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Prime Medicine
PRME

Overview Fund Activity

123 hedge funds and large institutions have $120M invested in Prime Medicine in 2025 Q1 according to their latest regulatory filings, with 21 funds opening new positions, 41 increasing their positions, 35 reducing their positions, and 27 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
123
Holders Change
-7
Holders Change %
-5.38%
% of All Funds
1.67%
Holding in Top 10
1
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
0.01%
New
21
Increased
41
Reduced
35
Closed
27
Calls
$120K
Puts
$237K
Net Calls
-$117K
Net Calls Change
+$193K

Top Buyers

1
Renaissance Technologies
Renaissance Technologies
New York
+$891K
2
AQR Capital Management
AQR Capital Management
Connecticut
+$453K
3
T. Rowe Price Investment Management
T. Rowe Price Investment Management
Maryland
+$329K
4
GCP
GSA Capital Partners
United Kingdom
+$275K
5
Susquehanna International Group
Susquehanna International Group
Pennsylvania
+$210K

Top Sellers

1
AIM
ARK Investment Management
Florida
-$4.09M
2
WHG
Westwood Holdings Group
Texas
-$2.58M
3
Walleye Capital
Walleye Capital
New York
-$1.18M
4
Bank of America
Bank of America
North Carolina
-$632K
5
BlackRock
BlackRock
New York
-$435K
Name Holding Trade Value Shares
Change 		Shares
Change %
SG Americas Securities
51
SG Americas Securities
New York
$102K -$17.4K -8,773 -15%
Jacobs Levy Equity Management
52
Jacobs Levy Equity Management
New Jersey
$101K +$101K +50,514 New
TD Asset Management
53
TD Asset Management
Ontario, Canada
$92.4K – – –
Citigroup
54
Citigroup
New York
$84.2K -$10.2K -5,129 -11%
BIG
55
Brooklyn Investment Group
New York
$79.5K +$75.8K +38,073 +2,010%
Verition Fund Management
56
Verition Fund Management
Connecticut
$76.1K -$130K -65,290 -63%
JPMorgan Chase & Co
57
JPMorgan Chase & Co
New York
$71K +$46 +23 +0.1%
LCS
58
Levin Capital Strategies
New York
$69.7K -$79.6K -40,000 -53%
IC
59
IEQ Capital
California
$69.4K +$69.4K +34,882 New
Mirae Asset Global ETFs Holdings
60
Mirae Asset Global ETFs Holdings
Hong Kong
$67.5K +$2.82K +1,419 +4%
CAG
61
Crestwood Advisors Group
Massachusetts
$63.1K – – –
Cerity Partners
62
Cerity Partners
New York
$62.5K +$62.5K +31,387 New
BNP Paribas Financial Markets
63
BNP Paribas Financial Markets
France
$62.3K +$22.3K +11,226 +56%
BHCM
64
Brevan Howard Capital Management
Jersey
$56.7K +$56.7K +28,478 New
CF
65
Corebridge Financial
Texas
$55.3K -$820 -412 -1%
CUAMC
66
China Universal Asset Management Company
China
$52.4K -$2.99K -1,502 -5%
QC
67
Quadrature Capital
United Kingdom
$49.6K +$49.6K +24,802 New
Manulife (Manufacturers Life Insurance)
68
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$49.6K +$2.65K +1,332 +6%
PCIA
69
Prime Capital Investment Advisors
Kansas
$48.3K +$609 +306 +1%
Envestnet Asset Management
70
Envestnet Asset Management
Illinois
$46.8K +$3.9K +1,958 +9%
HighTower Advisors
71
HighTower Advisors
Illinois
$43.1K +$111 +56 +0.3%
AF
72
Avanza Fonder
Sweden
$42.8K +$2.57K +1,438 +6%
BEI
73
Benjamin Edwards Inc
Missouri
$42K -$1.63K -820 -4%
Carson Wealth (CWM LLC)
74
Carson Wealth (CWM LLC)
Nebraska
$41K +$36.1K +18,034 +742%
ProShare Advisors
75
ProShare Advisors
Maryland
$36.2K -$7.94K -3,992 -18%
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