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Krystal Biotech

334 hedge funds and large institutions have $7.02B invested in Krystal Biotech in 2025 Q4 according to their latest regulatory filings, with 82 funds opening new positions, 112 increasing their positions, 104 reducing their positions, and 27 closing their positions.

New
Increased
Maintained
Reduced
Closed

204% more first-time investments, than exits

New positions opened: 82 | Existing positions closed: 27

145% more call options, than puts

Call options by funds: $53M | Put options by funds: $21.6M

42% more capital invested

Capital invested by funds: $4.94B → $7.02B (+$2.08B)

18% more funds holding

Funds holding: 284334 (+50)

14% more funds holding in top 10

Funds holding in top 10: 78 (+1)

1.39% more ownership

Funds ownership: 96.77%98.16% (+1.4%)

8% more repeat investments, than reductions

Existing positions increased: 112 | Existing positions reduced: 104

Holders
334
Holders Change
+50
Holders Change %
+17.61%
% of All Funds
4.06%
Holding in Top 10
8
Holding in Top 10 Change
+1
Holding in Top 10 Change %
+14.29%
% of All Funds
0.1%
New
82
Increased
112
Reduced
104
Closed
27
Calls
$53M
Puts
$21.6M
Net Calls
+$31.3M
Net Calls Change
+$104M
Name Holding Trade Value Shares
Change
Change in
Stake
SPS
151
Susquehanna Portfolio Strategies
Pennsylvania
$1.01M +$68.4K +325 +9%
SFCM
152
Seven Fleet Capital Management
California
$986K +$842K +4,000 New
P8IP
153
Pier 88 Investment Partners
California
$979K +$31.6K +150 +4%
Zurich Cantonal Bank
154
Zurich Cantonal Bank
Switzerland
$953K
Fisher Asset Management
155
Fisher Asset Management
Washington
$933K +$797K +3,786 New
MSRPS
156
Maryland State Retirement & Pension System
Maryland
$930K +$14.5K +69 +2%
Amundi
157
Amundi
France
$926K -$170K -807 -18%
BFM
158
Boothbay Fund Management
New York
$870K -$1.13M -5,362 -60%
Renaissance Technologies
159
Renaissance Technologies
New York
$814K +$695K +3,300 New
Teacher Retirement System of Texas
160
Teacher Retirement System of Texas
Texas
$794K -$444K -2,109 -40%
William Blair & Company
161
William Blair & Company
Illinois
$783K -$331K -1,575 -33%
BBA
162
Baader Bank Aktiengesellschaft
Germany
$769K +$666K +3,163 New
DnB Asset Management
163
DnB Asset Management
Norway
$763K +$155K +737 +31%
RAM
164
Resona Asset Management
Japan
$754K
OL
165
Odyssean LLC
Connecticut
$743K +$634K +3,014 New
CWS
166
Confluence Wealth Services
Pennsylvania
$720K
N
167
Natixis
France
$720K +$589K +2,798 +2,293%
QCM
168
Quantinno Capital Management
New York
$716K +$156K +742 +34%
BHCM
169
Brevan Howard Capital Management
Jersey
$715K +$611K +2,902 New
OF
170
Optimize Financial
California
$704K +$8.42K +40 +1%
VIA
171
Virtus Investment Advisers
Connecticut
$688K -$78.9K -375 -12%
ET
172
Entropy Technologies
New York
$617K +$527K +2,503 New
OSAM
173
O'Shaughnessy Asset Management
Connecticut
$597K +$197K +938 +63%
CG
174
Cynosure Group
Utah
$593K -$739K -3,512 -59%
Janney Montgomery Scott
175
Janney Montgomery Scott
Pennsylvania
$591K -$38.3K -182 -7%