|
1
|
Capital International Investors
Los Angeles,
California
|
$110M
|
+$68.6M
|
+2,019,833
|
+303%
|
|
|
2
|
Federated Hermes
Pittsburgh,
Pennsylvania
|
$82.6M
|
-$3.14M
|
-92,339
|
-4%
|
|
|
3
|
Capital International Inc
Los Angeles,
California
|
$80.1M
|
+$1.19M
|
+35,000
|
+2%
|
|
|
4
|
AllianceBernstein
Nashville,
Tennessee
|
$77.9M
|
-$7.59M
|
-223,308
|
-11%
|
|
|
5
|
Hudson Bay Capital Management
Stamford,
Connecticut
|
$77.1M
|
-$9.82M
|
-288,900
|
-13%
|
|
|
6
|
Baker Bros. Advisors
New York
|
$68.3M
|
+$52.6M
|
+1,548,908
|
+1,340%
|
|
|
7
|
Consonance Capital Management
New York
|
$67.6M
|
+$25.5M
|
+750,889
|
+84%
|
|
|
8
|
Johnson & Johnson Innovation - JJDC
New Brunswick,
New Jersey
|
$66.9M
|
–
|
–
|
–
|
|
|
9
|
Matthews International Capital Management
San Francisco,
California
|
$55.1M
|
+$9.8M
|
+288,200
|
+27%
|
|
|
10
|
Capital World Investors
Los Angeles,
California
|
$49M
|
–
|
–
|
–
|
|
|
11
|
Artisan Partners
Milwaukee,
Wisconsin
|
$41.1M
|
+$5.27M
|
+155,199
|
+18%
|
|
|
12
|
RA Capital Management
Boston,
Massachusetts
|
$40.1M
|
+$33.2M
|
+977,503
|
New
|
|
|
13
|
Vivo Capital
Palo Alto,
California
|
$39.3M
|
-$61.1M
|
-1,798,305
|
-65%
|
|
|
14
|
|
$32.9M
|
+$20.2M
|
+593,618
|
+284%
|
|
|
15
|
HHLR Advisors
Grand Cayman,
Cayman Islands
|
$26.7M
|
–
|
–
|
–
|
|
|
16
|
Avidity Partners Management
Dallas,
Texas
|
$25.7M
|
+$21.2M
|
+625,000
|
New
|
|
|
17
|
FengHe Fund Management
Singapore
|
$21.6M
|
+$5.2M
|
+153,083
|
+41%
|
|
|
18
|
Franklin Resources
San Mateo,
California
|
$20.4M
|
–
|
–
|
–
|
|
|
19
|
Marshall Wace North America
New York
|
$19M
|
+$1.76M
|
+51,688
|
+13%
|
|
|
20
|
Bellevue Group
Kuesnacht,
Switzerland
|
$16M
|
-$7.24M
|
-213,080
|
-35%
|
|
|
21
|
Manulife (Manufacturers Life Insurance)
Canada,
Ontario, Canada
|
$13.5M
|
–
|
–
|
–
|
|
|
22
|
Rock Springs Capital Management
Baltimore,
Maryland
|
$12.8M
|
–
|
–
|
–
|
|
|
23
|
Novo Holdings A/S
Hellerup,
Denmark
|
$11.5M
|
+$867K
|
+25,500
|
+10%
|
|
|
24
|
Woodline Partners
San Francisco,
California
|
$11.2M
|
+$9.28M
|
+273,043
|
New
|
|
|
25
|
Capital International Sarl
Los Angeles,
California
|
$9.05M
|
+$1.63M
|
+47,924
|
+28%
|
|
