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Prime Medicine
PRME

66 hedge funds and large institutions have $768M invested in Prime Medicine in 2022 Q4 according to their latest regulatory filings, with 66 funds opening new positions, increasing their positions, reducing their positions, and closing their positions.

New
Increased
Maintained
Reduced
Closed

42.51% more ownership

Funds ownership: 0% → 42.51% (+43%)

Holders
66
Holders Change
+66
Holders Change %
–
% of All Funds
1.06%
Holding in Top 10
3
Holding in Top 10 Change
+3
Holding in Top 10 Change %
% of All Funds
0.05%
New
66
Increased
–
Reduced
–
Closed
–
Calls
–
Puts
–
Net Calls
–
Net Calls Change
–

Top Buyers

Rank Fund Capital Flow
1
AI
Alphabet Inc
California
+$240M
2
Fidelity Investments
Fidelity Investments
Massachusetts
+$153M
3
T. Rowe Price Associates
T. Rowe Price Associates
Maryland
+$43M
4
RG
Redmile Group
California
+$39.9M
5
MM
MWG Management
British Virgin Islands
+$33.2M

Top Sellers

No sellers this quarter
Name Holding Trade Value Shares
Change 		Change in
Stake
GCM
26
Ghisallo Capital Management
Massachusetts
$1.3M +$1.26M +70,000 New
LCM
27
Laurion Capital Management
New York
$1.11M +$1.08M +60,000 New
Manulife (Manufacturers Life Insurance)
28
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$887K +$813K +44,989 New
Bank of America
29
Bank of America
North Carolina
$880K +$855K +47,359 New
PMEF
30
Point72 Middle East FZE
United Arab Emirates
$699K +$679K +37,609 New
BM
31
Brandywine Managers
Delaware
$613K +$596K +32,977 New
Walleye Capital
32
Walleye Capital
New York
$557K +$542K +30,000 New
Bank of New York Mellon
33
Bank of New York Mellon
New York
$539K +$524K +29,016 New
TD Asset Management
34
TD Asset Management
Ontario, Canada
$444K +$432K +23,922 New
Morgan Stanley
35
Morgan Stanley
New York
$379K +$368K +20,389 New
LP
36
LMR Partners
United Kingdom
$330K +$321K +17,760 New
CGL
37
Clarius Group LLC
Washington
$299K +$290K +16,080 New
N
38
Nuveen
North Carolina
$262K +$255K +14,128 New
OC
39
Oppenheimer & Co
New York
$260K +$253K +14,012 New
LCS
40
Levin Capital Strategies
New York
$197K +$191K +10,585 New
SIM
41
Sandia Investment Management
Massachusetts
$186K +$181K +10,000 New
JP Morgan Chase
42
JP Morgan Chase
New York
$184K +$178K +9,874 New
PCM
43
Penserra Capital Management
California
$140K +$137K +7,570 New
MIM
44
MetLife Investment Management
New Jersey
$113K +$110K +6,091 New
Osaic Holdings
45
Osaic Holdings
Arizona
$112K +$109K +6,029 New
New York State Common Retirement Fund
46
New York State Common Retirement Fund
New York
$92.9K +$90.3K +5,000 New
AIG
47
American International Group
New York
$91.2K +$88.7K +4,909 New
Deutsche Bank
48
Deutsche Bank
Germany
$83.1K +$80.8K +4,473 New
California State Teachers Retirement System (CalSTRS)
49
California State Teachers Retirement System (CalSTRS)
California
$77K +$74.9K +4,144 New
APP
50
Alpha Paradigm Partners
Illinois
$72K +$70.4K +3,895 New
1
2
3

PRME Hedge Fund Activity: Q4 2022 in Review

66 of the 6,221 institutional investors tracked by Wall St. Rank reported a position in Prime Medicine (PRME) for Q4 2022, worth a combined $768M.

Buyers outnumbered sellers: 66 funds opened new PRME positions and 0 closed out — a net gain of 66 holders — while 0 added to existing stakes and 0 trimmed.

The largest buyer was Alphabet Inc, opening a new position worth an estimated $240M.

  • 66 institutional investors held Prime Medicine (PRME) as of Q4 2022, up from 0 in Q3 2022.
  • Funds reported $768M of Prime Medicine stock for Q4 2022.
  • 66 funds opened new Prime Medicine positions in Q4 2022 and 0 closed out, a net change of +66 holders.
  • The largest Prime Medicine buyer in Q4 2022 was Alphabet Inc, an estimated $240M added.

Based on aggregated 13F filings for Q4 2022.