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Krystal Biotech

332 hedge funds and large institutions have $7.01B invested in Krystal Biotech in 2025 Q4 according to their latest regulatory filings, with 81 funds opening new positions, 111 increasing their positions, 105 reducing their positions, and 27 closing their positions.

New
Increased
Maintained
Reduced
Closed

more first-time investments, than exits

New positions opened: | Existing positions closed:

more call options, than puts

Call options by funds: $ | Put options by funds: $

more capital invested

Capital invested by funds: $ → $

more funds holding

Funds holding:

14% more funds holding in top 10

Funds holding in top 10: 78 (+1)

1.26% more ownership

Funds ownership: 96.77%98.03% (+1.3%)

6% more repeat investments, than reductions

Existing positions increased: 111 | Existing positions reduced: 105

Holders
332
Holders Change
Holders Change %
% of All Funds
Holding in Top 10
8
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
Increased
Reduced
Closed
Calls
$53M
Puts
$21.6M
Net Calls
Net Calls Change

Top Buyers

1 +$86.1M
2 +$47.8M
3 +$44.1M
4
ACA
Avoro Capital Advisors
New York
+$23.4M
5
Franklin Resources
Franklin Resources
California
+$22.3M

Top Sellers

1 -$67M
2 -$52.7M
3 -$42.1M
4
UBS AM
UBS AM
Illinois
-$35.6M
5
Millennium Management
Millennium Management
New York
-$28.2M
Name Holding Trade Value Shares
Change
Change in
Stake
SAM
251
Smartleaf Asset Management
Massachusetts
$151K
Canada Pension Plan Investment Board
252
Canada Pension Plan Investment Board
Ontario, Canada
$148K
GFM
253
GF Fund Management
China
$140K
A
254
AlphaQuest
New York
$139K
ECSS
255
Eurizon Capital SGR SpA
$137K
HI
256
Horizon Investments
North Carolina
$102K
WSFS
257
Wilmington Savings Fund Society
Delaware
$96.9K
HFS
258
Hantz Financial Services
Michigan
$91K
US Bancorp
259
US Bancorp
Minnesota
$77.2K
Simplex Trading
260
Simplex Trading
Illinois
$72.2K
Jones Financial Companies
261
Jones Financial Companies
Missouri
$71.5K
MCM
262
MAI Capital Management
Ohio
$70K
IA
263
IFP Advisors
Florida
$65.3K
BNP Paribas Asset Management
264
BNP Paribas Asset Management
France
$65K
CT
265
Caldwell Trust
Florida
$61.6K
SS
266
SBI Securities
Japan
$49.8K
DB
267
Danske Bank
Denmark
$49.3K
HNB
268
Huntington National Bank
Ohio
$46.3K
SL
269
Salomon & Ludwin
Virginia
$44.8K
AF
270
Advisornet Financial
Minnesota
$42.2K
VC
271
Vestor Capital
Illinois
$42K
SCM
272
Sterling Capital Management
North Carolina
$39.9K
GRP
273
Global Retirement Partners
California
$39.4K
SIS
274
Sound Income Strategies
Florida
$39K
QCG
275
Quadrant Capital Group
Ohio
$38.5K