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441 hedge funds and large institutions have $15.3B invested in Insmed in 2025 Q1 according to their latest regulatory filings, with 56 funds opening new positions, 185 increasing their positions, 151 reducing their positions, and 48 closing their positions.

New
Increased
Maintained
Reduced
Closed

23% more repeat investments, than reductions

Existing positions increased: 185 | Existing positions reduced: 151

17% more first-time investments, than exits

New positions opened: 56 | Existing positions closed: 48

15% more capital invested

Capital invested by funds: $13.3B → $15.3B (+$2.01B)

7% more funds holding in top 10

Funds holding in top 10: 2931 (+2)

2.65% more ownership

Funds ownership: 107.64%110.29% (+2.7%)

1% more funds holding

Funds holding: 438441 (+3)

50% less call options, than puts

Call options by funds: $73M | Put options by funds: $145M

Holders
441
Holders Change
+3
Holders Change %
+0.68%
% of All Funds
5.91%
Holding in Top 10
31
Holding in Top 10 Change
+2
Holding in Top 10 Change %
+6.9%
% of All Funds
0.42%
New
56
Increased
185
Reduced
151
Closed
48
Calls
$73M
Puts
$145M
Net Calls
-$72M
Net Calls Change
-$110M
Name Holding Trade Value Shares
Change
Change in
Stake
BFM
226
Boothbay Fund Management
New York
$1.86M -$718K -9,390 -28%
CCM
227
Cinctive Capital Management
New York
$1.8M -$130K -1,699 -7%
HS
228
HighVista Strategies
Massachusetts
$1.64M -$472K -6,172 -22%
XT
229
XTX Topco
Cayman Islands
$1.62M +$1.63M +21,250 New
HSBC Holdings
230
HSBC Holdings
United Kingdom
$1.61M +$24.1K +315 +1%
Cetera Investment Advisers
231
Cetera Investment Advisers
Illinois
$1.58M +$805K +10,525 +104%
SAM
232
Simplify Asset Management
Nevada
$1.57M +$8.41K +110 +0.5%
OAM
233
Oppenheimer Asset Management
New York
$1.52M +$417K +5,453 +38%
Public Employees Retirement Association of Colorado
234
Public Employees Retirement Association of Colorado
Colorado
$1.49M
SFAM
235
Springhill Fund Asset Management
Hong Kong
$1.46M -$3.85M -50,308 -72%
NYLIM
236
New York Life Investment Management
New York
$1.43M +$71.1K +929 +5%
DIA
237
Dana Investment Advisors
Wisconsin
$1.41M -$210K -2,747 -13%
SC
238
SummitTX Capital
Texas
$1.37M +$1.37M +17,928 New
AIP
239
Ameritas Investment Partners
Nebraska
$1.34M
SSA
240
Schonfeld Strategic Advisors
New York
$1.24M +$609K +7,961 +96%
VRS
241
Virginia Retirement Systems
Virginia
$1.23M +$1.23M +16,065 New
CP
242
CenterBook Partners
Connecticut
$1.22M +$505K +6,600 +70%
SAM
243
Sectoral Asset Management
Quebec, Canada
$1.16M +$601K +7,859 +107%
Connor, Clark & Lunn Investment Management (CC&L)
244
Connor, Clark & Lunn Investment Management (CC&L)
British Columbia, Canada
$1.16M +$1.16M +15,143 New
Simplex Trading
245
Simplex Trading
Illinois
$1.1M -$325K -4,248 -23%
HC
246
Henshaw Capital
Massachusetts
$1.1M
EFM
247
E Fund Management
China
$1.04M +$60K +785 +6%
X
248
Xponance
Pennsylvania
$1.02M +$51.3K +670 +5%
Mackenzie Financial
249
Mackenzie Financial
Ontario, Canada
$1,000K +$170K +2,220 +20%
TRSOTSOK
250
Teachers Retirement System of the State of Kentucky
Kentucky
$975K +$977K +12,775 New

INSM Hedge Fund Activity: Q1 2025 in Review

441 of the 7,458 institutional investors tracked by Wall St. Rank reported a position in Insmed (INSM) for Q1 2025, worth a combined $15.3B — up 15% from $13.3B a quarter earlier.

Buyers outnumbered sellers: 56 funds opened new INSM positions and 48 closed out — a net gain of 8 holders — while 185 added to existing stakes and 151 trimmed.

The largest buyer was JP Morgan Chase, adding an estimated $235M. The largest seller was Fidelity Investments, cutting an estimated $112M.

  • 441 institutional investors held Insmed (INSM) as of Q1 2025, up from 438 in Q4 2024.
  • Funds reported $15.3B of Insmed stock for Q1 2025, up 15% quarter-over-quarter.
  • 56 funds opened new Insmed positions in Q1 2025 and 48 closed out, a net change of +8 holders.
  • The largest Insmed buyer in Q1 2025 was JP Morgan Chase, an estimated $235M added.
  • The largest Insmed seller in Q1 2025 was Fidelity Investments, an estimated $112M sold.

Based on aggregated 13F filings for Q1 2025.