|
1
|
Fidelity Investments
Boston,
Massachusetts
|
$319M
|
-$4.69M
|
-517,297
|
-2%
|
|
|
2
|
Omega Fund Management
Boston,
Massachusetts
|
$280M
|
–
|
–
|
–
|
|
|
3
|
EcoR1 Capital
San Francisco,
California
|
$136M
|
–
|
–
|
–
|
|
|
4
|
Vanguard Group
Malvern,
Pennsylvania
|
$118M
|
+$7.31M
|
+806,166
|
+7%
|
|
|
5
|
Baupost Group
Boston,
Massachusetts
|
$85.4M
|
–
|
–
|
–
|
|
|
6
|
Avidity Partners Management
Dallas,
Texas
|
$72.2M
|
+$2.69M
|
+297,112
|
+4%
|
|
|
7
|
Citadel Advisors
Miami,
Florida
|
$56.1M
|
-$6.86M
|
-756,400
|
-12%
|
|
|
8
|
|
$53.7M
|
+$19.8M
|
+2,186,242
|
+68%
|
|
|
9
|
Redmile Group
San Francisco,
California
|
$45.1M
|
–
|
–
|
–
|
|
|
10
|
Boxer Capital
San Diego,
California
|
$43.1M
|
–
|
–
|
–
|
|
|
11
|
Abrams Capital Management
Boston,
Massachusetts
|
$37.9M
|
–
|
–
|
–
|
|
|
12
|
Deerfield Management
New York
|
$35.6M
|
–
|
–
|
–
|
|
|
13
|
Perceptive Advisors
New York
|
$30.2M
|
–
|
–
|
–
|
|
|
14
|
Aisling Capital Management
New York
|
$25.3M
|
–
|
–
|
–
|
|
|
15
|
Farallon Capital Management
San Francisco,
California
|
$22M
|
-$2.62M
|
-288,600
|
-12%
|
|
|
16
|
Ally Bridge Group
New York
|
$16.5M
|
-$427K
|
-47,144
|
-3%
|
|
|
17
|
Geode Capital Management
Boston,
Massachusetts
|
$14M
|
+$5.49M
|
+605,416
|
+75%
|
|
|
18
|
State Street
Boston,
Massachusetts
|
$13.9M
|
+$4.37M
|
+482,631
|
+52%
|
|
|
19
|
Ensign Peak Advisors
Salt Lake City,
Utah
|
$12.2M
|
+$321K
|
+35,428
|
+3%
|
|
|
20
|
Northern Trust
Chicago,
Illinois
|
$7.41M
|
+$2.41M
|
+265,917
|
+55%
|
|
|
21
|
Ameriprise
Minneapolis,
Minnesota
|
$7.24M
|
–
|
–
|
–
|
|
|
22
|
Charles Schwab
San Francisco,
California
|
$6.91M
|
+$2.88M
|
+317,882
|
+84%
|
|
|
23
|
Hudson Bay Capital Management
Stamford,
Connecticut
|
$4.97M
|
-$6.38K
|
-704
|
-0.1%
|
|
|
24
|
Nuveen
Charlotte,
North Carolina
|
$4.23M
|
+$1.58M
|
+174,318
|
+69%
|
|
|
25
|
AWM Investment Company
New York
|
$3.98M
|
-$417K
|
-46,024
|
-10%
|
|
