MREO

Mereo BioPharma
MREO

Overview Fund Activity

82 hedge funds and large institutions have $267M invested in Mereo BioPharma in 2025 Q2 according to their latest regulatory filings, with 11 funds opening new positions, 30 increasing their positions, 19 reducing their positions, and 17 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
82
Holders Change
-7
Holders Change %
-7.87%
% of All Funds
1.1%
Holding in Top 10
1
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
0.01%
New
11
Increased
30
Reduced
19
Closed
17
Calls
$8.29M
Puts
$3.35M
Net Calls
+$4.95M
Net Calls Change
+$3.2M

Top Buyers

1
FLSM
Frazier Life Sciences Management
California
+$4.39M
2
Goldman Sachs
Goldman Sachs
New York
+$2.61M
3
Aberdeen Group
Aberdeen Group
United Kingdom
+$2.28M
4
Fidelity Investments
Fidelity Investments
Massachusetts
+$1.95M
5
Citadel Advisors
Citadel Advisors
Florida
+$1.13M

Top Sellers

1
Janus Henderson Group
Janus Henderson Group
United Kingdom
-$13.7M
2
RSCM
Rock Springs Capital Management
Maryland
-$6.01M
3
Adage Capital Partners
Adage Capital Partners
Massachusetts
-$3.83M
4
Morgan Stanley
Morgan Stanley
New York
-$3.78M
5
UBS AM
UBS AM
Illinois
-$3.53M
Name Holding Trade Value Shares
Change 		Shares
Change %
Bank of America
26
Bank of America
North Carolina
$1.19M -$24 -9 -0%
MAM
27
Monaco Asset Management
Monaco
$1.07M -$58.2K -21,468 -5%
UBS Group
28
UBS Group
Switzerland
$1.01M -$1.51M -558,516 -60%
Susquehanna International Group
29
Susquehanna International Group
Pennsylvania
$980K +$507K +187,164 +107%
CF
30
Cantor Fitzgerald
New York
$929K -$32.6K -12,043 -3%
DMKJ
31
David M. Knott Jr
$865K – – –
PP
32
Paloma Partners
Connecticut
$804K +$804K +296,659 New
KCM
33
Knoll Capital Management
Florida
$706K – – –
Jane Street
34
Jane Street
New York
$671K +$278K +102,638 +71%
Simplex Trading
35
Simplex Trading
Illinois
$545K +$534K +197,024 +4,786%
CM
36
Caption Management
Oklahoma
$535K +$252K +92,816 +89%
Two Sigma Advisers
37
Two Sigma Advisers
New York
$392K +$312K +115,300 +394%
Group One Trading
38
Group One Trading
Illinois
$378K +$285K +105,278 +307%
DIG
39
Dauntless Investment Group
New Hampshire
$363K +$363K +134,122 New
Nomura Holdings
40
Nomura Holdings
Japan
$339K +$339K +125,000 New
NIM
41
NEOS Investment Management
Connecticut
$278K -$1.5M -552,083 -84%
TE
42
Tema ETFs
New York
$278K -$1.5M -552,083 -84%
Geode Capital Management
43
Geode Capital Management
Massachusetts
$251K +$1.02K +378 +0.4%
XT
44
XTX Topco
Cayman Islands
$188K +$188K +69,341 New
Point72 Asset Management
45
Point72 Asset Management
Connecticut
$160K +$63.4K +23,384 +65%
JGC
46
J. Goldman & Co
New York
$142K -$73.2K -27,003 -34%
State Street
47
State Street
Massachusetts
$122K -$1.94K -717 -2%
CHAM
48
Clear Harbor Asset Management
Connecticut
$114K – – –
AF
49
Avanza Fonder
Sweden
$104K +$27.4K +10,114 +36%
PI
50
PFG Investments
New York
$101K – – –
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2
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