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Immunome

142 hedge funds and large institutions have $739M invested in Immunome in 2025 Q2 according to their latest regulatory filings, with 27 funds opening new positions, 55 increasing their positions, 38 reducing their positions, and 26 closing their positions.

New
Increased
Maintained
Reduced
Closed

45% more repeat investments, than reductions

Existing positions increased: 55 | Existing positions reduced: 38

42% more capital invested

Capital invested by funds: $518M → $739M (+$220M)

2.8% more ownership

Funds ownership: 88.49%91.29% (+2.8%)

4% more first-time investments, than exits

New positions opened: 27 | Existing positions closed: 26

0% more funds holding

Funds holding: 142142 (0)

0% more funds holding in top 10

Funds holding in top 10: 33 (0)

97% less call options, than puts

Call options by funds: $1.07M | Put options by funds: $39.5M

Holders
142
Holders Change
Holders Change %
0%
% of All Funds
1.87%
Holding in Top 10
3
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
0.04%
New
27
Increased
55
Reduced
38
Closed
26
Calls
$1.07M
Puts
$39.5M
Net Calls
-$38.5M
Net Calls Change
-$9.84M
Name Holding Trade Value Shares
Change
Change in
Stake
MIM
76
MetLife Investment Management
New Jersey
$394K
Los Angeles Capital Management
77
Los Angeles Capital Management
California
$389K +$49.3K +6,009 +17%
Wells Fargo
78
Wells Fargo
California
$388K +$46.4K +5,661 +16%
IIM
79
INTECH Investment Management
Florida
$377K +$50.3K +6,141 +18%
California State Teachers Retirement System (CalSTRS)
80
California State Teachers Retirement System (CalSTRS)
California
$356K +$7.15K +872 +2%
TBWA
81
Three Bridge Wealth Advisors
California
$350K
Invesco
82
Invesco
Georgia
$268K +$3.39K +413 +1%
DS
83
DRW Securities
Illinois
$261K +$230K +28,099 New
Simplex Trading
84
Simplex Trading
Illinois
$256K +$127K +15,445 +127%
Two Sigma Investments
85
Two Sigma Investments
New York
$248K -$517K -63,070 -70%
BIM
86
Baldwin Investment Management
Pennsylvania
$236K
Zurich Cantonal Bank
87
Zurich Cantonal Bank
Switzerland
$197K +$108K +13,143 +164%
CF
88
Cantor Fitzgerald
New York
$195K +$172K +21,000 New
Commonwealth Equity Services
89
Commonwealth Equity Services
Massachusetts
$195K +$3.05K +372 +2%
Man Group
90
Man Group
United Kingdom
$192K -$15.8K -1,931 -9%
ASRS
91
Arizona State Retirement System
Arizona
$188K +$12.3K +1,502 +8%
VOYA Investment Management
92
VOYA Investment Management
Georgia
$188K +$10.7K +1,308 +7%
CFG
93
Citizens Financial Group
Rhode Island
$186K
SFA
94
Sequoia Financial Advisors
Ohio
$177K
Teacher Retirement System of Texas
95
Teacher Retirement System of Texas
Texas
$172K +$9.74K +1,188 +7%
Creative Planning
96
Creative Planning
Kansas
$167K +$147K +17,954 New
PA
97
Profund Advisors
Maryland
$154K -$41.5K -5,064 -23%
PFSRSONJ
98
Police & Firemen's Retirement System of New Jersey
New Jersey
$143K
ProShare Advisors
99
ProShare Advisors
Maryland
$140K -$1.98K -241 -2%
WWM
100
Whalen Wealth Management
Nevada
$128K +$113K +13,722 New

IMNM Hedge Fund Activity: Q2 2025 in Review

142 of the 7,595 institutional investors tracked by Wall St. Rank reported a position in Immunome (IMNM) for Q2 2025, worth a combined $739M — up 42% from $518M a quarter earlier.

Buyers outnumbered sellers: 27 funds opened new IMNM positions and 26 closed out — a net gain of 1 holder — while 55 added to existing stakes and 38 trimmed.

The largest buyer was Fidelity Investments, adding an estimated $18.7M. The largest seller was Susquehanna International Group, cutting an estimated $10.2M.

  • 142 institutional investors held Immunome (IMNM) as of Q2 2025, unchanged from Q1 2025.
  • Funds reported $739M of Immunome stock for Q2 2025, up 42% quarter-over-quarter.
  • 27 funds opened new Immunome positions in Q2 2025 and 26 closed out, a net change of +1 holder.
  • The largest Immunome buyer in Q2 2025 was Fidelity Investments, an estimated $18.7M added.
  • The largest Immunome seller in Q2 2025 was Susquehanna International Group, an estimated $10.2M sold.

Based on aggregated 13F filings for Q2 2025.