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Opko Health

233 hedge funds and large institutions have $304M invested in Opko Health in 2025 Q3 according to their latest regulatory filings, with 29 funds opening new positions, 77 increasing their positions, 53 reducing their positions, and 15 closing their positions.

New
Increased
Maintained
Reduced
Closed

1,936% more call options, than puts

Call options by funds: $4.26M | Put options by funds: $209K

93% more first-time investments, than exits

New positions opened: 29 | Existing positions closed: 15

45% more repeat investments, than reductions

Existing positions increased: 77 | Existing positions reduced: 53

12% more capital invested

Capital invested by funds: $270M → $304M (+$33.2M)

5% more funds holding

Funds holding: 222233 (+11)

1.14% less ownership

Funds ownership: 25.87%24.73% (-1.1%)

Holders
233
Holders Change
+11
Holders Change %
+4.95%
% of All Funds
3.06%
Holding in Top 10
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
29
Increased
77
Reduced
53
Closed
15
Calls
$4.26M
Puts
$209K
Net Calls
+$4.05M
Net Calls Change
+$847K
Name Holding Trade Value Shares
Change
Change in
Stake
PAG
101
Private Advisor Group
New Jersey
$85.7K
Zurich Cantonal Bank
102
Zurich Cantonal Bank
Switzerland
$85.5K
Prudential Financial
103
Prudential Financial
New Jersey
$84.9K +$10.9K +7,930 +17%
TCA
104
Transcend Capital Advisors
New Jersey
$81.5K +$2.35K +1,714 +3%
First Manhattan
105
First Manhattan
New York
$80.2K
Canada Life
106
Canada Life
Manitoba, Canada
$79K
FNB
107
Farmers National Bank
Kentucky
$78K
HT
108
Headlands Technologies
Illinois
$70.1K -$17.1K -12,484 -22%
CBU
109
CIBC Bancorp USA
Illinois
$68K +$60.2K +43,868 New
Squarepoint
110
Squarepoint
New York
$65.9K -$68.6K -49,915 -54%
AI
111
Atom Investors
Texas
$64.9K -$1.94K -1,410 -3%
Victory Capital Management
112
Victory Capital Management
Texas
$64K -$628 -457 -1%
RAM
113
RK Asset Management
Michigan
$63K
WIA
114
World Investment Advisors
California
$63K
HighTower Advisors
115
HighTower Advisors
Illinois
$62.6K +$2.06K +1,501 +4%
State of Wisconsin Investment Board
116
State of Wisconsin Investment Board
Wisconsin
$60.6K +$24.6K +17,904 +84%
EC
117
EntryPoint Capital
New York
$60.2K +$53.3K +38,828 New
KAS
118
Kestra Advisory Services
Texas
$60.2K
Russell Investments Group
119
Russell Investments Group
United Kingdom
$53.8K +$46.8K +34,070 +5,495%
Cerity Partners
120
Cerity Partners
New York
$53.6K +$47.5K +34,566 New
CL
121
Choreo LLC
Illinois
$52.3K
Citigroup
122
Citigroup
New York
$50.8K -$185K -134,363 -80%
X
123
Xponance
Pennsylvania
$49.9K +$5.8K +4,221 +15%
NPF
124
Norris Perne & French
Michigan
$49.6K
OA
125
Operose Advisors
Wisconsin
$49.6K

OPK Hedge Fund Activity: Q3 2025 in Review

233 of the 7,619 institutional investors tracked by Wall St. Rank reported a position in Opko Health (OPK) for Q3 2025, worth a combined $304M — up 12% from $270M a quarter earlier.

Buyers outnumbered sellers: 29 funds opened new OPK positions and 15 closed out — a net gain of 14 holders — while 77 added to existing stakes and 53 trimmed.

The largest buyer was Whitefort Capital Management, adding an estimated $4.29M. The largest seller was Weiss Asset Management, cutting an estimated $4.98M.

  • 233 institutional investors held Opko Health (OPK) as of Q3 2025, up from 222 in Q2 2025.
  • Funds reported $304M of Opko Health stock for Q3 2025, up 12% quarter-over-quarter.
  • 29 funds opened new Opko Health positions in Q3 2025 and 15 closed out, a net change of +14 holders.
  • The largest Opko Health buyer in Q3 2025 was Whitefort Capital Management, an estimated $4.29M added.
  • The largest Opko Health seller in Q3 2025 was Weiss Asset Management, an estimated $4.98M sold.

Based on aggregated 13F filings for Q3 2025.