|
1
|
Fidelity Investments
Boston,
Massachusetts
|
$781M
|
+$1.76M
|
+9,115
|
+0.2%
|
|
|
2
|
|
$727M
|
+$8.73M
|
+45,278
|
+1%
|
|
|
3
|
Vanguard Group
Malvern,
Pennsylvania
|
$519M
|
-$3.74M
|
-19,392
|
-0.7%
|
|
|
4
|
Avoro Capital Advisors
New York
|
$477M
|
+$36.5M
|
+189,222
|
+8%
|
|
|
5
|
State Street
Boston,
Massachusetts
|
$264M
|
+$23.1M
|
+119,936
|
+9%
|
|
|
6
|
Frazier Life Sciences Management
Palo Alto,
California
|
$180M
|
–
|
–
|
–
|
|
|
7
|
Capital World Investors
Los Angeles,
California
|
$160M
|
+$178K
|
+925
|
+0.1%
|
|
|
8
|
Redmile Group
San Francisco,
California
|
$147M
|
-$40.7M
|
-210,833
|
-21%
|
|
|
9
|
Dimensional Fund Advisors
Austin,
Texas
|
$109M
|
+$3.82M
|
+19,809
|
+3%
|
|
|
10
|
Geode Capital Management
Boston,
Massachusetts
|
$108M
|
+$2.2M
|
+11,411
|
+2%
|
|
|
11
|
Hood River Capital Management
Palm Beach Gardens,
Florida
|
$91.4M
|
-$3.66M
|
-18,989
|
-4%
|
|
|
12
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$79.8M
|
-$31.2M
|
-161,886
|
-27%
|
|
|
13
|
Jennison Associates
New York
|
$74.6M
|
-$21.3M
|
-110,333
|
-21%
|
|
|
14
|
|
$66.5M
|
+$17.4M
|
+90,474
|
+33%
|
|
|
15
|
Nuveen
Charlotte,
North Carolina
|
$56.8M
|
-$4.69M
|
-24,315
|
-7%
|
|
|
16
|
|
$54.9M
|
-$23.3M
|
-120,977
|
-29%
|
|
|
17
|
Lord, Abbett & Co
Jersey City,
New Jersey
|
$51.7M
|
-$20.8M
|
-108,079
|
-28%
|
|
|
18
|
|
$50.2M
|
-$8.2M
|
-42,523
|
-13%
|
|
|
19
|
|
$44.4M
|
+$44.9M
|
+232,757
|
+2,053%
|
|
|
20
|
Franklin Resources
San Mateo,
California
|
$43.8M
|
+$12M
|
+62,178
|
+34%
|
|
|
21
|
Charles Schwab
San Francisco,
California
|
$43.7M
|
+$3.81M
|
+19,777
|
+9%
|
|
|
22
|
Northern Trust
Chicago,
Illinois
|
$43.4M
|
+$3.9M
|
+20,230
|
+9%
|
|
|
23
|
|
$40.9M
|
-$5.17M
|
-26,817
|
-11%
|
|
|
24
|
Soleus Capital Management
Greenwich,
Connecticut
|
$39.5M
|
+$17.5M
|
+90,979
|
+72%
|
|
|
25
|
Woodline Partners
San Francisco,
California
|
$32.7M
|
-$21.6M
|
-112,103
|
-38%
|
|
