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441 hedge funds and large institutions have $15.3B invested in Insmed in 2025 Q1 according to their latest regulatory filings, with 56 funds opening new positions, 185 increasing their positions, 151 reducing their positions, and 48 closing their positions.

New
Increased
Maintained
Reduced
Closed

23% more repeat investments, than reductions

Existing positions increased: 185 | Existing positions reduced: 151

17% more first-time investments, than exits

New positions opened: 56 | Existing positions closed: 48

15% more capital invested

Capital invested by funds: $13.3B → $15.3B (+$2.01B)

7% more funds holding in top 10

Funds holding in top 10: 2931 (+2)

2.65% more ownership

Funds ownership: 107.64%110.29% (+2.7%)

1% more funds holding

Funds holding: 438441 (+3)

50% less call options, than puts

Call options by funds: $73M | Put options by funds: $145M

Holders
441
Holders Change
+3
Holders Change %
+0.68%
% of All Funds
5.91%
Holding in Top 10
31
Holding in Top 10 Change
+2
Holding in Top 10 Change %
+6.9%
% of All Funds
0.42%
New
56
Increased
185
Reduced
151
Closed
48
Calls
$73M
Puts
$145M
Net Calls
-$72M
Net Calls Change
-$110M
Name Holding Trade Value Shares
Change
Change in
Stake
SIG
451
Senator Investment Group
New York
-$8.28M -120,000 Closed
JGC
452
J. Goldman & Co
New York
-$7.97M -104,179 Closed
HT
453
HAP Trading
New York
-$6.04M -87,533 Closed
Twin Tree Management
454
Twin Tree Management
Texas
-$4.5M -65,147 Closed
Balyasny Asset Management
455
Balyasny Asset Management
Illinois
-$4.07M -58,970 Closed
DP
456
Diadema Partners
New Jersey
-$3.89M -56,337 Closed
PHS
457
PFM Health Sciences
California
-$3.02M -43,774 Closed
EP
458
Edgestream Partners
New Jersey
-$3.01M -43,619 Closed
Treasurer of the State of North Carolina
459
Treasurer of the State of North Carolina
North Carolina
-$2.88M -41,770 Closed
LIP
460
Lighthouse Investment Partners
Florida
-$2.98M -39,000 Closed
SCM
461
Superstring Capital Management
New York
-$2.48M -35,966 Closed
Man Group
462
Man Group
United Kingdom
-$2M -28,963 Closed
Renaissance Technologies
463
Renaissance Technologies
New York
-$1.75M -25,287 Closed
Baird Financial Group
464
Baird Financial Group
Wisconsin
-$1.54M -22,289 Closed
MASUI
465
MIRAE ASSET SECURITIES (USA) INC.
New York
-$962K -13,936 Closed
PAMP
466
Polar Asset Management Partners
Ontario, Canada
-$904K -13,100 Closed
PAP
467
Persistent Asset Partners
Hong Kong
-$957K -12,500 Closed
AIM
468
Aigen Investment Management
New York
-$824K -11,936 Closed
CFM
469
Catalyst Funds Management
Australia
-$777K -11,250 Closed
CCG
470
Capital CS Group
California
-$586K -8,488 Closed
FGP
471
Freestone Grove Partners
California
-$524K -7,583 Closed
SI
472
Saxon Interests
Texas
-$425K -6,163 Closed
OGC
473
One68 Global Capital
New York
-$345K -5,000 Closed
VEA
474
Virtus ETF Advisers
New York
-$335K -4,853 Closed
T
475
TOBAM
France
-$321K -4,643 Closed

INSM Hedge Fund Activity: Q1 2025 in Review

441 of the 7,458 institutional investors tracked by Wall St. Rank reported a position in Insmed (INSM) for Q1 2025, worth a combined $15.3B — up 15% from $13.3B a quarter earlier.

Buyers outnumbered sellers: 56 funds opened new INSM positions and 48 closed out — a net gain of 8 holders — while 185 added to existing stakes and 151 trimmed.

The largest buyer was JP Morgan Chase, adding an estimated $235M. The largest seller was Fidelity Investments, cutting an estimated $112M.

  • 441 institutional investors held Insmed (INSM) as of Q1 2025, up from 438 in Q4 2024.
  • Funds reported $15.3B of Insmed stock for Q1 2025, up 15% quarter-over-quarter.
  • 56 funds opened new Insmed positions in Q1 2025 and 48 closed out, a net change of +8 holders.
  • The largest Insmed buyer in Q1 2025 was JP Morgan Chase, an estimated $235M added.
  • The largest Insmed seller in Q1 2025 was Fidelity Investments, an estimated $112M sold.

Based on aggregated 13F filings for Q1 2025.