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Immunome

153 hedge funds and large institutions have $1.07B invested in Immunome in 2025 Q3 according to their latest regulatory filings, with 27 funds opening new positions, 64 increasing their positions, 38 reducing their positions, and 15 closing their positions.

New
Increased
Maintained
Reduced
Closed

80% more first-time investments, than exits

New positions opened: 27 | Existing positions closed: 15

68% more repeat investments, than reductions

Existing positions increased: 64 | Existing positions reduced: 38

45% more capital invested

Capital invested by funds: $739M → $1.07B (+$331M)

33% more funds holding in top 10

Funds holding in top 10: 34 (+1)

13.7% more ownership

Funds ownership: 91.29%104.99% (+14%)

8% more funds holding

Funds holding: 142153 (+11)

90% less call options, than puts

Call options by funds: $4.89M | Put options by funds: $50.7M

Holders
153
Holders Change
+11
Holders Change %
+7.75%
% of All Funds
2.01%
Holding in Top 10
4
Holding in Top 10 Change
+1
Holding in Top 10 Change %
+33.33%
% of All Funds
0.05%
New
27
Increased
64
Reduced
38
Closed
15
Calls
$4.89M
Puts
$50.7M
Net Calls
-$45.8M
Net Calls Change
-$7.34M
Name Holding Trade Value Shares
Change
Change in
Stake
Fidelity Investments
1
Fidelity Investments
Massachusetts
$153M +$68.5M +6,889,043 +112%
T. Rowe Price Investment Management
2
T. Rowe Price Investment Management
Maryland
$98.6M +$1.42M +142,906 +2%
BlackRock
3
BlackRock
New York
$68.2M +$518K +52,044 +0.9%
RG
4
Redmile Group
California
$58.8M +$1.5M +151,160 +3%
Vanguard Group
5
Vanguard Group
Pennsylvania
$57.3M +$3.67M +368,674 +8%
Point72 Asset Management
6
Point72 Asset Management
Connecticut
$56.5M +$1.38M +138,701 +3%
ES
7
Enavate Sciences
California
$55.8M
EC
8
EcoR1 Capital
California
$47.8M
T. Rowe Price Associates
9
T. Rowe Price Associates
Maryland
$43.8M +$7.57M +760,690 +26%
OM
10
Opaleye Management
Massachusetts
$37.3M -$3.43M -344,581 -10%
Primecap Management
11
Primecap Management
California
$35.3M -$21.9K -2,201 -0.1%
State Street
12
State Street
Massachusetts
$32.8M +$2.82M +283,057 +11%
JFG
13
Jefferies Financial Group
New York
$24.6M +$143K +14,340 +0.7%
Geode Capital Management
14
Geode Capital Management
Massachusetts
$22.2M +$338K +33,995 +2%
Morgan Stanley
15
Morgan Stanley
New York
$21.5M +$14.2M +1,429,461 +354%
RAM
16
Readystate Asset Management
Illinois
$15.4M -$351K -35,296 -3%
WP
17
Woodline Partners
California
$14.9M -$3.82M -383,934 -23%
Principal Financial Group
18
Principal Financial Group
Iowa
$12.9M +$7.58M +762,147 +222%
PCH
19
Polar Capital Holdings
United Kingdom
$12.4M +$585K +58,776 +6%
CM
20
Caption Management
Oklahoma
$12.2M +$10.4M +1,040,700 New
Toronto Dominion Bank
21
Toronto Dominion Bank
Ontario, Canada
$12.1M -$10.4M -1,049,644 -50%
CS
22
Candriam SCA
Luxembourg
$10.1M +$5.39M +541,441 +170%
Citadel Advisors
23
Citadel Advisors
Florida
$9.85M +$8.37M +841,138 New
Janus Henderson Group
24
Janus Henderson Group
United Kingdom
$8.94M -$2.76M -277,239 -27%
Northern Trust
25
Northern Trust
Illinois
$8.27M +$149K +14,958 +2%

IMNM Hedge Fund Activity: Q3 2025 in Review

153 of the 7,620 institutional investors tracked by Wall St. Rank reported a position in Immunome (IMNM) for Q3 2025, worth a combined $1.07B — up 45% from $739M a quarter earlier.

Buyers outnumbered sellers: 27 funds opened new IMNM positions and 15 closed out — a net gain of 12 holders — while 64 added to existing stakes and 38 trimmed.

The largest buyer was Fidelity Investments, adding an estimated $68.5M. The largest seller was Toronto Dominion Bank, cutting an estimated $10.4M.

  • 153 institutional investors held Immunome (IMNM) as of Q3 2025, up from 142 in Q2 2025.
  • Funds reported $1.07B of Immunome stock for Q3 2025, up 45% quarter-over-quarter.
  • 27 funds opened new Immunome positions in Q3 2025 and 15 closed out, a net change of +12 holders.
  • The largest Immunome buyer in Q3 2025 was Fidelity Investments, an estimated $68.5M added.
  • The largest Immunome seller in Q3 2025 was Toronto Dominion Bank, an estimated $10.4M sold.

Based on aggregated 13F filings for Q3 2025.