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Opko Health

255 hedge funds and large institutions have $401M invested in Opko Health in 2025 Q1 according to their latest regulatory filings, with 43 funds opening new positions, 76 increasing their positions, 58 reducing their positions, and 23 closing their positions.

New
Increased
Maintained
Reduced
Closed

490% more call options, than puts

Call options by funds: $5.13M | Put options by funds: $870K

87% more first-time investments, than exits

New positions opened: 43 | Existing positions closed: 23

38% more capital invested

Capital invested by funds: $290M → $401M (+$111M)

31% more repeat investments, than reductions

Existing positions increased: 76 | Existing positions reduced: 58

9% more funds holding

Funds holding: 235255 (+20)

7.1% more ownership

Funds ownership: 28.95%36.05% (+7.1%)

Holders
255
Holders Change
+20
Holders Change %
+8.51%
% of All Funds
3.42%
Holding in Top 10
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
43
Increased
76
Reduced
58
Closed
23
Calls
$5.13M
Puts
$870K
Net Calls
+$4.26M
Net Calls Change
+$12.2M
Name Holding Trade Value Shares
Change
Change in
Stake
TSS
101
Two Sigma Securities
New York
$126K -$222 -135 -0.2%
Wealth Enhancement Advisory Services
102
Wealth Enhancement Advisory Services
Minnesota
$124K +$75.4K +45,798 +158%
Carson Wealth (CWM LLC)
103
Carson Wealth (CWM LLC)
Nebraska
$124K +$111K +67,487 +962%
KK
104
KLP Kapitalforvaltning
Norway
$123K
CWM
105
CIBC World Markets
New York
$117K +$66.4K +40,287 +132%
ProShare Advisors
106
ProShare Advisors
Maryland
$115K -$37.4K -22,685 -25%
CFP
107
Cascade Financial Partners
California
$110K
Pictet Asset Management
108
Pictet Asset Management
Switzerland
$109K
Public Employees Retirement Association of Colorado
109
Public Employees Retirement Association of Colorado
Colorado
$102K
New York State Common Retirement Fund
110
New York State Common Retirement Fund
New York
$101K
Cetera Investment Advisers
111
Cetera Investment Advisers
Illinois
$101K
KPWS
112
Kestra Private Wealth Services
Texas
$97K -$2.06K -1,250 -2%
PNC Financial Services Group
113
PNC Financial Services Group
Pennsylvania
$94.3K
PAG
114
Private Advisor Group
New Jersey
$91.8K +$32.9K +20,000 +57%
Zurich Cantonal Bank
115
Zurich Cantonal Bank
Switzerland
$91.5K
Mercer Global Advisors
116
Mercer Global Advisors
Colorado
$91.2K +$19.4K +11,790 +27%
Canada Life
117
Canada Life
Manitoba, Canada
$90K
HT
118
Headlands Technologies
Illinois
$86.6K +$85.9K +52,149 New
First Manhattan
119
First Manhattan
New York
$85.9K
TCA
120
Transcend Capital Advisors
New Jersey
$84.4K
Group One Trading
121
Group One Trading
Illinois
$84.3K -$982K -596,291 -92%
KAS
122
Kestra Advisory Services
Texas
$83.5K
FNB
123
Farmers National Bank
Kentucky
$83.5K
JF
124
Jump Financial
Illinois
$81.5K +$80.8K +49,070 New
CAPTRUST Financial Advisors
125
CAPTRUST Financial Advisors
North Carolina
$80.5K +$18K +10,952 +29%

OPK Hedge Fund Activity: Q1 2025 in Review

255 of the 7,458 institutional investors tracked by Wall St. Rank reported a position in Opko Health (OPK) for Q1 2025, worth a combined $401M — up 38% from $290M a quarter earlier.

Buyers outnumbered sellers: 43 funds opened new OPK positions and 23 closed out — a net gain of 20 holders — while 76 added to existing stakes and 58 trimmed.

The largest buyer was Sculptor Capital, opening a new position worth an estimated $20.9M. The largest seller was UBS Group, cutting an estimated $3.96M.

  • 255 institutional investors held Opko Health (OPK) as of Q1 2025, up from 235 in Q4 2024.
  • Funds reported $401M of Opko Health stock for Q1 2025, up 38% quarter-over-quarter.
  • 43 funds opened new Opko Health positions in Q1 2025 and 23 closed out, a net change of +20 holders.
  • The largest Opko Health buyer in Q1 2025 was Sculptor Capital, an estimated $20.9M added.
  • The largest Opko Health seller in Q1 2025 was UBS Group, an estimated $3.96M sold.

Based on aggregated 13F filings for Q1 2025.