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Immunome
IMNM

142 hedge funds and large institutions have $518M invested in Immunome in 2025 Q1 according to their latest regulatory filings, with 39 funds opening new positions, 71 increasing their positions, 16 reducing their positions, and 17 closing their positions.

New
Increased
Maintained
Reduced
Closed

344% more repeat investments, than reductions

Existing positions increased: 71 | Existing positions reduced: 16

129% more first-time investments, than exits

New positions opened: 39 | Existing positions closed: 17

18% more funds holding

Funds holding: 120 → 142 (+22)

3.08% more ownership

Funds ownership: 85.41% → 88.49% (+3.1%)

0% more funds holding in top 10

Funds holding in top 10: 3 → 3 (0)

8% less capital invested

Capital invested by funds: $566M → $518M (-$47.9M)

98% less call options, than puts

Call options by funds: $449K | Put options by funds: $29.1M

Holders
142
Holders Change
+22
Holders Change %
+18.33%
% of All Funds
1.9%
Holding in Top 10
3
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
0.04%
New
39
Increased
71
Reduced
16
Closed
17
Calls
$449K
Puts
$29.1M
Net Calls
-$28.6M
Net Calls Change
-$7.17M

Top Buyers

1
Point72 Asset Management
Point72 Asset Management
Connecticut
+$35.2M
2
Primecap Management
Primecap Management
California
+$30.1M
3
T. Rowe Price Investment Management
T. Rowe Price Investment Management
Maryland
+$19.7M
4
BlackRock
BlackRock
New York
+$14.8M
5
OM
Opaleye Management
Massachusetts
+$14.5M

Top Sellers

1
Janus Henderson Group
Janus Henderson Group
United Kingdom
-$13.1M
2
Renaissance Technologies
Renaissance Technologies
New York
-$1.92M
3
Qube Research & Technologies (QRT)
Qube Research & Technologies (QRT)
United Kingdom
-$1.14M
4
CSS
Cubist Systematic Strategies
Connecticut
-$902K
5
Goldman Sachs
Goldman Sachs
New York
-$772K
Name Holding Trade Value Shares
Change 		Change in
Stake
T. Rowe Price Investment Management
1
T. Rowe Price Investment Management
Maryland
$50.8M +$19.7M +2,054,640 +37%
BlackRock
2
BlackRock
New York
$38.1M +$14.8M +1,537,711 +37%
RG
3
Redmile Group
California
$36.1M +$5.12M +533,161 +11%
ES
4
Enavate Sciences
California
$32.1M +$12.4M +1,290,322 +37%
Point72 Asset Management
5
Point72 Asset Management
Connecticut
$29.3M +$35.2M +3,671,885 +533%
Vanguard Group
6
Vanguard Group
Pennsylvania
$29M +$12.5M +1,303,753 +43%
EC
7
EcoR1 Capital
California
$27.5M +$1.92M +200,000 +5%
Fidelity Investments
8
Fidelity Investments
Massachusetts
$26.2M -$258K -26,898 -0.7%
OM
9
Opaleye Management
Massachusetts
$23.9M +$14.5M +1,510,000 +74%
Primecap Management
10
Primecap Management
California
$23M +$30.1M +3,132,900 +1,116%
T. Rowe Price Associates
11
T. Rowe Price Associates
Maryland
$20.7M +$7.55M +786,853 +34%
State Street
12
State Street
Massachusetts
$17.8M +$4.93M +513,608 +24%
JFG
13
Jefferies Financial Group
New York
$15.4M +$2.76M +288,000 +14%
Janus Henderson Group
14
Janus Henderson Group
United Kingdom
$14.6M -$13.1M -1,367,444 -40%
Geode Capital Management
15
Geode Capital Management
Massachusetts
$11.7M +$4.93M +514,206 +42%
WP
16
Woodline Partners
California
$11.2M +$6.49M +676,804 +69%
Marshall Wace
17
Marshall Wace
United Kingdom
$10.8M +$3.79M +394,526 +32%
Susquehanna International Group
18
Susquehanna International Group
Pennsylvania
$9.27M +$12.4M +1,294,458 +1,567%
Morgan Stanley
19
Morgan Stanley
New York
$5.82M +$4.46M +465,356 +117%
SI
20
Sofinnova Investments
California
$5.31M +$401K +41,842 +6%
Adage Capital Partners
21
Adage Capital Partners
Massachusetts
$5.22M +$2.64M +275,000 +55%
CM
22
Caption Management
Oklahoma
$5.05M +$7.2M +750,000 New
Northern Trust
23
Northern Trust
Illinois
$4.7M +$1.75M +181,910 +35%
JP Morgan Chase
24
JP Morgan Chase
New York
$4.17M -$279K -29,072 -4%
Charles Schwab
25
Charles Schwab
California
$4.13M +$1.51M +157,135 +34%
1
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IMNM Hedge Fund Activity: Q1 2025 in Review

142 of the 7,457 institutional investors tracked by Wall St. Rank reported a position in Immunome (IMNM) for Q1 2025, worth a combined $518M — down 8.5% from $566M a quarter earlier.

Buyers outnumbered sellers: 39 funds opened new IMNM positions and 17 closed out — a net gain of 22 holders — while 71 added to existing stakes and 16 trimmed.

The largest buyer was Point72 Asset Management, adding an estimated $35.2M. The largest seller was Janus Henderson Group, cutting an estimated $13.1M.

  • 142 institutional investors held Immunome (IMNM) as of Q1 2025, up from 120 in Q4 2024.
  • Funds reported $518M of Immunome stock for Q1 2025, down 8.5% quarter-over-quarter.
  • 39 funds opened new Immunome positions in Q1 2025 and 17 closed out, a net change of +22 holders.
  • The largest Immunome buyer in Q1 2025 was Point72 Asset Management, an estimated $35.2M added.
  • The largest Immunome seller in Q1 2025 was Janus Henderson Group, an estimated $13.1M sold.

Based on aggregated 13F filings for Q1 2025.