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Ionis Pharmaceuticals

339 hedge funds and large institutions have $5.01B invested in Ionis Pharmaceuticals in 2025 Q1 according to their latest regulatory filings, with 54 funds opening new positions, 102 increasing their positions, 122 reducing their positions, and 61 closing their positions.

New
Increased
Maintained
Reduced
Closed

more funds holding in top 10

Funds holding in top 10:

more call options, than puts

Call options by funds: $ | Put options by funds: $

more ownership

Funds ownership:

less funds holding

Funds holding:

11% less capital invested

Capital invested by funds: $5.61B → $5.01B (-$606M)

11% less first-time investments, than exits

New positions opened: 54 | Existing positions closed: 61

16% less repeat investments, than reductions

Existing positions increased: 102 | Existing positions reduced: 122

Holders
339
Holders Change
Holders Change %
% of All Funds
Holding in Top 10
6
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
Increased
Reduced
Closed
Calls
$24.8M
Puts
$18.8M
Net Calls
Net Calls Change

Top Buyers

1 +$79.4M
2 +$60.5M
3 +$57.7M
4
Citadel Advisors
Citadel Advisors
Florida
+$39.6M
5
Fidelity Investments
Fidelity Investments
Massachusetts
+$27.9M
Name Holding Trade Value Shares
Change
Change in
Stake
VPIM
201
Vanguard Personalized Indexing Management
California
$311K
TCM
202
Teza Capital Management
Illinois
$309K
Man Group
203
Man Group
United Kingdom
$303K
CC
204
Cypress Capital
Tennessee
$302K
Fifth Third Bancorp
205
Fifth Third Bancorp
Ohio
$301K
TRCT
206
Tower Research Capital (TRC)
New York
$298K
Focus Partners Wealth
207
Focus Partners Wealth
Massachusetts
$297K
VIA
208
Virtus Investment Advisers
Connecticut
$293K
SAM
209
Sectoral Asset Management
Quebec, Canada
$285K
Walleye Trading
210
Walleye Trading
New York
$282K
MIM
211
MetLife Investment Management
New Jersey
$276K
Marshall Wace
212
Marshall Wace
United Kingdom
$275K
JG
213
Jain Global
New York
$259K
QCM
214
Quantinno Capital Management
New York
$257K
BCM
215
Bayesian Capital Management
New York
$256K
Mirae Asset Global ETFs Holdings
216
Mirae Asset Global ETFs Holdings
Hong Kong
$256K
URS
217
Utah Retirement Systems
Utah
$253K
MSRPS
218
Maryland State Retirement & Pension System
Maryland
$250K
IAIM
219
International Assets Investment Management
Florida
$248K
IEFM
220
IQ EQ Fund Management
Ireland
$243K
FT
221
Fiduciary Trust
Massachusetts
$233K
SCM
222
Semanteon Capital Management
Massachusetts
$228K
CB
223
Commerce Bank
Missouri
$219K
ProShare Advisors
224
ProShare Advisors
Maryland
$216K
CA
225
Clearstead Advisors
Ohio
$211K