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Krystal Biotech

334 hedge funds and large institutions have $7.02B invested in Krystal Biotech in 2025 Q4 according to their latest regulatory filings, with 82 funds opening new positions, 112 increasing their positions, 104 reducing their positions, and 27 closing their positions.

New
Increased
Maintained
Reduced
Closed

204% more first-time investments, than exits

New positions opened: 82 | Existing positions closed: 27

145% more call options, than puts

Call options by funds: $53M | Put options by funds: $21.6M

42% more capital invested

Capital invested by funds: $4.94B → $7.02B (+$2.08B)

18% more funds holding

Funds holding: 284334 (+50)

14% more funds holding in top 10

Funds holding in top 10: 78 (+1)

1.39% more ownership

Funds ownership: 96.77%98.16% (+1.4%)

8% more repeat investments, than reductions

Existing positions increased: 112 | Existing positions reduced: 104

Holders
334
Holders Change
+50
Holders Change %
+17.61%
% of All Funds
4.06%
Holding in Top 10
8
Holding in Top 10 Change
+1
Holding in Top 10 Change %
+14.29%
% of All Funds
0.1%
New
82
Increased
112
Reduced
104
Closed
27
Calls
$53M
Puts
$21.6M
Net Calls
+$31.3M
Net Calls Change
+$104M
Name Holding Trade Value Shares
Change
Change in
Stake
EI
76
EFG International
$5.82M +$4.96M +23,569 New
Deutsche Bank
77
Deutsche Bank
Germany
$5.53M +$225K +1,071 +5%
Canada Life
78
Canada Life
Manitoba, Canada
$5.45M +$145K +689 +3%
EC
79
Elmind Capital
New York
$5.42M +$4.63M +22,000 New
California State Teachers Retirement System (CalSTRS)
80
California State Teachers Retirement System (CalSTRS)
California
$5.07M -$62.9K -299 -1%
Bessemer Group
81
Bessemer Group
New Jersey
$5M +$4.23M +20,111 +13,497%
ACM
82
ADAR1 Capital Management
Texas
$4.93M +$314K +1,491 +8%
GKIM
83
GW&K Investment Management
Massachusetts
$4.83M +$1.91M +9,089 +87%
SG Americas Securities
84
SG Americas Securities
New York
$4.66M +$3.28M +15,591 +470%
Fiera Capital (Canada)
85
Fiera Capital (Canada)
Quebec, Canada
$4.65M +$799K +3,794 +25%
SOADOR
86
State of Alaska Department of Revenue
Alaska
$4.41M +$764K +3,628 +25%
Thrivent Financial for Lutherans
87
Thrivent Financial for Lutherans
Minnesota
$4.37M -$179K -850 -5%
1832 Asset Management
88
1832 Asset Management
Ontario, Canada
$4.34M +$3.7M +17,600 New
PA
89
Perceptive Advisors
New York
$4.31M -$3.68M -17,500 -50%
DC
90
Decheng Capital
California
$4.27M -$3.16M -15,000 -46%
PFPG
91
Pinnacle Financial Partners (Georgia)
Georgia
$4.19M +$3.57M +16,983 New
Verition Fund Management
92
Verition Fund Management
Connecticut
$4.18M -$3.02M -14,364 -46%
ETCM
93
Evolutionary Tree Capital Management
Virginia
$4.14M +$916K +4,350 +35%
State Board of Administration of Florida Retirement System
94
State Board of Administration of Florida Retirement System
Florida
$3.88M +$2.1M +9,971 +172%
New York State Teachers Retirement System (NYSTRS)
95
New York State Teachers Retirement System (NYSTRS)
New York
$3.86M +$21K +100 +0.6%
IC
96
Ikarian Capital
Texas
$3.65M -$2.02M -9,607 -39%
Millennium Management
97
Millennium Management
New York
$3.61M -$28.2M -134,055 -90%
State of Wisconsin Investment Board
98
State of Wisconsin Investment Board
Wisconsin
$3.57M -$3.13M -14,874 -51%
AQR Capital Management
99
AQR Capital Management
Connecticut
$3.49M -$1.26M -5,976 -30%
Creative Planning
100
Creative Planning
Kansas
$3.42M +$478K +2,272 +20%