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Prime Medicine

120 hedge funds and large institutions have $145M invested in Prime Medicine in 2025 Q2 according to their latest regulatory filings, with 29 funds opening new positions, 37 increasing their positions, 34 reducing their positions, and 32 closing their positions.

New
Increased
Maintained
Reduced
Closed

more capital invested

Capital invested by funds: $ → $

more call options, than puts

Call options by funds: $ | Put options by funds: $

more repeat investments, than reductions

Existing positions increased: | Existing positions reduced:

more funds holding in top 10

Funds holding in top 10:

9% less first-time investments, than exits

New positions opened: 29 | Existing positions closed: 32

1.31% less ownership

Funds ownership: 46.02%44.71% (-1.3%)

2% less funds holding

Funds holding: 123120 (-3)

Holders
120
Holders Change
Holders Change %
% of All Funds
Holding in Top 10
1
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
Increased
Reduced
Closed
Calls
$1.42M
Puts
$1.22M
Net Calls
Net Calls Change

Top Buyers

1 +$5.78M
2 +$2.96M
3 +$2.02M
4
Citadel Advisors
Citadel Advisors
Florida
+$1.29M
5
FAM
Fred Alger Management
New York
+$946K

Top Sellers

1 -$4.03M
2 -$3.72M
3 -$3.29M
4
NAMA
Nikko Asset Management Americas
New York
-$3.28M
5
BBA
Baker Bros. Advisors
New York
-$2.05M
Name Holding Trade Value Shares
Change
Change in
Stake
SCM
101
Sterling Capital Management
North Carolina
$3.89K
Raymond James Financial
102
Raymond James Financial
Florida
$3.86K
EWA
103
EverSource Wealth Advisors
Alabama
$3.36K
S
104
SignatureFD
Georgia
$2.47K
SS
105
SBI Securities
Japan
$1.8K
MCM
106
MAI Capital Management
Ohio
$1.52K
FG
107
Fairman Group
Pennsylvania
$1.24K
Russell Investments Group
108
Russell Investments Group
United Kingdom
$1.19K
Daiwa Securities Group
109
Daiwa Securities Group
Japan
$1K
RIL
110
Rothschild Investment LLC
Illinois
$852
PNC Financial Services Group
111
PNC Financial Services Group
Pennsylvania
$788
FFO
112
Fortitude Family Office
Arizona
$731
PFBT
113
Parkside Financial Bank & Trust
Missouri
$700
PS
114
Principal Securities
Iowa
$692
Osaic Holdings
115
Osaic Holdings
Arizona
$670
LFG
116
Larson Financial Group
Missouri
$494
TWD
117
True Wealth Design
Ohio
$285
FFA
118
Farther Finance Advisors
California
$64
IA
119
IFP Advisors
Florida
$20
BBA
120
Baker Bros. Advisors
New York
EC
121
EcoR1 Capital
California
SB
122
Samsara BioCapital
California
GCP
123
GSA Capital Partners
United Kingdom
VAS
124
Vestmark Advisory Solutions
Massachusetts
Tudor Investment Corp
125
Tudor Investment Corp
Connecticut