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Lexicon Pharmaceuticals
LXRX

Overview Fund Activity

122 hedge funds and large institutions have $243M invested in Lexicon Pharmaceuticals in 2025 Q2 according to their latest regulatory filings, with 28 funds opening new positions, 32 increasing their positions, 36 reducing their positions, and 33 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
122
Holders Change
-5
Holders Change %
-3.94%
% of All Funds
1.64%
Holding in Top 10
1
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
0.01%
New
28
Increased
32
Reduced
36
Closed
33
Calls
$805K
Puts
$145K
Net Calls
+$660K
Net Calls Change
+$354K

Top Buyers

1
Fidelity Investments
Fidelity Investments
Massachusetts
$36.1M
2
SC
Sessa Capital
New York
$2.84M
3
GCP
GSA Capital Partners
United Kingdom
$2.68M
4
Millennium Management
Millennium Management
New York
$1.55M
5
Jane Street
Jane Street
New York
$761K

Top Sellers

1
BlackRock
BlackRock
New York
$3.17M
2
SSA
Schonfeld Strategic Advisors
New York
$4.33M
3
State Street
State Street
Massachusetts
$774K
4
UBS Group
UBS Group
Switzerland
$379K
5
Geode Capital Management
Geode Capital Management
Massachusetts
$2.25M
Name Holding Trade Value Shares
Change 		Shares
Change %
Group One Trading
26
Group One Trading
Illinois
$328K -$18K -19,054 -5%
CLOS
27
Compagnie Lombard Odier SCmA
Switzerland
$312K +$208K +220,000 +200%
Goldman Sachs
28
Goldman Sachs
New York
$308K -$27.8K -29,406 -8%
Cerity Partners
29
Cerity Partners
New York
$195K +$33.9K +35,892 +21%
IC
30
IEQ Capital
California
$182K +$14K +14,799 +8%
IC
31
Ikarian Capital
Texas
$167K -$1.17M -1,241,473 -88%
CSS
32
Cubist Systematic Strategies
Connecticut
$150K +$137K +144,407 +1,047%
JG
33
Jain Global
New York
$144K +$144K +151,813 New
VF
34
Virtu Financial
New York
$139K +$139K +146,805 New
Morgan Stanley
35
Morgan Stanley
New York
$124K -$483K -510,236 -80%
ACM
36
Aster Capital Management
United Arab Emirates
$123K +$123K +130,452 New
Carson Wealth (CWM LLC)
37
Carson Wealth (CWM LLC)
Nebraska
$103K +$3.6K +3,826 +4%
LPL Financial
38
LPL Financial
California
$98.8K +$31.7K +33,476 +47%
Bank of Montreal
39
Bank of Montreal
Ontario, Canada
$94.6K – – –
Squarepoint
40
Squarepoint
New York
$90.4K -$94.4K -99,792 -51%
Commonwealth Equity Services
41
Commonwealth Equity Services
Massachusetts
$86K – – –
QC
42
Quantessence Capital
New York
$79.5K +$79.5K +84,098 New
CUAMC
43
China Universal Asset Management Company
China
$69K +$410 +434 +0.6%
Wealth Enhancement Advisory Services
44
Wealth Enhancement Advisory Services
Minnesota
$67.1K +$4.73K +5,247 +8%
PAS
45
Point72 Asia (Singapore)
Singapore
$66.2K -$95.6K -101,102 -59%
SC
46
Savant Capital
Illinois
$65.8K +$16.4K +17,348 +33%
XT
47
XTX Topco
Cayman Islands
$62.7K +$50.9K +53,805 +431%
FGA
48
Fortis Group Advisors
New Jersey
$61.8K +$21.4K +20,000 +53%
VPIM
49
Vanguard Personalized Indexing Management
California
$61.8K +$27K +28,594 +78%
SPWM
50
Straight Path Wealth Management
Michigan
$59.3K – – –
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