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Lexicon Pharmaceuticals
LXRX

Overview Fund Activity

127 hedge funds and large institutions have $122M invested in Lexicon Pharmaceuticals in 2025 Q1 according to their latest regulatory filings, with 32 funds opening new positions, 34 increasing their positions, 32 reducing their positions, and 29 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
127
Holders Change
+1
Holders Change %
+0.79%
% of All Funds
1.73%
Holding in Top 10
1
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
0.01%
New
32
Increased
34
Reduced
32
Closed
29
Calls
$358K
Puts
$52K
Net Calls
+$306K
Net Calls Change
-$78K

Top Buyers

1
CIBC Private Wealth Group
CIBC Private Wealth Group
Georgia
$1.12M
2
UBS Group
UBS Group
Switzerland
$966K
3
AQR Capital Management
AQR Capital Management
Connecticut
$541K
4
GCP
GSA Capital Partners
United Kingdom
$372K
5
MAM
Monaco Asset Management
Monaco
$338K

Top Sellers

1
Fidelity Investments
Fidelity Investments
Massachusetts
$15.9M
2
Point72 Asset Management
Point72 Asset Management
Connecticut
$0
3
NCM
Nantahala Capital Management
Connecticut
$212K
4
NMC
NEA Management Company
Maryland
$0
5
PA
Pinnacle Associates
New York
$25K
Name Holding Trade Value Shares
Change 		Shares
Change %
Point72 Asset Management
126
Point72 Asset Management
Connecticut
– -$6.64M -8,988,421 Closed
NMC
127
NEA Management Company
Maryland
– -$1.76M -2,382,286 Closed
Wellington Management Group
128
Wellington Management Group
Massachusetts
– -$552K -747,996 Closed
Swiss National Bank
129
Swiss National Bank
Switzerland
– -$315K -426,600 Closed
VEA
130
Virtus ETF Advisers
New York
– -$314K -425,269 Closed
UBS AM
131
UBS AM
Illinois
– -$261K -353,508 Closed
WP
132
Woodline Partners
California
– -$169K -229,376 Closed
Jane Street
133
Jane Street
New York
– -$163K -220,264 Closed
Stifel Financial
134
Stifel Financial
Missouri
– -$83.3K -112,853 Closed
VF
135
Virtu Financial
New York
– -$66K -88,982 Closed
Teacher Retirement System of Texas
136
Teacher Retirement System of Texas
Texas
– -$48K -65,415 Closed
Dimensional Fund Advisors
137
Dimensional Fund Advisors
Texas
– -$48K -64,966 Closed
ASRS
138
Arizona State Retirement System
Arizona
– -$46.5K -62,976 Closed
Renaissance Technologies
139
Renaissance Technologies
New York
– -$37.8K -51,141 Closed
Canada Life
140
Canada Life
Manitoba, Canada
– -$34K -46,013 Closed
RL
141
RPO LLC
Connecticut
– -$32.7K -44,242 Closed
BCM
142
Bayesian Capital Management
New York
– -$31K -42,000 Closed
KAS
143
Kestra Advisory Services
Texas
– -$23.3K -31,500 Closed
Manulife (Manufacturers Life Insurance)
144
Manulife (Manufacturers Life Insurance)
Ontario, Canada
– -$21.9K -29,646 Closed
KK
145
KLP Kapitalforvaltning
Norway
– -$19.3K -26,200 Closed
State of Wisconsin Investment Board
146
State of Wisconsin Investment Board
Wisconsin
– -$11.1K -15,034 Closed
VWWMG
147
Vermillion & White Wealth Management Group
Pennsylvania
– -$9.91K -13,415 Closed
PWMAG
148
Pinnacle Wealth Management Advisory Group
New Jersey
– -$9.19K -12,445 Closed
ECM
149
Estabrook Capital Management
New York
– -$7.39K -10,000 Closed
NA
150
Nordwand Advisors
Pennsylvania
– -$2.95K -4,000 Closed
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