Two Sigma Advisers’s Opko Health OPK Stock Holding History

Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake
Trade Value Portfolio Weight Portfolio Position
2026
Q1
Sell
-191,201
Closed -$241K 1505
2025
Q4
$241K Sell
191,201
-152,896
-44% -$213K ﹤0.01% 2050
2025
Q3
$533K Sell
344,097
-304,200
-47% -$418K ﹤0.01% 1736
2025
Q2
$856K Buy
648,297
+96,600
+18% +$132K ﹤0.01% 1515
2025
Q1
$916K Buy
551,697
+170,500
+45% +$281K ﹤0.01% 1510
2024
Q4
$560K Buy
381,197
+8,396
+2% +$12.8K ﹤0.01% 1738
2024
Q3
$555K Sell
372,801
-89,600
-19% -$133K ﹤0.01% 1657
2024
Q2
$578K Sell
462,401
-730,396
-61% -$947K ﹤0.01% 1818
2024
Q1
$1.43M Buy
1,192,797
+55,900
+5% +$55.9K ﹤0.01% 1395
2023
Q4
$1.72M Sell
1,136,897
-176,200
-13% -$255K ﹤0.01% 1377
2023
Q3
$2.1M Sell
1,313,097
-126,100
-9% -$230K 0.01% 1176
2023
Q2
$3.12M Sell
1,439,197
-358,100
-20% -$560K 0.01% 971
2023
Q1
$2.62M Sell
1,797,297
-465,700
-21% -$599K 0.01% 1134
2022
Q4
$2.83M Buy
2,262,997
+140,600
+7% +$222K 0.01% 1047
2022
Q3
$4.01M Buy
2,122,397
+1,275,600
+151% +$3.02M 0.01% 847
2022
Q2
$2.14M Buy
846,797
+504,597
+147% +$1.47M 0.01% 1181
2022
Q1
$1.18M Buy
342,200
+60,900
+22% +$215K ﹤0.01% 1550
2021
Q4
$1.35M Buy
281,300
+261,000
+1,286% +$1.06M ﹤0.01% 1389
2021
Q3
$74K Sell
20,300
-92,600
-82% -$345K ﹤0.01% 2347
2021
Q2
$457K Sell
112,900
-76,000
-40% -$298K ﹤0.01% 1974
2021
Q1
$810K Buy
+188,900
New +$902K ﹤0.01% 1768
2020
Q3
Sell
-908,632
Closed -$3.1M 2573
2020
Q2
$3.1M Sell
908,632
-319,700
-26% -$716K 0.01% 994
2020
Q1
$1.65M Buy
1,228,332
+793,227
+182% +$1.24M 0.01% 1216
2019
Q4
$640K Buy
+435,105
New +$728K ﹤0.01% 1764
2019
Q3
Sell
-14,025
Closed -$34K 2350
2019
Q2
$34K Buy
+14,025
New +$30.6K ﹤0.01% 2272
2019
Q1
Sell
-16,400
Closed -$49K 2418
2018
Q4
$49K Buy
+16,400
New +$55.6K ﹤0.01% 2278
2015
Q3
Sell
-81,211
Closed -$1.31M 1928
2015
Q2
$1.31M Buy
+81,211
New +$1.26M 0.01% 994
2014
Q4
Sell
-28,600
Closed -$243K 2680
2014
Q3
$243K Buy
+28,600
New +$251K ﹤0.01% 2025

Other funds holding OPK

Two Sigma Advisers's OPK Position: Q1 2026 in Review

Two Sigma Advisers sold out of Opko Health (OPK) in Q1 2026, closing a stake of 191,201 shares — an estimated $241K sold.

Two Sigma Advisers first reported a position in OPK in Q3 2014 and held it in 27 quarters. The position peaked at $4.01M in Q3 2022. 236 funds tracked by Wall St. Rank hold OPK as of Q1 2026.

  • Two Sigma Advisers reported no remaining Opko Health position as of Q1 2026 after selling out during the quarter.
  • Two Sigma Advisers sold 191,201 Opko Health shares in Q1 2026, an estimated $241K.
  • Two Sigma Advisers first reported a position in Opko Health in Q3 2014 and held it in 27 quarters.
  • Two Sigma Advisers's Opko Health position peaked at $4.01M in Q3 2022.
  • 236 funds tracked by Wall St. Rank held Opko Health as of Q1 2026.

Based on Two Sigma Advisers's 13F filing for Q1 2026.