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Prime Medicine
PRME

Overview Fund Activity

123 hedge funds and large institutions have $120M invested in Prime Medicine in 2025 Q1 according to their latest regulatory filings, with 21 funds opening new positions, 41 increasing their positions, 35 reducing their positions, and 27 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
123
Holders Change
-7
Holders Change %
-5.38%
% of All Funds
1.67%
Holding in Top 10
1
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
0.01%
New
21
Increased
41
Reduced
35
Closed
27
Calls
$120K
Puts
$237K
Net Calls
-$117K
Net Calls Change
+$193K

Top Buyers

1
Renaissance Technologies
Renaissance Technologies
New York
+$891K
2
AQR Capital Management
AQR Capital Management
Connecticut
+$453K
3
T. Rowe Price Investment Management
T. Rowe Price Investment Management
Maryland
+$329K
4
GCP
GSA Capital Partners
United Kingdom
+$275K
5
Susquehanna International Group
Susquehanna International Group
Pennsylvania
+$210K

Top Sellers

1
AIM
ARK Investment Management
Florida
-$4.09M
2
WHG
Westwood Holdings Group
Texas
-$2.58M
3
Walleye Capital
Walleye Capital
New York
-$1.18M
4
Bank of America
Bank of America
North Carolina
-$632K
5
BlackRock
BlackRock
New York
-$435K
Name Holding Trade Value Shares
Change 		Shares
Change %
VOYA Investment Management
76
VOYA Investment Management
Georgia
$34.3K -$1.89K -951 -5%
PFSRSONJ
77
Police & Firemen's Retirement System of New Jersey
New Jersey
$34K – – –
CIBC World Market
78
CIBC World Market
Ontario, Canada
$33.9K -$4K -2,008 -11%
CGL
79
Clarius Group LLC
Washington
$32K – – –
VPIM
80
Vanguard Personalized Indexing Management
California
$30.3K +$5.69K +2,859 +23%
Invesco
81
Invesco
Georgia
$29.5K -$468 -235 -2%
CWM
82
CIBC World Markets
New York
$25K +$25K +12,585 New
Wealth Enhancement Advisory Services
83
Wealth Enhancement Advisory Services
Minnesota
$24.3K +$24.3K +12,230 New
American Century Companies
84
American Century Companies
Missouri
$22.7K – – –
State Board of Administration of Florida Retirement System
85
State Board of Administration of Florida Retirement System
Florida
$22.7K – – –
Pathstone Holdings
86
Pathstone Holdings
New Jersey
$22.4K -$121 -61 -0.5%
TRCT
87
Tower Research Capital (TRC)
New York
$19.7K +$16.9K +8,512 +609%
FFA
88
Farther Finance Advisors
California
$19.2K +$19.2K +10,737 +41,296%
New York State Common Retirement Fund
89
New York State Common Retirement Fund
New York
$17K – – –
Simplex Trading
90
Simplex Trading
Illinois
$16K +$13.2K +6,918 +474%
Legal & General Group
91
Legal & General Group
United Kingdom
$11.8K -$724 -364 -6%
Mirae Asset Global Investments
92
Mirae Asset Global Investments
South Korea
$8.73K +$36 +18 +0.4%
California State Teachers Retirement System (CalSTRS)
93
California State Teachers Retirement System (CalSTRS)
California
$8.18K – – –
AIP
94
Ameritas Investment Partners
Nebraska
$7.76K – – –
GFM
95
GF Fund Management
China
$6.68K +$1.31K +658 +24%
S
96
SignatureFD
Georgia
$5.27K +$1.98K +996 +60%
AB
97
Amalgamated Bank
New York
$4K +$1.25K +610 +45%
QCG
98
Quadrant Capital Group
Ohio
$3.67K +$2.01K +1,009 +121%
Royal Bank of Canada
99
Royal Bank of Canada
Ontario, Canada
$3K +$874 +478 +41%
EWA
100
EverSource Wealth Advisors
Alabama
$2.01K +$2K +1,006 +16,767%
2 3
4
5 6