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Lexicon Pharmaceuticals

124 hedge funds and large institutions have $299M invested in Lexicon Pharmaceuticals in 2025 Q4 according to their latest regulatory filings, with 22 funds opening new positions, 29 increasing their positions, 40 reducing their positions, and 16 closing their positions.

New
Increased
Maintained
Reduced
Closed

more call options, than puts

Call options by funds: $ | Put options by funds: $

more first-time investments, than exits

New positions opened: | Existing positions closed:

more funds holding

Funds holding:

more ownership

Funds ownership:

0% more funds holding in top 10

Funds holding in top 10: 11 (0)

13% less capital invested

Capital invested by funds: $344M → $299M (-$44.9M)

28% less repeat investments, than reductions

Existing positions increased: 29 | Existing positions reduced: 40

Holders
124
Holders Change
Holders Change %
% of All Funds
Holding in Top 10
1
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
Increased
Reduced
Closed
Calls
$1.13M
Puts
$289K
Net Calls
Net Calls Change

Top Buyers

1 +$3.65M
2 +$1.74M
3 +$1.73M
4
Millennium Management
Millennium Management
New York
+$1.36M
5
Goldman Sachs
Goldman Sachs
New York
+$1.18M
Name Holding Trade Value Shares
Change
Change in
Stake
FFA
101
Farther Finance Advisors
California
$3.17K
Nisa Investment Advisors
102
Nisa Investment Advisors
Missouri
$2.98K
CIAM
103
Caitong International Asset Management
Hong Kong
$2.86K
PNC Financial Services Group
104
PNC Financial Services Group
Pennsylvania
$1.68K
PWA
105
Physician Wealth Advisors
Utah
$1.62K
RWM
106
Rialto Wealth Management
New York
$1.51K
Jones Financial Companies
107
Jones Financial Companies
Missouri
$1.27K
GRP
108
Global Retirement Partners
California
$1.15K
AW
109
Avion Wealth
Texas
$1K
FFO
110
Fortitude Family Office
Arizona
$812
Osaic Holdings
111
Osaic Holdings
Arizona
$738
SPIA
112
Steward Partners Investment Advisory
New York
$575
Northwestern Mutual Wealth Management
113
Northwestern Mutual Wealth Management
Wisconsin
$575
Rockefeller Capital Management
114
Rockefeller Capital Management
New York
$385
EWA
115
EverSource Wealth Advisors
Alabama
$182
SR
116
Syntax Research
Florida
$164
Comerica Bank
117
Comerica Bank
Texas
$140
LFG
118
Larson Financial Group
Missouri
$115
TWD
119
True Wealth Design
Ohio
$57
AAP
120
Arax Advisory Partners
Colorado
$47
BNP Paribas Financial Markets
121
BNP Paribas Financial Markets
France
$13
RhumbLine Advisers
122
RhumbLine Advisers
Massachusetts
$2
Wells Fargo
123
Wells Fargo
California
$1
Jacobs Levy Equity Management
124
Jacobs Levy Equity Management
New Jersey
CUAMC
125
China Universal Asset Management Company
China