Two Sigma Advisers
MREO

Two Sigma Advisers’s Mereo BioPharma MREO Stock Holding History

Two Sigma Advisers’s Portfolio MREO Stock Details MREO Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q1 		– Sell
-251,900
Closed -$105K – 1331
2025
Q4 		$105K Buy
251,900
+9,700
+4% +$18.5K ﹤0.01% 2219
2025
Q3 		$499K Buy
242,200
+97,600
+67% +$180K ﹤0.01% 1764
2025
Q2 		$392K Buy
144,600
+115,300
+394% +$278K ﹤0.01% 1855
2025
Q1 		$65.9K Buy
+29,300
New +$82.9K ﹤0.01% 2292
2022
Q2 		– Sell
-21,100
Closed -$24K – 2802
2022
Q1 		$24K Buy
21,100
+6,000
+40% +$7.76K ﹤0.01% 2655
2021
Q4 		$24K Buy
+15,100
New +$30.2K ﹤0.01% 2540

Other funds holding MREO

RCMNY
Rubric Capital Management (New York) New York $9.44B AUM 68.42% 1-Year Est. Return
EC
EcoR1 Capital San Francisco, California $2.36B AUM 204.53% 1-Year Est. Return
6CM
683 Capital Management New York $1.92B AUM 85.52% 1-Year Est. Return
Bank of America
Bank of America Charlotte, North Carolina $1.37T AUM 24.88% 1-Year Est. Return
DCM
Defilade Capital Management Emeryville, California $712M AUM
NM
Newtyn Management New York $936M AUM 27.23% 1-Year Est. Return
Millennium Management
Millennium Management New York $240B AUM 35.51% 1-Year Est. Return
TC
Tejara Capital London, United Kingdom $303M AUM 5.43% 1-Year Est. Return
UBS Group
UBS Group Zurich, Switzerland $666B AUM 30.12% 1-Year Est. Return
WANY
Wealthspire Advisors (New York) New York $12.7B AUM 17.31% 1-Year Est. Return

Two Sigma Advisers's MREO Position: Q1 2026 in Review

Two Sigma Advisers sold out of Mereo BioPharma (MREO) in Q1 2026, closing a stake of 251,900 shares — an estimated $105K sold.

Two Sigma Advisers first reported a position in MREO in Q4 2021 and held it in 6 quarters. The position peaked at $499K in Q3 2025. 63 funds tracked by Wall St. Rank hold MREO as of Q1 2026.

  • Two Sigma Advisers reported no remaining Mereo BioPharma position as of Q1 2026 after selling out during the quarter.
  • Two Sigma Advisers sold 251,900 Mereo BioPharma shares in Q1 2026, an estimated $105K.
  • Two Sigma Advisers first reported a position in Mereo BioPharma in Q4 2021 and held it in 6 quarters.
  • Two Sigma Advisers's Mereo BioPharma position peaked at $499K in Q3 2025.
  • 63 funds tracked by Wall St. Rank held Mereo BioPharma as of Q1 2026.

Based on Two Sigma Advisers's 13F filing for Q1 2026.