|
1
|
Fidelity Investments
Boston,
Massachusetts
|
$756M
|
+$124M
|
+2,563,545
|
+20%
|
|
|
2
|
HHLR Advisors
Grand Cayman,
Cayman Islands
|
$256M
|
–
|
–
|
–
|
|
|
3
|
|
$194M
|
+$7.07M
|
+146,025
|
+4%
|
|
|
4
|
RA Capital Management
Boston,
Massachusetts
|
$122M
|
+$4.73M
|
+97,613
|
+4%
|
|
|
5
|
Capital World Investors
Los Angeles,
California
|
$119M
|
+$15.5K
|
+319
|
+0%
|
|
|
6
|
Federated Hermes
Pittsburgh,
Pennsylvania
|
$117M
|
–
|
–
|
–
|
|
|
7
|
Capital International Investors
Los Angeles,
California
|
$108M
|
-$34.6M
|
-713,286
|
-25%
|
|
|
8
|
Janus Henderson Group
London,
|
$92.2M
|
-$90.9M
|
-1,877,106
|
-50%
|
|
|
9
|
Wellington Management Group
Boston,
Massachusetts
|
$90.5M
|
+$7.74M
|
+159,785
|
+10%
|
|
|
10
|
Johnson & Johnson
New Brunswick,
New Jersey
|
$81.3M
|
–
|
–
|
–
|
|
|
11
|
AllianceBernstein
Nashville,
Tennessee
|
$64.5M
|
-$11.8M
|
-244,573
|
-16%
|
|
|
12
|
Matthews International Capital Management
San Francisco,
California
|
$58.5M
|
-$14.3M
|
-294,685
|
-20%
|
|
|
13
|
Artisan Partners
Milwaukee,
Wisconsin
|
$53.2M
|
-$16.5M
|
-341,244
|
-24%
|
|
|
14
|
Polar Capital Holdings
London,
United Kingdom
|
$53M
|
+$332K
|
+6,850
|
+0.6%
|
|
|
15
|
Paradigm Biocapital Advisors
New York
|
$52.7M
|
-$1.05M
|
-21,721
|
-2%
|
|
|
16
|
ArrowMark Colorado Holdings
Denver,
Colorado
|
$51.7M
|
+$909K
|
+18,753
|
+2%
|
|
|
17
|
Massachusetts Financial Services
Boston,
Massachusetts
|
$51.1M
|
+$49.6M
|
+1,024,009
|
New
|
|
|
18
|
Avidity Partners Management
Dallas,
Texas
|
$48.4M
|
+$47M
|
+970,000
|
New
|
|
|
19
|
TimesSquare Capital Management
New York
|
$47.2M
|
+$252K
|
+5,200
|
+0.6%
|
|
|
20
|
State Street
Boston,
Massachusetts
|
$40M
|
+$1.67M
|
+34,548
|
+5%
|
|
|
21
|
Farallon Capital Management
San Francisco,
California
|
$37.3M
|
+$24.7M
|
+508,900
|
+214%
|
|
|
22
|
Braidwell
Stamford,
Connecticut
|
$32.9M
|
+$31.9M
|
+658,101
|
New
|
|
|
23
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$32.7M
|
-$62K
|
-1,279
|
-0.2%
|
|
|
24
|
Capital International Inc
Los Angeles,
California
|
$28M
|
-$33.1M
|
-683,485
|
-55%
|
|
|
25
|
Manulife (Manufacturers Life Insurance)
Canada,
Ontario, Canada
|
$25.4M
|
+$270K
|
+5,579
|
+1%
|
|
