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Immunome

142 hedge funds and large institutions have $739M invested in Immunome in 2025 Q2 according to their latest regulatory filings, with 27 funds opening new positions, 55 increasing their positions, 38 reducing their positions, and 26 closing their positions.

New
Increased
Maintained
Reduced
Closed

45% more repeat investments, than reductions

Existing positions increased: 55 | Existing positions reduced: 38

42% more capital invested

Capital invested by funds: $518M → $739M (+$220M)

2.8% more ownership

Funds ownership: 88.49%91.29% (+2.8%)

4% more first-time investments, than exits

New positions opened: 27 | Existing positions closed: 26

0% more funds holding

Funds holding: 142142 (0)

0% more funds holding in top 10

Funds holding in top 10: 33 (0)

97% less call options, than puts

Call options by funds: $1.07M | Put options by funds: $39.5M

Holders
142
Holders Change
Holders Change %
0%
% of All Funds
1.87%
Holding in Top 10
3
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
0.04%
New
27
Increased
55
Reduced
38
Closed
26
Calls
$1.07M
Puts
$39.5M
Net Calls
-$38.5M
Net Calls Change
-$9.84M
Name Holding Trade Value Shares
Change
Change in
Stake
T. Rowe Price Investment Management
1
T. Rowe Price Investment Management
Maryland
$77M +$5.91M +720,663 +10%
Fidelity Investments
2
Fidelity Investments
Massachusetts
$57.4M +$18.7M +2,275,348 +58%
BlackRock
3
BlackRock
New York
$53.7M +$885K +107,993 +2%
RG
4
Redmile Group
California
$45.3M -$4.01M -488,962 -9%
ES
5
Enavate Sciences
California
$44.3M
Point72 Asset Management
6
Point72 Asset Management
Connecticut
$43.6M +$2.67M +325,128 +7%
Vanguard Group
7
Vanguard Group
Pennsylvania
$42.1M +$1.79M +217,761 +5%
EC
8
EcoR1 Capital
California
$37.9M
OM
9
Opaleye Management
Massachusetts
$32.8M -$167K -20,419 -0.6%
Primecap Management
10
Primecap Management
California
$28.1M -$3.23M -393,490 -12%
T. Rowe Price Associates
11
T. Rowe Price Associates
Maryland
$27.7M -$718K -87,527 -3%
State Street
12
State Street
Massachusetts
$23.4M -$980K -119,527 -5%
Toronto Dominion Bank
13
Toronto Dominion Bank
Ontario, Canada
$19.4M +$17.1M +2,085,700 New
JFG
14
Jefferies Financial Group
New York
$19.4M -$1.66M -202,340 -9%
Geode Capital Management
15
Geode Capital Management
Massachusetts
$17.3M +$964K +117,523 +7%
WP
16
Woodline Partners
California
$15.4M +$7.66K +934 +0.1%
RAM
17
Readystate Asset Management
Illinois
$12.6M +$9.26M +1,129,346 +504%
Marshall Wace
18
Marshall Wace
United Kingdom
$12.1M -$2.57M -312,956 -19%
Janus Henderson Group
19
Janus Henderson Group
United Kingdom
$9.68M -$8.59M -1,048,081 -50%
PCH
20
Polar Capital Holdings
United Kingdom
$9.3M +$8.2M +1,000,000 New
SI
21
Sofinnova Investments
California
$7.24M -$83.5K -10,190 -1%
Northern Trust
22
Northern Trust
Illinois
$6.43M -$56.1K -6,844 -1%
Charles Schwab
23
Charles Schwab
California
$5.95M +$212K +25,862 +4%
TD Asset Management
24
TD Asset Management
Ontario, Canada
$5.63M -$10.1K -1,232 -0.2%
JP Morgan Chase
25
JP Morgan Chase
New York
$5.36M -$356K -43,408 -7%

IMNM Hedge Fund Activity: Q2 2025 in Review

142 of the 7,595 institutional investors tracked by Wall St. Rank reported a position in Immunome (IMNM) for Q2 2025, worth a combined $739M — up 42% from $518M a quarter earlier.

Buyers outnumbered sellers: 27 funds opened new IMNM positions and 26 closed out — a net gain of 1 holder — while 55 added to existing stakes and 38 trimmed.

The largest buyer was Fidelity Investments, adding an estimated $18.7M. The largest seller was Susquehanna International Group, cutting an estimated $10.2M.

  • 142 institutional investors held Immunome (IMNM) as of Q2 2025, unchanged from Q1 2025.
  • Funds reported $739M of Immunome stock for Q2 2025, up 42% quarter-over-quarter.
  • 27 funds opened new Immunome positions in Q2 2025 and 26 closed out, a net change of +1 holder.
  • The largest Immunome buyer in Q2 2025 was Fidelity Investments, an estimated $18.7M added.
  • The largest Immunome seller in Q2 2025 was Susquehanna International Group, an estimated $10.2M sold.

Based on aggregated 13F filings for Q2 2025.