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Opko Health

233 hedge funds and large institutions have $304M invested in Opko Health in 2025 Q3 according to their latest regulatory filings, with 29 funds opening new positions, 77 increasing their positions, 53 reducing their positions, and 15 closing their positions.

New
Increased
Maintained
Reduced
Closed

1,936% more call options, than puts

Call options by funds: $4.26M | Put options by funds: $209K

93% more first-time investments, than exits

New positions opened: 29 | Existing positions closed: 15

45% more repeat investments, than reductions

Existing positions increased: 77 | Existing positions reduced: 53

12% more capital invested

Capital invested by funds: $270M → $304M (+$33.2M)

5% more funds holding

Funds holding: 222233 (+11)

1.14% less ownership

Funds ownership: 25.87%24.73% (-1.1%)

Holders
233
Holders Change
+11
Holders Change %
+4.95%
% of All Funds
3.06%
Holding in Top 10
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
29
Increased
77
Reduced
53
Closed
15
Calls
$4.26M
Puts
$209K
Net Calls
+$4.05M
Net Calls Change
+$847K
Name Holding Trade Value Shares
Change
Change in
Stake
Morgan Stanley
26
Morgan Stanley
New York
$1.3M -$1.68M -1,221,453 -59%
UBS AM
27
UBS AM
Illinois
$1.04M -$623K -453,911 -40%
Assenagon Asset Management
28
Assenagon Asset Management
Luxembourg
$1.03M -$336K -244,900 -26%
Commonwealth Equity Services
29
Commonwealth Equity Services
Massachusetts
$918K +$52.1K +37,932 +7%
Barclays
30
Barclays
United Kingdom
$911K -$105K -76,654 -12%
RhumbLine Advisers
31
RhumbLine Advisers
Massachusetts
$861K +$35.5K +25,829 +5%
JP Morgan Chase
32
JP Morgan Chase
New York
$817K -$141K -102,944 -16%
AllianceBernstein
33
AllianceBernstein
Tennessee
$737K +$9.48K +6,900 +1%
California State Teachers Retirement System (CalSTRS)
34
California State Teachers Retirement System (CalSTRS)
California
$644K +$125K +91,269 +28%
Connor, Clark & Lunn Investment Management (CC&L)
35
Connor, Clark & Lunn Investment Management (CC&L)
British Columbia, Canada
$609K +$1.51K +1,097 +0.3%
Legal & General Group
36
Legal & General Group
United Kingdom
$598K +$42.8K +31,155 +9%
Two Sigma Advisers
37
Two Sigma Advisers
New York
$533K -$418K -304,200 -47%
T. Rowe Price Associates
38
T. Rowe Price Associates
Maryland
$533K -$129K -94,220 -22%
Wells Fargo
39
Wells Fargo
California
$531K +$98K +71,392 +26%
Susquehanna International Group
40
Susquehanna International Group
Pennsylvania
$462K -$476K -346,835 -54%
Citadel Advisors
41
Citadel Advisors
Florida
$434K +$85.8K +62,480 +29%
IC
42
IEQ Capital
California
$430K +$231K +168,375 +154%
Deutsche Bank
43
Deutsche Bank
Germany
$427K +$49.7K +36,170 +15%
Royal Bank of Canada
44
Royal Bank of Canada
Ontario, Canada
$423K +$7.44K +5,418 +2%
Jane Street
45
Jane Street
New York
$407K -$1.54M -1,121,714 -81%
Tudor Investment Corp
46
Tudor Investment Corp
Connecticut
$379K
Manulife (Manufacturers Life Insurance)
47
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$367K +$135K +98,079 +71%
ZA
48
Zazove Associates
Nevada
$322K
MIM
49
MetLife Investment Management
New Jersey
$321K -$15.2K -11,097 -5%
Janus Henderson Group
50
Janus Henderson Group
United Kingdom
$319K

OPK Hedge Fund Activity: Q3 2025 in Review

233 of the 7,619 institutional investors tracked by Wall St. Rank reported a position in Opko Health (OPK) for Q3 2025, worth a combined $304M — up 12% from $270M a quarter earlier.

Buyers outnumbered sellers: 29 funds opened new OPK positions and 15 closed out — a net gain of 14 holders — while 77 added to existing stakes and 53 trimmed.

The largest buyer was Whitefort Capital Management, adding an estimated $4.29M. The largest seller was Weiss Asset Management, cutting an estimated $4.98M.

  • 233 institutional investors held Opko Health (OPK) as of Q3 2025, up from 222 in Q2 2025.
  • Funds reported $304M of Opko Health stock for Q3 2025, up 12% quarter-over-quarter.
  • 29 funds opened new Opko Health positions in Q3 2025 and 15 closed out, a net change of +14 holders.
  • The largest Opko Health buyer in Q3 2025 was Whitefort Capital Management, an estimated $4.29M added.
  • The largest Opko Health seller in Q3 2025 was Weiss Asset Management, an estimated $4.98M sold.

Based on aggregated 13F filings for Q3 2025.