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Lexicon Pharmaceuticals
LXRX

107 hedge funds and large institutions have $710M invested in Lexicon Pharmaceuticals in 2021 Q1 according to their latest regulatory filings, with 29 funds opening new positions, 29 increasing their positions, 29 reducing their positions, and 26 closing their positions.

New
Increased
Maintained
Reduced
Closed

90% more call options, than puts

Call options by funds: $2.58M | Put options by funds: $1.35M

70% more capital invested

Capital invested by funds: $417M → $710M (+$293M)

12% more first-time investments, than exits

New positions opened: 29 | Existing positions closed: 26

1% more funds holding

Funds holding: 106 → 107 (+1)

0% more funds holding in top 10

Funds holding in top 10: 2 → 2 (0)

0% more repeat investments, than reductions

Existing positions increased: 29 | Existing positions reduced: 29

2.25% less ownership

Funds ownership: 86.24% → 83.99% (-2.2%)

Holders
107
Holders Change
+1
Holders Change %
+0.94%
% of All Funds
1.88%
Holding in Top 10
2
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
0.04%
New
29
Increased
29
Reduced
29
Closed
26
Calls
$2.58M
Puts
$1.35M
Net Calls
+$1.22M
Net Calls Change
+$437K

Top Buyers

Rank Fund Capital Flow
1
D.E. Shaw & Co
D.E. Shaw & Co
New York
+$8.4M
2
BlackRock
BlackRock
New York
+$6.72M
3
Nomura Holdings
Nomura Holdings
Japan
+$6.36M
4
Fidelity Investments
Fidelity Investments
Massachusetts
+$5.57M
5
Two Sigma Investments
Two Sigma Investments
New York
+$3.26M

Top Sellers

Rank Fund Capital Flow
1
BI
BVF Inc
California
-$17.8M
2
Morgan Stanley
Morgan Stanley
New York
-$9.52M
3
Acadian Asset Management
Acadian Asset Management
Massachusetts
-$8.53M
4
Millennium Management
Millennium Management
New York
-$5.16M
5
Renaissance Technologies
Renaissance Technologies
New York
-$4.73M
Name Holding Trade Value Shares
Change 		Change in
Stake
Two Sigma Advisers
51
Two Sigma Advisers
New York
$379K +$447K +64,573 New
RhumbLine Advisers
52
RhumbLine Advisers
Massachusetts
$323K -$11.2K -1,611 -3%
State of Wisconsin Investment Board
53
State of Wisconsin Investment Board
Wisconsin
$321K +$378K +54,600 New
Wells Fargo
54
Wells Fargo
California
$285K -$61.5K -8,887 -15%
AllianceBernstein
55
AllianceBernstein
Tennessee
$259K -$100K -14,500 -25%
NW
56
NewEdge Wealth
Pennsylvania
$249K +$294K +42,418 New
VAS
57
Vestmark Advisory Solutions
Massachusetts
$249K +$294K +42,418 New
Barclays
58
Barclays
United Kingdom
$244K +$196K +28,248 +211%
UOTTAIMCU
59
University of Texas/Texas AM Investment Management Co (UTIMCO)
Texas
$210K – – –
EGM
60
Engineers Gate Manager
New York
$195K +$230K +33,221 New
OSAM
61
O'Shaughnessy Asset Management
Connecticut
$188K +$140K +20,225 +171%
Manulife (Manufacturers Life Insurance)
62
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$184K -$3.25K -469 -1%
New York State Common Retirement Fund
63
New York State Common Retirement Fund
New York
$171K – – –
State Board of Administration of Florida Retirement System
64
State Board of Administration of Florida Retirement System
Florida
$169K – – –
CANY
65
Caxton Associates (New York)
New York
$168K +$124K +17,958 +167%
QT
66
Quantbot Technologies
New York
$164K +$193K +27,942 New
PP
67
PDT Partners
New York
$156K +$184K +26,560 New
Jane Street
68
Jane Street
New York
$133K +$157K +22,676 New
AC
69
Athanor Capital
New York
$122K +$143K +20,713 New
Cetera Investment Advisers
70
Cetera Investment Advisers
Illinois
$121K +$143K +20,689 New
VOYA Investment Management
71
VOYA Investment Management
Georgia
$120K -$11.7K -1,686 -8%
Qube Research & Technologies (QRT)
72
Qube Research & Technologies (QRT)
United Kingdom
$120K +$142K +20,490 New
Federated Hermes
73
Federated Hermes
Pennsylvania
$114K -$80K -11,548 -37%
DTL
74
Dynamic Technology Lab
Singapore
$112K +$132K +19,084 New
Commonwealth Equity Services
75
Commonwealth Equity Services
Massachusetts
$83K – – –
1 2
3
4 5

LXRX Hedge Fund Activity: Q1 2021 in Review

107 of the 5,695 institutional investors tracked by Wall St. Rank reported a position in Lexicon Pharmaceuticals (LXRX) for Q1 2021, worth a combined $710M — up 70% from $417M a quarter earlier.

Buyers outnumbered sellers: 29 funds opened new LXRX positions and 26 closed out — a net gain of 3 holders — while 29 added to existing stakes and 29 trimmed.

The largest buyer was D.E. Shaw & Co, adding an estimated $8.4M. The largest seller was BVF Inc, cutting an estimated $17.8M.

  • 107 institutional investors held Lexicon Pharmaceuticals (LXRX) as of Q1 2021, up from 106 in Q4 2020.
  • Funds reported $710M of Lexicon Pharmaceuticals stock for Q1 2021, up 70% quarter-over-quarter.
  • 29 funds opened new Lexicon Pharmaceuticals positions in Q1 2021 and 26 closed out, a net change of +3 holders.
  • The largest Lexicon Pharmaceuticals buyer in Q1 2021 was D.E. Shaw & Co, an estimated $8.4M added.
  • The largest Lexicon Pharmaceuticals seller in Q1 2021 was BVF Inc, an estimated $17.8M sold.

Based on aggregated 13F filings for Q1 2021.