|
1
|
Fidelity Investments
Boston,
Massachusetts
|
$1.18B
|
+$42.5M
|
+650,821
|
+4%
|
|
|
2
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$623M
|
+$519M
|
+7,939,175
|
+727%
|
|
|
3
|
HHLR Advisors
Grand Cayman,
Cayman Islands
|
$444M
|
+$85.3M
|
+1,306,166
|
+25%
|
|
|
4
|
RA Capital Management
Boston,
Massachusetts
|
$432M
|
+$250M
|
+3,828,484
|
+157%
|
|
|
5
|
|
$327M
|
+$40.2M
|
+615,641
|
+15%
|
|
|
6
|
Capital World Investors
Los Angeles,
California
|
$165M
|
-$91K
|
-1,392
|
-0.1%
|
|
|
7
|
Federated Hermes
Pittsburgh,
Pennsylvania
|
$134M
|
-$26M
|
-397,284
|
-17%
|
|
|
8
|
Polar Capital Holdings
London,
United Kingdom
|
$129M
|
-$6.76M
|
-103,513
|
-5%
|
|
|
9
|
Capital International Investors
Los Angeles,
California
|
$129M
|
-$5.79M
|
-88,675
|
-5%
|
|
|
10
|
Janus Henderson Group
London,
|
$125M
|
-$8.15M
|
-124,754
|
-6%
|
|
|
11
|
Paradigm Biocapital Advisors
New York
|
$125M
|
+$19.3M
|
+295,393
|
+20%
|
|
|
12
|
Wellington Management Group
Boston,
Massachusetts
|
$114M
|
-$6.51M
|
-99,577
|
-6%
|
|
|
13
|
Massachusetts Financial Services
Boston,
Massachusetts
|
$114M
|
+$9.24M
|
+141,479
|
+9%
|
|
|
14
|
AllianceBernstein
Nashville,
Tennessee
|
$99.5M
|
-$8.96M
|
-137,055
|
-9%
|
|
|
15
|
Matthews International Capital Management
San Francisco,
California
|
$77.6M
|
-$12M
|
-182,976
|
-14%
|
|
|
16
|
ArrowMark Colorado Holdings
Denver,
Colorado
|
$74.2M
|
+$181K
|
+2,777
|
+0.3%
|
|
|
17
|
Westfield Capital Management
Boston,
Massachusetts
|
$67.1M
|
+$63.5M
|
+972,054
|
New
|
|
|
18
|
TimesSquare Capital Management
New York
|
$63.4M
|
-$9.45M
|
-144,618
|
-14%
|
|
|
19
|
Holocene Advisors
New York
|
$62.6M
|
+$59.3M
|
+907,053
|
New
|
|
|
20
|
State Street
Boston,
Massachusetts
|
$61.8M
|
-$2.93M
|
-44,895
|
-5%
|
|
|
21
|
|
$61.3M
|
+$30M
|
+459,610
|
+107%
|
|
|
22
|
Adage Capital Partners
Boston,
Massachusetts
|
$58.5M
|
+$55.4M
|
+848,100
|
New
|
|
|
23
|
Johnson & Johnson
New Brunswick,
New Jersey
|
$56.2M
|
-$53.2M
|
-814,587
|
-50%
|
|
|
24
|
Avidity Partners Management
Dallas,
Texas
|
$55.1M
|
-$21M
|
-321,600
|
-29%
|
|
|
25
|
PFM Health Sciences
San Francisco,
California
|
$46.9M
|
+$13.5M
|
+206,915
|
+44%
|
|
