Two Sigma Securities’s ProQR Therapeutics PRQR Stock Holding History

Two Sigma Securities’s Portfolio PRQR Stock Details PRQR Fund Activity

Bought

Maintained

Sold

Quarter	Market Value	Status	Shares	Change in Stake	Trade Value	Portfolio Weight	Portfolio Position
2025 Q1	–	Sell	-15,116	Closed	-$40.1K	–	2050
2024 Q4	$40.1K	Buy	+15,116	New	+$48K	0.01%	1213
2024 Q3	–	Sell	-12,471	Closed	-$20.7K	–	3475
2024 Q2	$20.7K	Sell	12,471 -11,262	-47%	-$21.9K	﹤0.01%	2693
2024 Q1	$54.3K	Buy	23,733 +13,096	+123%	+$28K	﹤0.01%	2556
2023 Q4	$21.1K	Buy	+10,637	New	+$16.3K	﹤0.01%	2715
2023 Q2	–	Sell	-19,041	Closed	-$40.6K	–	3226
2023 Q1	$40.6K	Buy	+19,041	New	+$58.2K	﹤0.01%	2295
2022 Q3	–	Sell	-27,821	Closed	-$22K	–	2988
2022 Q2	$22K	Buy	27,821 +13,880	+100%	+$10.3K	﹤0.01%	1944
2022 Q1	$13K	Buy	+13,941	New	+$46.7K	﹤0.01%	2030

Other funds holding PRQR

Adage Capital Partners Boston, Massachusetts $64.8B AUM 42.7% 1-Year Est. Return

PFM

Privium Fund Management Amsterdam, Netherlands $480M AUM 77.45% 1-Year Est. Return

AAA

Affinity Asset Advisors New York $1.94B AUM 374.45% 1-Year Est. Return

Millennium Management New York $240B AUM 35.51% 1-Year Est. Return

SCM

Sio Capital Management New York $697M AUM 79.73% 1-Year Est. Return

Aberdeen Group Edinburgh, United Kingdom $61.9B AUM 29.81% 1-Year Est. Return

UBS Group Zurich, Switzerland $666B AUM 30.12% 1-Year Est. Return

KCM

Kynam Capital Management Princeton, New Jersey $1.62B AUM 138.67% 1-Year Est. Return

DCM

DAFNA Capital Management Los Angeles, California $440M AUM 109.12% 1-Year Est. Return

Siren LLC Greenwich, Connecticut $3.61B AUM 203.3% 1-Year Est. Return

Two Sigma Securities's PRQR Position: Q1 2025 in Review

Two Sigma Securities sold out of ProQR Therapeutics (PRQR) in Q1 2025, closing a stake of 15,116 shares — an estimated $40.1K sold.

Two Sigma Securities first reported a position in PRQR in Q1 2022 and held it in 7 quarters. The position peaked at $54.3K in Q1 2024. 65 funds tracked by Wall St. Rank hold PRQR as of Q1 2025.

Two Sigma Securities reported no remaining ProQR Therapeutics position as of Q1 2025 after selling out during the quarter.
Two Sigma Securities sold 15,116 ProQR Therapeutics shares in Q1 2025, an estimated $40.1K.
Two Sigma Securities first reported a position in ProQR Therapeutics in Q1 2022 and held it in 7 quarters.
Two Sigma Securities's ProQR Therapeutics position peaked at $54.3K in Q1 2024.
65 funds tracked by Wall St. Rank held ProQR Therapeutics as of Q1 2025.

Based on Two Sigma Securities's 13F filing for Q1 2025, filed 15 May 2025.