Krystal Biotech
      
      
        
          KRYS
        
        
      
    
  
          KRYS
        
        
      299 hedge funds and large institutions have $4.93B invested in Krystal Biotech in 2025 Q1 according to their latest regulatory filings, with 65 funds opening new positions, 87 increasing their positions, 112 reducing their positions, and 28 closing their positions.
New
  Increased
  Maintained
  Reduced
  Closed
  more call options, than puts
Call options by funds: $ | Put options by funds: $
more first-time investments, than exits
New positions opened: | Existing positions closed:
more funds holding in top 10
Funds holding in top 10: →
more capital invested
Capital invested by funds: $ → $
13% more funds holding
Funds holding: 264 → 299 (+35)
1.66% less ownership
Funds ownership: 96.57% → 94.91% (-1.7%)
22% less repeat investments, than reductions
Existing positions increased: 87 | Existing positions reduced: 112
    
      Holders
    
  
  
    
      
        
      
        299
      
    
      
    
  
    
      Holding in Top 10
    
  
  
    
      
        
      
        7
      
    
      
    
  
    
      Calls
    
  
  
    
      
        
      
        $54.2M
      
    
      
    
  
    
      Puts
    
  
  
    
      
        
      
        $17.6M
      
    
      
    
  
Top Buyers
| 1 | +$65.9M | |
| 2 | +$36.1M | |
| 3 | +$33.5M | |
| 4 |   
      1832 Asset Management
     
      
        Toronto,
      
      
        Ontario, Canada
      
     | +$24.5M | 
| 5 | 
    ACA
   
      Avoro Capital Advisors
     
      
      
        New York
      
     | +$18.4M | 
Top Sellers
| 1 | -$48.7M | |
| 2 | -$29.8M | |
| 3 | -$26.6M | |
| 4 | 
    DCM
   
      Driehaus Capital Management
     
      
        Chicago,
      
      
        Illinois
      
     | -$19.1M | 
| 5 | 
    FLSM
   
      Frazier Life Sciences Management
     
      
        Palo Alto,
      
      
        California
      
     | -$18M |