|
1
|
Fidelity Investments
Boston,
Massachusetts
|
$779M
|
+$1.15M
|
+6,818
|
+0.2%
|
|
|
2
|
|
$711M
|
-$15.3M
|
-90,707
|
-2%
|
|
|
3
|
Vanguard Group
Malvern,
Pennsylvania
|
$509M
|
-$8.94M
|
-53,169
|
-2%
|
|
|
4
|
Avoro Capital Advisors
New York
|
$492M
|
+$17.2M
|
+102,178
|
+4%
|
|
|
5
|
State Street
Boston,
Massachusetts
|
$221M
|
-$8.79M
|
-52,268
|
-4%
|
|
|
6
|
Capital World Investors
Los Angeles,
California
|
$172M
|
+$12.7M
|
+75,265
|
+9%
|
|
|
7
|
Redmile Group
San Francisco,
California
|
$133M
|
-$2.61M
|
-15,500
|
-2%
|
|
|
8
|
Frazier Life Sciences Management
Palo Alto,
California
|
$124M
|
-$16.8M
|
-100,000
|
-13%
|
|
|
9
|
Geode Capital Management
Boston,
Massachusetts
|
$110M
|
+$3.49M
|
+20,757
|
+4%
|
|
|
10
|
|
$104M
|
+$61.4M
|
+365,304
|
+174%
|
|
|
11
|
Dimensional Fund Advisors
Austin,
Texas
|
$96.3M
|
-$9.2M
|
-54,680
|
-9%
|
|
|
12
|
Hood River Capital Management
Palm Beach Gardens,
Florida
|
$94.6M
|
+$2M
|
+11,918
|
+2%
|
|
|
13
|
Soleus Capital Management
Greenwich,
Connecticut
|
$79.6M
|
+$14M
|
+83,379
|
+23%
|
|
|
14
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$74.1M
|
-$16.6M
|
-98,598
|
-19%
|
|
|
15
|
Braidwell
Stamford,
Connecticut
|
$72.3M
|
+$33.7M
|
+200,244
|
+100%
|
|
|
16
|
|
$53.8M
|
+$7.05M
|
+41,930
|
+16%
|
|
|
17
|
|
$49.3M
|
+$9.03M
|
+53,681
|
+24%
|
|
|
18
|
Northern Trust
Chicago,
Illinois
|
$46.9M
|
-$381K
|
-2,268
|
-0.9%
|
|
|
19
|
|
$45.9M
|
-$3.48M
|
-20,709
|
-8%
|
|
|
20
|
Charles Schwab
San Francisco,
California
|
$45.2M
|
+$1.24M
|
+7,344
|
+3%
|
|
|
21
|
Nuveen
Charlotte,
North Carolina
|
$42.2M
|
-$11.8M
|
-69,935
|
-23%
|
|
|
22
|
|
$42.1M
|
-$7.32M
|
-43,535
|
-16%
|
|
|
23
|
Woodline Partners
San Francisco,
California
|
$40M
|
+$158K
|
+941
|
+0.4%
|
|
|
24
|
T. Rowe Price Investment Management
Baltimore,
Maryland
|
$33.5M
|
+$31.2M
|
+185,550
|
New
|
|
|
25
|
Bank of New York Mellon
New York
|
$30.5M
|
-$28.1K
|
-167
|
-0.1%
|
|
