|
1
|
Fidelity Investments
Boston,
Massachusetts
|
$67M
|
+$1.27M
|
+416,932
|
+1%
|
|
|
2
|
Decheng Capital
Menlo Park,
California
|
$59.4M
|
+$58M
|
+19,004,200
|
+273%
|
|
|
3
|
EcoR1 Capital
San Francisco,
California
|
$44M
|
–
|
–
|
–
|
|
|
4
|
|
$38.9M
|
+$2.25M
|
+737,233
|
+5%
|
|
|
5
|
Omega Fund Management
Boston,
Massachusetts
|
$29.9M
|
-$621K
|
-203,544
|
-2%
|
|
|
6
|
Octagon Capital Advisors
New York
|
$27.9M
|
+$35.8M
|
+11,739,913
|
+2,720%
|
|
|
7
|
Vanguard Group
Malvern,
Pennsylvania
|
$24.8M
|
+$2.06M
|
+675,849
|
+7%
|
|
|
8
|
State Street
Boston,
Massachusetts
|
$9.54M
|
+$583K
|
+191,031
|
+5%
|
|
|
9
|
Geode Capital Management
Boston,
Massachusetts
|
$9.23M
|
+$599K
|
+196,247
|
+5%
|
|
|
10
|
Tang Capital Management
San Diego,
California
|
$8.93M
|
+$452K
|
+148,136
|
+4%
|
|
|
11
|
Abrams Capital Management
Boston,
Massachusetts
|
$8.73M
|
–
|
–
|
–
|
|
|
12
|
Redmile Group
San Francisco,
California
|
$6.94M
|
–
|
–
|
–
|
|
|
13
|
Citadel Advisors
Miami,
Florida
|
$6.32M
|
+$2.32M
|
+762,142
|
+38%
|
|
|
14
|
Aisling Capital Management
New York
|
$5.82M
|
–
|
–
|
–
|
|
|
15
|
Dimensional Fund Advisors
Austin,
Texas
|
$3.8M
|
+$1.96M
|
+641,543
|
+63%
|
|
|
16
|
Laurion Capital Management
New York
|
$3.64M
|
–
|
–
|
–
|
|
|
17
|
Nuveen
Charlotte,
North Carolina
|
$3.62M
|
+$226K
|
+74,225
|
+5%
|
|
|
18
|
Northern Trust
Chicago,
Illinois
|
$3.49M
|
+$780K
|
+255,809
|
+20%
|
|
|
19
|
Charles Schwab
San Francisco,
California
|
$3.19M
|
+$185K
|
+60,590
|
+5%
|
|
|
20
|
Millennium Management
New York
|
$3.1M
|
+$2.84M
|
+932,686
|
+221%
|
|
|
21
|
Ghost Tree Capital
New York
|
$3.09M
|
+$610K
|
+200,000
|
+17%
|
|
|
22
|
|
$3.03M
|
+$563K
|
+184,664
|
+16%
|
|
|
23
|
|
$2.91M
|
–
|
–
|
–
|
|
|
24
|
Barclays
London,
United Kingdom
|
$2.79M
|
-$1.02M
|
-333,817
|
-22%
|
|
|
25
|
Frazier Life Sciences Management
Palo Alto,
California
|
$2.79M
|
+$3.72M
|
+1,218,236
|
New
|
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