,979 +73%
PIM
11
Platinum Investment Management
Australia
$4.08M +$4.88M +1,538,247 New
Point72 Asset Management
12
Point72 Asset Management
Connecticut
$3.95M +$4.74M +1,491,275 New
ACH
13
ArrowMark Colorado Holdings
Colorado
$3.13M +$3.75M +1,181,413 New
MCM
14
M28 Capital Management
Connecticut
$2.7M – – –
Macquarie Group
15
Macquarie Group
Australia
$1.64M – – –
ACM
16
Altium Capital Management
New York
$1.52M +$1.83M +575,000 New
Morgan Stanley
17
Morgan Stanley
New York
$1.29M +$672K +211,535 +77%
Walleye Capital
18
Walleye Capital
New York
$1.2M +$1.43M +451,303 New
Northern Trust
19
Northern Trust
Illinois
$1.11M +$1.28M +401,648 +2,550%
Citadel Advisors
20
Citadel Advisors
Florida
$1.08M +$1.02M +321,830 +370%
Two Sigma Investments
21
Two Sigma Investments
New York
$1.02M +$1.02M +320,614 +513%
MAM
22
Monaco Asset Management
Monaco
$786K -$99.3K -31,274 -10%
BFM
23
Boothbay Fund Management
New York
$690K +$488K +153,573 +144%
UOC
24
UBS O'Connor
Illinois
$602K +$721K +227,020 New
DP
25
Diadema Partners
New Jersey
$419K +$502K +158,023 New
1
2 3 4

PRQR Hedge Fund Activity: Q4 2024 in Review

77 of the 7,592 institutional investors tracked by Wall St. Rank reported a position in ProQR Therapeutics (PRQR) for Q4 2024, worth a combined $118M — up 271% from $31.7M a quarter earlier.

Buyers outnumbered sellers: 39 funds opened new PRQR positions and 8 closed out — a net gain of 31 holders — while 17 added to existing stakes and 6 trimmed.

The largest buyer was Adage Capital Partners, adding an estimated $19M. The largest seller was EcoR1 Capital, exiting entirely with an estimated $3.34M sold.

  • 77 institutional investors held ProQR Therapeutics (PRQR) as of Q4 2024, up from 47 in Q3 2024.
  • Funds reported $118M of ProQR Therapeutics stock for Q4 2024, up 271% quarter-over-quarter.
  • 39 funds opened new ProQR Therapeutics positions in Q4 2024 and 8 closed out, a net change of +31 holders.
  • The largest ProQR Therapeutics buyer in Q4 2024 was Adage Capital Partners, an estimated $19M added.
  • The largest ProQR Therapeutics seller in Q4 2024 was EcoR1 Capital, an estimated $3.34M sold.

Based on aggregated 13F filings for Q4 2024.