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Ionis Pharmaceuticals

Name Holding Trade Value Shares
Change
Change in
Stake
Two Sigma Advisers
26
Two Sigma Advisers
New York
$32.8M +$15.2M +298,700 +97%
FLAM
27
First Light Asset Management
Minnesota
$31.9M +$4.99M +97,870 +20%
Stifel Financial
28
Stifel Financial
Missouri
$31.7M -$1.03M -20,127 -3%
Charles Schwab
29
Charles Schwab
California
$29.5M +$973K +19,082 +4%
TAM
30
Tocqueville Asset Management
New York
$29M -$2.59M -50,839 -9%
MFWM
31
Motley Fool Wealth Management
Virginia
$28.9M -$80.7K -1,583 -0.3%
Bank of New York Mellon
32
Bank of New York Mellon
New York
$28.7M +$121K +2,380 +0.5%
AGA
33
Altrinsic Global Advisors
Connecticut
$28.6M +$206K +4,041 +0.8%
SA
34
Sicart Associates
New York
$28.2M -$96.1K -1,885 -0.4%
CS
35
Credit Suisse
Switzerland
$27.4M -$2.53M -49,618 -9%
Canada Pension Plan Investment Board
36
Canada Pension Plan Investment Board
Ontario, Canada
$22.3M +$1.06M +20,700 +5%
Axa
37
Axa
France
$22.2M +$2.38M +46,655 +13%
D.E. Shaw & Co
38
D.E. Shaw & Co
New York
$22.2M +$15M +294,184 +252%
PP
39
PDT Partners
New York
$21.2M -$1.89K -37 -0%
BG
40
Bellevue Group
Switzerland
$20.7M +$3.67M +72,052 +23%
SGA
41
Sector Gamma AS
Norway
$20.5M +$9.03M +176,987 +87%
SI
42
Scout Investments
Missouri
$20.1M +$104K +2,044 +0.6%
Mitsubishi UFJ Trust & Banking
43
Mitsubishi UFJ Trust & Banking
Japan
$20.1M -$377K -7,400 -2%
Dimensional Fund Advisors
44
Dimensional Fund Advisors
Texas
$15.8M +$1.23M +24,169 +9%
RCAMU
45
Rothschild & Co Asset Management US
Connecticut
$14.8M -$93.3K -1,829 -0.7%
PCM
46
Peregrine Capital Management
Minnesota
$14.5M -$96.4K -1,890 -0.7%
CTA
47
Carillon Tower Advisers
Florida
$13.8M +$309K +6,050 +2%
CS
48
Candriam SCA
Luxembourg
$13.5M +$2.5M +49,000 +24%
BBA
49
BLB&B Advisors
Pennsylvania
$13.4M -$122K -2,390 -1%
New York State Common Retirement Fund
50
New York State Common Retirement Fund
New York
$13.3M -$2.49M -48,813 -17%