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Krystal Biotech

332 hedge funds and large institutions have $7.01B invested in Krystal Biotech in 2025 Q4 according to their latest regulatory filings, with 81 funds opening new positions, 111 increasing their positions, 105 reducing their positions, and 27 closing their positions.

New
Increased
Maintained
Reduced
Closed

more first-time investments, than exits

New positions opened: | Existing positions closed:

more call options, than puts

Call options by funds: $ | Put options by funds: $

more capital invested

Capital invested by funds: $ → $

more funds holding

Funds holding:

14% more funds holding in top 10

Funds holding in top 10: 78 (+1)

1.26% more ownership

Funds ownership: 96.77%98.03% (+1.3%)

6% more repeat investments, than reductions

Existing positions increased: 111 | Existing positions reduced: 105

Holders
332
Holders Change
Holders Change %
% of All Funds
Holding in Top 10
8
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
Increased
Reduced
Closed
Calls
$53M
Puts
$21.6M
Net Calls
Net Calls Change

Top Buyers

1 +$86.1M
2 +$47.8M
3 +$44.1M
4
ACA
Avoro Capital Advisors
New York
+$23.4M
5
Franklin Resources
Franklin Resources
California
+$22.3M

Top Sellers

1 -$67M
2 -$52.7M
3 -$42.1M
4
UBS AM
UBS AM
Illinois
-$35.6M
5
Millennium Management
Millennium Management
New York
-$28.2M
Name Holding Trade Value Shares
Change
Change in
Stake
EI
76
EFG International
$5.82M
Deutsche Bank
77
Deutsche Bank
Germany
$5.53M
Canada Life
78
Canada Life
Manitoba, Canada
$5.45M
EC
79
Elmind Capital
New York
$5.42M
California State Teachers Retirement System (CalSTRS)
80
California State Teachers Retirement System (CalSTRS)
California
$5.07M
Bessemer Group
81
Bessemer Group
New Jersey
$5M
ACM
82
ADAR1 Capital Management
Texas
$4.93M
GKIM
83
GW&K Investment Management
Massachusetts
$4.83M
SG Americas Securities
84
SG Americas Securities
New York
$4.66M
Fiera Capital (Canada)
85
Fiera Capital (Canada)
Quebec, Canada
$4.65M
SOADOR
86
State of Alaska Department of Revenue
Alaska
$4.41M
Thrivent Financial for Lutherans
87
Thrivent Financial for Lutherans
Minnesota
$4.37M
1832 Asset Management
88
1832 Asset Management
Ontario, Canada
$4.34M
PA
89
Perceptive Advisors
New York
$4.31M
DC
90
Decheng Capital
California
$4.27M
PFPG
91
Pinnacle Financial Partners (Georgia)
Georgia
$4.19M
Verition Fund Management
92
Verition Fund Management
Connecticut
$4.18M
ETCM
93
Evolutionary Tree Capital Management
Virginia
$4.14M
State Board of Administration of Florida Retirement System
94
State Board of Administration of Florida Retirement System
Florida
$3.88M
New York State Teachers Retirement System (NYSTRS)
95
New York State Teachers Retirement System (NYSTRS)
New York
$3.86M
IC
96
Ikarian Capital
Texas
$3.65M
Millennium Management
97
Millennium Management
New York
$3.61M
State of Wisconsin Investment Board
98
State of Wisconsin Investment Board
Wisconsin
$3.57M
AQR Capital Management
99
AQR Capital Management
Connecticut
$3.49M
Creative Planning
100
Creative Planning
Kansas
$3.42M