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ProQR Therapeutics

64 hedge funds and large institutions have $80M invested in ProQR Therapeutics in 2025 Q3 according to their latest regulatory filings, with 8 funds opening new positions, 14 increasing their positions, 12 reducing their positions, and 6 closing their positions.

New
Increased
Maintained
Reduced
Closed

33% more first-time investments, than exits

New positions opened: 8 | Existing positions closed: 6

17% more repeat investments, than reductions

Existing positions increased: 14 | Existing positions reduced: 12

3% more funds holding

Funds holding: 6264 (+2)

3% less capital invested

Capital invested by funds: $82.4M → $80M (-$2.41M)

2.77% less ownership

Funds ownership: 38.45%35.68% (-2.8%)

50% less funds holding in top 10

Funds holding in top 10: 21 (-1)

Holders
64
Holders Change
+2
Holders Change %
+3.23%
% of All Funds
0.84%
Holding in Top 10
1
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-50%
% of All Funds
0.01%
New
8
Increased
14
Reduced
12
Closed
6
Calls
$13K
Puts
Net Calls
+$13K
Net Calls Change
-$117K
Name Holding Trade Value Shares
Change
Change in
Stake
Adage Capital Partners
1
Adage Capital Partners
Massachusetts
$13.3M -$761K -348,471 -5%
PFM
2
Privium Fund Management
Netherlands
$10.6M +$1.58K +725 +0%
AAA
3
Affinity Asset Advisors
New York
$7.67M +$220K +100,488 +3%
Morgan Stanley
4
Morgan Stanley
New York
$6.18M -$398K -182,288 -6%
Aberdeen Group
5
Aberdeen Group
United Kingdom
$4.9M +$980K +448,475 +24%
SCM
6
Sio Capital Management
New York
$4.42M
KCM
7
Kynam Capital Management
New Jersey
$3.51M
DCM
8
DAFNA Capital Management
California
$3.34M
SL
9
Siren LLC
Connecticut
$3.31M
ACH
10
ArrowMark Colorado Holdings
Colorado
$2.65M +$102K +46,596 +4%
PIM
11
Platinum Investment Management
Australia
$2.63M -$471K -215,455 -15%
MCM
12
M28 Capital Management
Connecticut
$2.17M
IC
13
Ikarian Capital
Texas
$1.9M +$52.8K +24,160 +3%
Point72 Asset Management
14
Point72 Asset Management
Connecticut
$1.6M
Citadel Advisors
15
Citadel Advisors
Florida
$1.4M +$607K +277,749 +73%
Macquarie Group
16
Macquarie Group
Australia
$1.32M
Walleye Capital
17
Walleye Capital
New York
$1.13M
MAM
18
Monaco Asset Management
Monaco
$980K
Two Sigma Investments
19
Two Sigma Investments
New York
$889K +$422K +193,260 +86%
Northern Trust
20
Northern Trust
Illinois
$628K -$219K -100,037 -25%
BFM
21
Boothbay Fund Management
New York
$529K +$52.8K +24,160 +11%
Millennium Management
22
Millennium Management
New York
$513K -$2.33M -1,066,911 -82%
Two Sigma Advisers
23
Two Sigma Advisers
New York
$487K +$193K +88,300 +63%
PAI
24
Palo Alto Investors
California
$402K +$413K +188,807 New
DP
25
Diadema Partners
New Jersey
$336K

PRQR Hedge Fund Activity: Q3 2025 in Review

64 of the 7,626 institutional investors tracked by Wall St. Rank reported a position in ProQR Therapeutics (PRQR) for Q3 2025, worth a combined $80M — down 2.9% from $82.4M a quarter earlier.

Buyers outnumbered sellers: 8 funds opened new PRQR positions and 6 closed out — a net gain of 2 holders — while 14 added to existing stakes and 12 trimmed.

The largest buyer was Aberdeen Group, adding an estimated $980K. The largest seller was Woodline Partners, cutting an estimated $3.08M.

  • 64 institutional investors held ProQR Therapeutics (PRQR) as of Q3 2025, up from 62 in Q2 2025.
  • Funds reported $80M of ProQR Therapeutics stock for Q3 2025, down 2.9% quarter-over-quarter.
  • 8 funds opened new ProQR Therapeutics positions in Q3 2025 and 6 closed out, a net change of +2 holders.
  • The largest ProQR Therapeutics buyer in Q3 2025 was Aberdeen Group, an estimated $980K added.
  • The largest ProQR Therapeutics seller in Q3 2025 was Woodline Partners, an estimated $3.08M sold.

Based on aggregated 13F filings for Q3 2025.