Two Sigma Securities’s ProQR Therapeutics PRQR Stock Holding History

Two Sigma Securities’s Portfolio PRQR Stock Details PRQR Fund Activity

Bought

Maintained

Sold

Quarter	Market Value	Status	Shares	Change in Stake	Trade Value	Portfolio Weight	Portfolio Position
2026 Q2	$29.8K	Buy	+16,016	New	+$26.4K	﹤0.01%	1443
2025 Q1	–	Sell	-15,116	Closed	-$40.1K	–	2050
2024 Q4	$40.1K	Buy	+15,116	New	+$48K	0.01%	1213
2024 Q3	–	Sell	-12,471	Closed	-$20.7K	–	3475
2024 Q2	$20.7K	Sell	12,471 -11,262	-47%	-$21.9K	﹤0.01%	2693
2024 Q1	$54.3K	Buy	23,733 +13,096	+123%	+$28K	﹤0.01%	2556
2023 Q4	$21.1K	Buy	+10,637	New	+$16.3K	﹤0.01%	2715
2023 Q2	–	Sell	-19,041	Closed	-$40.6K	–	3226
2023 Q1	$40.6K	Buy	+19,041	New	+$58.2K	﹤0.01%	2295
2022 Q3	–	Sell	-27,821	Closed	-$22K	–	2988
2022 Q2	$22K	Buy	27,821 +13,880	+100%	+$10.3K	﹤0.01%	1944
2022 Q1	$13K	Buy	+13,941	New	+$46.7K	﹤0.01%	2030

Other funds holding PRQR

Adage Capital Partners Boston, Massachusetts $71.3B AUM 56.8% 1-Year Est. Return

Aberdeen Group Edinburgh, United Kingdom $71.2B AUM 41.74% 1-Year Est. Return

AAA

Affinity Asset Advisors New York $2.21B AUM 431.26% 1-Year Est. Return

PFM

Privium Fund Management Amsterdam, Netherlands $544M AUM 72.49% 1-Year Est. Return

Ikarian Capital Dallas, Texas $928M AUM 596.14% 1-Year Est. Return

Woodline Partners San Francisco, California $32.4B AUM 58.5% 1-Year Est. Return

HCM

Heights Capital Management San Francisco, California $433M AUM 8.59% 1-Year Est. Return

Morgan Stanley New York $1.89T AUM 35.08% 1-Year Est. Return

SFM

Sphera Funds Management Tel Aviv, Israel $767M AUM 119.71% 1-Year Est. Return

KCM

Kynam Capital Management Princeton, New Jersey $1.81B AUM 192.15% 1-Year Est. Return

Two Sigma Securities's PRQR Position: Q2 2026 in Review

Two Sigma Securities opened a new position in ProQR Therapeutics (PRQR) in Q2 2026: 16,016 shares worth $29.8K. The stake represents ﹤0.01% of the portfolio and ranks #1443 among its holdings. This is a return to the name: Two Sigma Securities previously reported a position in PRQR as recently as Q4 2024.

Two Sigma Securities first reported a position in PRQR in Q1 2022 and has held it in 8 quarters since. The position peaked at $54.3K in Q1 2024. 70 funds tracked by Wall St. Rank hold PRQR as of Q2 2026.

Two Sigma Securities held 16,016 shares of ProQR Therapeutics worth $29.8K as of Q2 2026.
ProQR Therapeutics was a new Two Sigma Securities position in Q2 2026.
ProQR Therapeutics made up ﹤0.01% of Two Sigma Securities's portfolio in Q2 2026, its #1443 holding.
Two Sigma Securities first reported a position in ProQR Therapeutics in Q1 2022 and has held it in 8 quarters since.
Two Sigma Securities's ProQR Therapeutics position peaked at $54.3K in Q1 2024.
70 funds tracked by Wall St. Rank held ProQR Therapeutics as of Q2 2026.

Based on Two Sigma Securities's 13F filing for Q2 2026, filed 14 Aug 2026.