|
1
|
Fidelity Investments
Boston,
Massachusetts
|
$770M
|
-$197M
|
-3,107,454
|
-20%
|
|
|
2
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$650M
|
+$70.6M
|
+1,114,848
|
+12%
|
|
|
3
|
RA Capital Management
Boston,
Massachusetts
|
$377M
|
–
|
–
|
–
|
|
|
4
|
HHLR Advisors
Grand Cayman,
Cayman Islands
|
$360M
|
-$28.6M
|
-451,983
|
-7%
|
|
|
5
|
|
$317M
|
+$40.9M
|
+645,154
|
+14%
|
|
|
6
|
Capital World Investors
Los Angeles,
California
|
$144M
|
-$119K
|
-1,872
|
-0.1%
|
|
|
7
|
Wellington Management Group
Boston,
Massachusetts
|
$139M
|
+$61M
|
+962,381
|
+72%
|
|
|
8
|
Massachusetts Financial Services
Boston,
Massachusetts
|
$119M
|
+$7.46M
|
+117,794
|
+6%
|
|
|
9
|
Paradigm Biocapital Advisors
New York
|
$114M
|
-$8.29M
|
-130,836
|
-6%
|
|
|
10
|
Janus Henderson Group
London,
|
$112M
|
+$8.33M
|
+131,379
|
+8%
|
|
|
11
|
Capital International Investors
Los Angeles,
California
|
$110M
|
-$514K
|
-8,116
|
-0.4%
|
|
|
12
|
|
$107M
|
+$62.3M
|
+983,329
|
+123%
|
|
|
13
|
Westfield Capital Management
Boston,
Massachusetts
|
$107M
|
+$6.85M
|
+108,097
|
+6%
|
|
|
14
|
Holocene Advisors
New York
|
$106M
|
+$31.1M
|
+491,433
|
+39%
|
|
|
15
|
Federated Hermes
Pittsburgh,
Pennsylvania
|
$104M
|
-$2.44M
|
-38,524
|
-2%
|
|
|
16
|
Polar Capital Holdings
London,
United Kingdom
|
$82.5M
|
-$31.8M
|
-501,642
|
-27%
|
|
|
17
|
AllianceBernstein
Nashville,
Tennessee
|
$71.4M
|
+$5.33M
|
+84,076
|
+8%
|
|
|
18
|
TimesSquare Capital Management
New York
|
$64.1M
|
+$9.01M
|
+142,118
|
+15%
|
|
|
19
|
ArrowMark Colorado Holdings
Denver,
Colorado
|
$64.1M
|
-$617K
|
-9,729
|
-0.9%
|
|
|
20
|
State Street
Boston,
Massachusetts
|
$62.4M
|
+$10.8M
|
+171,159
|
+20%
|
|
|
21
|
Johnson & Johnson
New Brunswick,
New Jersey
|
$49M
|
–
|
–
|
–
|
|
|
22
|
Matthews International Capital Management
San Francisco,
California
|
$48.7M
|
-$19.9M
|
-314,254
|
-28%
|
|
|
23
|
Avidity Partners Management
Dallas,
Texas
|
$41.2M
|
-$17.9M
|
-282,000
|
-29%
|
|
|
24
|
PFM Health Sciences
San Francisco,
California
|
$40.9M
|
–
|
–
|
–
|
|
|
25
|
Adage Capital Partners
Boston,
Massachusetts
|
$37M
|
-$69.3M
|
-1,093,510
|
-64%
|
|
