|
1
|
Fidelity Investments
Boston,
Massachusetts
|
$296M
|
+$4.14M
|
+362,976
|
+1%
|
|
|
2
|
Omega Fund Management
Boston,
Massachusetts
|
$263M
|
–
|
–
|
–
|
|
|
3
|
EcoR1 Capital
San Francisco,
California
|
$128M
|
+$5.3M
|
+464,500
|
+4%
|
|
|
4
|
Vanguard Group
Malvern,
Pennsylvania
|
$103M
|
+$47.2M
|
+4,139,205
|
+59%
|
|
|
5
|
Baupost Group
Boston,
Massachusetts
|
$77.1M
|
–
|
–
|
–
|
|
|
6
|
Avidity Partners Management
Dallas,
Texas
|
$64.9M
|
-$6.34M
|
-555,565
|
-7%
|
|
|
7
|
Citadel Advisors
Miami,
Florida
|
$57.9M
|
-$2.11M
|
-184,985
|
-3%
|
|
|
8
|
Redmile Group
San Francisco,
California
|
$42.3M
|
–
|
–
|
–
|
|
|
9
|
Boxer Capital
San Diego,
California
|
$40.4M
|
–
|
–
|
–
|
|
|
10
|
Abrams Capital Management
Boston,
Massachusetts
|
$35.5M
|
–
|
–
|
–
|
|
|
11
|
Deerfield Management
New York
|
$33.3M
|
+$6.58M
|
+577,233
|
+19%
|
|
|
12
|
|
$29.9M
|
+$20.2M
|
+1,773,029
|
+123%
|
|
|
13
|
Perceptive Advisors
New York
|
$28.3M
|
–
|
–
|
–
|
|
|
14
|
Aisling Capital Management
New York
|
$23.7M
|
–
|
–
|
–
|
|
|
15
|
Farallon Capital Management
San Francisco,
California
|
$23.3M
|
-$16K
|
-1,400
|
-0.1%
|
|
|
16
|
Ally Bridge Group
New York
|
$15.9M
|
-$3.33M
|
-291,909
|
-15%
|
|
|
17
|
Ensign Peak Advisors
Salt Lake City,
Utah
|
$11.1M
|
+$3.86M
|
+338,888
|
+40%
|
|
|
18
|
State Street
Boston,
Massachusetts
|
$8.57M
|
+$10M
|
+878,005
|
+2,066%
|
|
|
19
|
Geode Capital Management
Boston,
Massachusetts
|
$7.48M
|
+$3.22M
|
+282,357
|
+54%
|
|
|
20
|
Franklin Resources
San Mateo,
California
|
$7.45M
|
–
|
–
|
–
|
|
|
21
|
Ameriprise
Minneapolis,
Minnesota
|
$6.78M
|
–
|
–
|
–
|
|
|
22
|
Hudson Bay Capital Management
Stamford,
Connecticut
|
$4.66M
|
-$7.75M
|
-679,630
|
-58%
|
|
|
23
|
Northern Trust
Chicago,
Illinois
|
$4.47M
|
+$4.12M
|
+361,300
|
+305%
|
|
|
24
|
Renaissance Technologies
New York
|
$4.35M
|
+$5.32M
|
+466,800
|
New
|
|
|
25
|
AWM Investment Company
New York
|
$4.15M
|
+$116K
|
+10,200
|
+2%
|
|
