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Ionis Pharmaceuticals

Name Holding Trade Value Shares
Change
Change in
Stake
Charles Schwab
26
Charles Schwab
California
$47.3M +$2.43M +37,679 +7%
D.E. Shaw & Co
27
D.E. Shaw & Co
New York
$45.2M +$9.45M +146,492 +36%
Bank of New York Mellon
28
Bank of New York Mellon
New York
$42.1M -$724K -11,225 -2%
Goldman Sachs
29
Goldman Sachs
New York
$39.9M -$44.8M -693,876 -59%
Stifel Financial
30
Stifel Financial
Missouri
$38.2M -$7.42M -115,001 -20%
TAM
31
Tocqueville Asset Management
New York
$36.6M -$5.55M -86,029 -16%
Franklin Resources
32
Franklin Resources
California
$33.9M +$17.3M +268,820 +180%
SA
33
Sicart Associates
New York
$33.8M -$6.77M -104,974 -20%
AQR Capital Management
34
AQR Capital Management
Connecticut
$33M +$25.9M +402,227 +4,169%
CS
35
Candriam SCA
Luxembourg
$31.9M +$9.29M +144,000 +58%
Canada Pension Plan Investment Board
36
Canada Pension Plan Investment Board
Ontario, Canada
$31.5M -$1.56M -24,245 -6%
Morgan Stanley
37
Morgan Stanley
New York
$31.4M -$15.7M -243,006 -39%
Mitsubishi UFJ Trust & Banking
38
Mitsubishi UFJ Trust & Banking
Japan
$30M -$119K -1,840 -0.5%
CS
39
Credit Suisse
Switzerland
$28.4M -$10.2M -157,559 -31%
PP
40
PDT Partners
New York
$27.7M -$3.19M -49,500 -13%
Axa
41
Axa
France
$24.7M -$6.88M -106,688 -26%
Dimensional Fund Advisors
42
Dimensional Fund Advisors
Texas
$24.7M +$755K +11,709 +4%
BG
43
Bellevue Group
Switzerland
$24.6M -$5.16M -79,945 -21%
SI
44
Scout Investments
Missouri
$24.2M -$4.79M -74,214 -20%
New York State Common Retirement Fund
45
New York State Common Retirement Fund
New York
$24.2M +$3.34M +51,775 +21%
RCAMU
46
Rothschild & Co Asset Management US
Connecticut
$23.3M +$850K +13,184 +5%
Federated Hermes
47
Federated Hermes
Pennsylvania
$21.7M +$8.59M +133,178 +99%
Swiss National Bank
48
Swiss National Bank
Switzerland
$19.3M +$484K +7,500 +3%
AGA
49
Altrinsic Global Advisors
Connecticut
$19.3M -$18.7M -290,614 -55%
SGA
50
Sector Gamma AS
Norway
$19M -$9.4M -145,707 -38%