Opko Health
OPK
255 hedge funds and large institutions have $401M invested in Opko Health in 2025 Q1 according to their latest regulatory filings, with 43 funds opening new positions, 76 increasing their positions, 58 reducing their positions, and 23 closing their positions.
490% more call options, than puts
Call options by funds: $5.13M | Put options by funds: $870K
87% more first-time investments, than exits
New positions opened: 43 | Existing positions closed: 23
38% more capital invested
Capital invested by funds: $290M → $401M (+$111M)
31% more repeat investments, than reductions
Existing positions increased: 76 | Existing positions reduced: 58
9% more funds holding
Funds holding: 235 → 255 (+20)
7.1% more ownership
Funds ownership: 28.95% → 36.05% (+7.1%)
Top Buyers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
SC
Sculptor Capital
New York
|
+$20.9M |
| 2 |
WAM
Weiss Asset Management
Boston,
Massachusetts
|
+$18.4M |
| 3 |
DM
Deerfield Management
New York
|
+$11.4M |
| 4 |
D.E. Shaw & Co
New York
|
+$7.79M |
| 5 |
Marshall Wace
London,
United Kingdom
|
+$6.55M |
Top Sellers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
UBS Group
Zurich,
Switzerland
|
-$3.96M |
| 2 |
Jane Street
New York
|
-$3.72M |
| 3 |
Citadel Advisors
Miami,
Florida
|
-$2.23M |
| 4 |
IECM
Intrinsic Edge Capital Management
Chicago,
Illinois
|
-$1.62M |
| 5 |
State Street
Boston,
Massachusetts
|
-$1.54M |
| Name | Holding | Trade Value |
Shares Change |
Change in Stake |
|
|---|---|---|---|---|---|
|
CPG
276
Cornerstone Planning Group
Fairfield,
New Jersey
| – | -$1 | -1 | Closed |
|
277
Bessemer Group
Woodbridge,
New Jersey
| – | +$450 | +273 | New |
|
OPK Hedge Fund Activity: Q1 2025 in Review
255 of the 7,458 institutional investors tracked by Wall St. Rank reported a position in Opko Health (OPK) for Q1 2025, worth a combined $401M — up 38% from $290M a quarter earlier.
Buyers outnumbered sellers: 43 funds opened new OPK positions and 23 closed out — a net gain of 20 holders — while 76 added to existing stakes and 58 trimmed.
The largest buyer was Sculptor Capital, opening a new position worth an estimated $20.9M. The largest seller was UBS Group, cutting an estimated $3.96M.
- 255 institutional investors held Opko Health (OPK) as of Q1 2025, up from 235 in Q4 2024.
- Funds reported $401M of Opko Health stock for Q1 2025, up 38% quarter-over-quarter.
- 43 funds opened new Opko Health positions in Q1 2025 and 23 closed out, a net change of +20 holders.
- The largest Opko Health buyer in Q1 2025 was Sculptor Capital, an estimated $20.9M added.
- The largest Opko Health seller in Q1 2025 was UBS Group, an estimated $3.96M sold.
Based on aggregated 13F filings for Q1 2025.