|
1
|
Fidelity Investments
Boston,
Massachusetts
|
$269M
|
-$4.27M
|
-464,134
|
-1%
|
|
|
2
|
Omega Fund Management
Boston,
Massachusetts
|
$195M
|
-$48.3M
|
-5,255,036
|
-19%
|
|
|
3
|
EcoR1 Capital
San Francisco,
California
|
$118M
|
+$1.7M
|
+185,026
|
+1%
|
|
|
4
|
Vanguard Group
Malvern,
Pennsylvania
|
$95.7M
|
-$5.9M
|
-641,975
|
-5%
|
|
|
5
|
|
$91.8M
|
+$49.6M
|
+5,397,329
|
+100%
|
|
|
6
|
Baupost Group
Boston,
Massachusetts
|
$73M
|
–
|
–
|
–
|
|
|
7
|
Avidity Partners Management
Dallas,
Texas
|
$62.8M
|
+$1.09M
|
+119,000
|
+2%
|
|
|
8
|
Citadel Advisors
Miami,
Florida
|
$46.8M
|
-$1.3M
|
-141,018
|
-2%
|
|
|
9
|
Boxer Capital
San Diego,
California
|
$36.9M
|
–
|
–
|
–
|
|
|
10
|
Abrams Capital Management
Boston,
Massachusetts
|
$32.4M
|
–
|
–
|
–
|
|
|
11
|
Redmile Group
San Francisco,
California
|
$31.2M
|
-$8M
|
-870,000
|
-19%
|
|
|
12
|
Deerfield Management
New York
|
$30.4M
|
–
|
–
|
–
|
|
|
13
|
Perceptive Advisors
New York
|
$24.8M
|
-$1.1M
|
-120,181
|
-4%
|
|
|
14
|
State Street
Boston,
Massachusetts
|
$23.2M
|
+$12.2M
|
+1,330,900
|
+95%
|
|
|
15
|
Aisling Capital Management
New York
|
$21.6M
|
–
|
–
|
–
|
|
|
16
|
Geode Capital Management
Boston,
Massachusetts
|
$18.3M
|
+$6.88M
|
+748,225
|
+53%
|
|
|
17
|
Farallon Capital Management
San Francisco,
California
|
$12.2M
|
-$7.17M
|
-780,000
|
-35%
|
|
|
18
|
Northern Trust
Chicago,
Illinois
|
$12M
|
+$6.15M
|
+669,667
|
+90%
|
|
|
19
|
|
$10.8M
|
+$11.7M
|
+1,270,504
|
New
|
|
|
20
|
Ally Bridge Group
New York
|
$10.2M
|
-$4.26M
|
-463,795
|
-28%
|
|
|
21
|
Ensign Peak Advisors
Salt Lake City,
Utah
|
$9.84M
|
-$598K
|
-65,110
|
-5%
|
|
|
22
|
Charles Schwab
San Francisco,
California
|
$7.72M
|
+$1.95M
|
+212,255
|
+31%
|
|
|
23
|
Nuveen
Charlotte,
North Carolina
|
$6.23M
|
+$2.83M
|
+307,748
|
+72%
|
|
|
24
|
Ameriprise
Minneapolis,
Minnesota
|
$6.19M
|
+$1.1K
|
+120
|
+0%
|
|
|
25
|
AWM Investment Company
New York
|
$5.95M
|
+$2.76M
|
+300,000
|
+75%
|
|
