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Ionis Pharmaceuticals

339 hedge funds and large institutions have $5.01B invested in Ionis Pharmaceuticals in 2025 Q1 according to their latest regulatory filings, with 54 funds opening new positions, 102 increasing their positions, 122 reducing their positions, and 61 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
339
Holders Change
-12
Holders Change %
-3.42%
% of All Funds
4.6%
Holding in Top 10
6
Holding in Top 10 Change
+2
Holding in Top 10 Change %
+50%
% of All Funds
0.08%
New
54
Increased
102
Reduced
122
Closed
61
Calls
$24.8M
Puts
$18.8M
Net Calls
+$6M
Net Calls Change
+$10.5M
Name Holding Trade Value Shares
Change
Shares
Change %
VPIM
201
Vanguard Personalized Indexing Management
California
$311K -$59.1K -1,958 -16%
TCM
202
Teza Capital Management
Illinois
$309K +$51.9K +1,719 +20%
Man Group
203
Man Group
United Kingdom
$303K +$51.8K +1,718 +21%
CC
204
Cypress Capital
Tennessee
$302K
Fifth Third Bancorp
205
Fifth Third Bancorp
Ohio
$301K +$13.8K +458 +5%
TRCT
206
Tower Research Capital (TRC)
New York
$298K -$130K -4,284 -30%
Focus Partners Wealth
207
Focus Partners Wealth
Massachusetts
$297K +$53.6K +1,777 +22%
VIA
208
Virtus Investment Advisers
Connecticut
$293K +$293K +9,701 New
SAM
209
Sectoral Asset Management
Quebec, Canada
$285K +$67.6K +2,240 +31%
Walleye Trading
210
Walleye Trading
New York
$282K -$16.9K -559 -6%
MIM
211
MetLife Investment Management
New Jersey
$276K -$483 -16 -0.2%
Marshall Wace
212
Marshall Wace
United Kingdom
$275K -$24.2M -803,204 -99%
JG
213
Jain Global
New York
$259K +$259K +8,595 New
QCM
214
Quantinno Capital Management
New York
$257K +$257K +8,515 New
BCM
215
Bayesian Capital Management
New York
$256K +$256K +8,500 New
Mirae Asset Global ETFs Holdings
216
Mirae Asset Global ETFs Holdings
Hong Kong
$256K -$38.8K -1,244 -13%
URS
217
Utah Retirement Systems
Utah
$253K
MSRPS
218
Maryland State Retirement & Pension System
Maryland
$250K
IAIM
219
International Assets Investment Management
Florida
$248K
IEFM
220
IQ EQ Fund Management
Ireland
$243K +$243K +8,059 New
FT
221
Fiduciary Trust
Massachusetts
$233K +$233K +7,738 New
SCM
222
Semanteon Capital Management
Massachusetts
$228K +$228K +7,543 New
CB
223
Commerce Bank
Missouri
$219K -$190K -6,309 -46%
ProShare Advisors
224
ProShare Advisors
Maryland
$216K -$9.32K -309 -4%
CA
225
Clearstead Advisors
Ohio
$211K -$5.58K -185 -3%