|
1
|
Fidelity Investments
Boston,
Massachusetts
|
$755M
|
+$258M
|
+1,857,994
|
+78%
|
|
|
2
|
Avoro Capital Advisors
New York
|
$455M
|
-$1.39M
|
-10,000
|
-0.4%
|
|
|
3
|
Vanguard Group
Malvern,
Pennsylvania
|
$433M
|
-$416K
|
-2,995
|
-0.1%
|
|
|
4
|
|
$321M
|
-$579K
|
-4,168
|
-0.2%
|
|
|
5
|
Redmile Group
San Francisco,
California
|
$268M
|
-$31.2M
|
-224,939
|
-13%
|
|
|
6
|
Frazier Life Sciences Management
Palo Alto,
California
|
$176M
|
–
|
–
|
–
|
|
|
7
|
State Street
Boston,
Massachusetts
|
$168M
|
-$40.7M
|
-292,950
|
-24%
|
|
|
8
|
Jennison Associates
New York
|
$119M
|
-$7.45M
|
-53,609
|
-7%
|
|
|
9
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$117M
|
+$32.1M
|
+231,255
|
+54%
|
|
|
10
|
Dimensional Fund Advisors
Austin,
Texas
|
$102M
|
+$3.07M
|
+22,109
|
+4%
|
|
|
11
|
Geode Capital Management
Boston,
Massachusetts
|
$93.6M
|
+$2.01M
|
+14,499
|
+3%
|
|
|
12
|
Hood River Capital Management
Palm Beach Gardens,
Florida
|
$88.2M
|
+$5.15M
|
+37,073
|
+8%
|
|
|
13
|
Lord, Abbett & Co
Jersey City,
New Jersey
|
$87.6M
|
-$17.5M
|
-126,226
|
-20%
|
|
|
14
|
|
$77.3M
|
+$28.7M
|
+206,521
|
+91%
|
|
|
15
|
Nuveen
Charlotte,
North Carolina
|
$58.8M
|
+$2.08M
|
+14,977
|
+5%
|
|
|
16
|
Credit Suisse
Zurich,
Switzerland
|
$57.3M
|
-$21.2M
|
-152,538
|
-32%
|
|
|
17
|
Woodline Partners
San Francisco,
California
|
$49M
|
-$28.7M
|
-206,524
|
-43%
|
|
|
18
|
|
$38.9M
|
-$14M
|
-100,892
|
-32%
|
|
|
19
|
Skandinaviska Enskilda Banken (SEB)
Stockholm,
Sweden
|
$38.7M
|
-$3.66M
|
-26,314
|
-11%
|
|
|
20
|
Northern Trust
Chicago,
Illinois
|
$36.5M
|
-$572K
|
-4,121
|
-2%
|
|
|
21
|
Charles Schwab
San Francisco,
California
|
$33.6M
|
+$537K
|
+3,865
|
+2%
|
|
|
22
|
Braidwell
Stamford,
Connecticut
|
$31.5M
|
-$2.65M
|
-19,111
|
-10%
|
|
|
23
|
|
$31.2M
|
-$5.33M
|
-38,393
|
-18%
|
|
|
24
|
Baker Bros. Advisors
New York
|
$30.2M
|
–
|
–
|
–
|
|
|
25
|
Allspring Global Investments
Charlotte,
North Carolina
|
$28.2M
|
+$13.8M
|
+99,101
|
+167%
|
|
