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441 hedge funds and large institutions have $15.3B invested in Insmed in 2025 Q1 according to their latest regulatory filings, with 56 funds opening new positions, 185 increasing their positions, 151 reducing their positions, and 48 closing their positions.

New
Increased
Maintained
Reduced
Closed

23% more repeat investments, than reductions

Existing positions increased: 185 | Existing positions reduced: 151

17% more first-time investments, than exits

New positions opened: 56 | Existing positions closed: 48

15% more capital invested

Capital invested by funds: $13.3B → $15.3B (+$2.01B)

7% more funds holding in top 10

Funds holding in top 10: 2931 (+2)

2.65% more ownership

Funds ownership: 107.64%110.29% (+2.7%)

1% more funds holding

Funds holding: 438441 (+3)

50% less call options, than puts

Call options by funds: $73M | Put options by funds: $145M

Holders
441
Holders Change
+3
Holders Change %
+0.68%
% of All Funds
5.91%
Holding in Top 10
31
Holding in Top 10 Change
+2
Holding in Top 10 Change %
+6.9%
% of All Funds
0.42%
New
56
Increased
185
Reduced
151
Closed
48
Calls
$73M
Puts
$145M
Net Calls
-$72M
Net Calls Change
-$110M
Name Holding Trade Value Shares
Change
Change in
Stake
GAM
251
Groupama Asset Management
France
$970K
Corient Private Wealth
252
Corient Private Wealth
Florida
$940K -$184K -2,411 -16%
Los Angeles Capital Management
253
Los Angeles Capital Management
California
$922K +$220K +2,879 +31%
GT
254
Glenmede Trust
Pennsylvania
$881K +$520K +6,799 +143%
SP
255
SIH Partners
Delaware
$871K +$873K +11,415 New
US Bancorp
256
US Bancorp
Minnesota
$864K +$137K +1,790 +19%
PAS
257
Park Avenue Securities
New York
$842K +$236K +3,081 +39%
PNC Financial Services Group
258
PNC Financial Services Group
Pennsylvania
$812K +$134K +1,756 +20%
BMSSC
259
B. Metzler seel. Sohn & Co
Germany
$802K
SAM
260
Shell Asset Management
Netherlands
$773K -$32.2K -421 -4%
AI
261
Allostery Investments
Connecticut
$763K
ACM
262
Aster Capital Management
United Arab Emirates
$756K +$708K +9,251 +46,255%
OSAM
263
O'Shaughnessy Asset Management
Connecticut
$750K +$88.4K +1,155 +13%
AI
264
Atria Investments
North Carolina
$732K +$333K +4,359 +83%
AAS
265
Avantax Advisory Services
Texas
$725K +$40.5K +530 +6%
NIM
266
NEOS Investment Management
Connecticut
$700K -$111K -1,445 -14%
TE
267
Tema ETFs
New York
$700K -$111K -1,445 -14%
WPW
268
Waldron Private Wealth
Pennsylvania
$671K
BFA
269
Beacon Financial Advisory
Ohio
$663K -$18.7K -245 -3%
KeyBank National Association
270
KeyBank National Association
Ohio
$632K -$38.3K -501 -6%
VPIM
271
Vanguard Personalized Indexing Management
California
$625K +$130K +1,694 +26%
MA
272
MYDA Advisors
New York
$610K +$612K +8,000 New
KBC Group
273
KBC Group
Belgium
$576K +$51.9K +678 +10%
QC
274
Quadrature Capital
United Kingdom
$571K +$573K +7,486 New
TRCT
275
Tower Research Capital (TRC)
New York
$566K -$847K -11,072 -60%

INSM Hedge Fund Activity: Q1 2025 in Review

441 of the 7,458 institutional investors tracked by Wall St. Rank reported a position in Insmed (INSM) for Q1 2025, worth a combined $15.3B — up 15% from $13.3B a quarter earlier.

Buyers outnumbered sellers: 56 funds opened new INSM positions and 48 closed out — a net gain of 8 holders — while 185 added to existing stakes and 151 trimmed.

The largest buyer was JP Morgan Chase, adding an estimated $235M. The largest seller was Fidelity Investments, cutting an estimated $112M.

  • 441 institutional investors held Insmed (INSM) as of Q1 2025, up from 438 in Q4 2024.
  • Funds reported $15.3B of Insmed stock for Q1 2025, up 15% quarter-over-quarter.
  • 56 funds opened new Insmed positions in Q1 2025 and 48 closed out, a net change of +8 holders.
  • The largest Insmed buyer in Q1 2025 was JP Morgan Chase, an estimated $235M added.
  • The largest Insmed seller in Q1 2025 was Fidelity Investments, an estimated $112M sold.

Based on aggregated 13F filings for Q1 2025.