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441 hedge funds and large institutions have $15.3B invested in Insmed in 2025 Q1 according to their latest regulatory filings, with 56 funds opening new positions, 185 increasing their positions, 151 reducing their positions, and 48 closing their positions.

New
Increased
Maintained
Reduced
Closed

23% more repeat investments, than reductions

Existing positions increased: 185 | Existing positions reduced: 151

17% more first-time investments, than exits

New positions opened: 56 | Existing positions closed: 48

15% more capital invested

Capital invested by funds: $13.3B → $15.3B (+$2.01B)

7% more funds holding in top 10

Funds holding in top 10: 2931 (+2)

2.65% more ownership

Funds ownership: 107.64%110.29% (+2.7%)

1% more funds holding

Funds holding: 438441 (+3)

50% less call options, than puts

Call options by funds: $73M | Put options by funds: $145M

Holders
441
Holders Change
+3
Holders Change %
+0.68%
% of All Funds
5.91%
Holding in Top 10
31
Holding in Top 10 Change
+2
Holding in Top 10 Change %
+6.9%
% of All Funds
0.42%
New
56
Increased
185
Reduced
151
Closed
48
Calls
$73M
Puts
$145M
Net Calls
-$72M
Net Calls Change
-$110M
Name Holding Trade Value Shares
Change
Change in
Stake
Deutsche Bank
101
Deutsche Bank
Germany
$23.7M -$13.6M -178,348 -36%
SFM
102
Soros Fund Management
New York
$23.4M -$11.3M -147,878 -32%
PAM
103
Panagora Asset Management
Massachusetts
$23.4M -$799K -10,445 -3%
SI
104
Sofinnova Investments
California
$23.2M +$3.67M +47,973 +19%
RhumbLine Advisers
105
RhumbLine Advisers
Massachusetts
$23.2M +$1.16M +15,220 +5%
Russell Investments Group
106
Russell Investments Group
United Kingdom
$23.1M +$13.1M +170,842 +129%
Comerica Bank
107
Comerica Bank
Texas
$22.1M +$9.14M +119,495 +70%
Barclays
108
Barclays
United Kingdom
$21.3M -$5.75M -75,166 -21%
Citigroup
109
Citigroup
New York
$21.2M +$2.3M +30,106 +12%
SCM
110
Soleus Capital Management
Connecticut
$20.9M -$3.52M -46,000 -14%
California Public Employees Retirement System
111
California Public Employees Retirement System
California
$20.3M +$698K +9,122 +4%
BGI
112
B Group Inc
Texas
$20M -$6.69M -87,500 -25%
DTC
113
Deep Track Capital
Connecticut
$19.4M +$19.5M +254,751 New
WP
114
Woodline Partners
California
$19M +$6.62M +86,540 +53%
Royal Bank of Canada
115
Royal Bank of Canada
Ontario, Canada
$18.7M +$4.68M +61,190 +33%
NIP
116
Nicholas Investment Partners
California
$17.1M +$3.15M +41,188 +23%
KCM
117
Kingdon Capital Management
New York
$16.4M -$765K -10,000 -4%
Wells Fargo
118
Wells Fargo
California
$15.7M +$3.43M +44,802 +28%
Axa
119
Axa
France
$15.6M -$1.76M -22,964 -10%
RCM
120
RA Capital Management
Massachusetts
$15.3M
Federated Hermes
121
Federated Hermes
Pennsylvania
$14.7M -$3.3M -43,193 -18%
GIM
122
Granahan Investment Management
Massachusetts
$14.3M -$1.65M -21,552 -10%
CCM
123
Cutter Capital Management
New York
$14.2M -$1.87M -24,500 -12%
RPAM
124
Rhenman & Partners Asset Management
Sweden
$14.2M +$9.49M +124,000 +202%
PCM
125
Peregrine Capital Management
Minnesota
$13.8M -$955K -12,486 -6%

INSM Hedge Fund Activity: Q1 2025 in Review

441 of the 7,458 institutional investors tracked by Wall St. Rank reported a position in Insmed (INSM) for Q1 2025, worth a combined $15.3B — up 15% from $13.3B a quarter earlier.

Buyers outnumbered sellers: 56 funds opened new INSM positions and 48 closed out — a net gain of 8 holders — while 185 added to existing stakes and 151 trimmed.

The largest buyer was JP Morgan Chase, adding an estimated $235M. The largest seller was Fidelity Investments, cutting an estimated $112M.

  • 441 institutional investors held Insmed (INSM) as of Q1 2025, up from 438 in Q4 2024.
  • Funds reported $15.3B of Insmed stock for Q1 2025, up 15% quarter-over-quarter.
  • 56 funds opened new Insmed positions in Q1 2025 and 48 closed out, a net change of +8 holders.
  • The largest Insmed buyer in Q1 2025 was JP Morgan Chase, an estimated $235M added.
  • The largest Insmed seller in Q1 2025 was Fidelity Investments, an estimated $112M sold.

Based on aggregated 13F filings for Q1 2025.