|
1
|
Franklin Resources
San Mateo,
California
|
$101M
|
-$789K
|
-50,280
|
-0.6%
|
|
|
2
|
Tang Capital Management
San Diego,
California
|
$81.2M
|
–
|
–
|
–
|
|
|
3
|
Fidelity Investments
Boston,
Massachusetts
|
$76.9M
|
+$322K
|
+20,545
|
+0.4%
|
|
|
4
|
Janus Henderson Investors US
Denver,
Colorado
|
$59.9M
|
+$8.5M
|
+542,007
|
+13%
|
|
|
5
|
Broadfin Capital
New York
|
$51.1M
|
+$16.5M
|
+1,049,587
|
+37%
|
|
|
6
|
Kingdon Capital Management
New York
|
$36.9M
|
+$1.84M
|
+117,164
|
+4%
|
|
|
7
|
PFM Health Sciences
San Francisco,
California
|
$35.8M
|
-$10.3M
|
-656,975
|
-19%
|
|
|
8
|
Baker Bros. Advisors
New York
|
$31.2M
|
-$7.43M
|
-473,681
|
-17%
|
|
|
9
|
Cormorant Asset Management
Boston,
Massachusetts
|
$25.6M
|
+$2.82M
|
+180,000
|
+10%
|
|
|
10
|
Highland Capital Management (Texas)
Dallas,
Texas
|
$20.5M
|
+$14.3M
|
+912,086
|
+140%
|
|
|
11
|
State Street
Boston,
Massachusetts
|
$17.9M
|
+$4.24M
|
+270,022
|
+25%
|
|
|
12
|
Vanguard Group
Malvern,
Pennsylvania
|
$17.5M
|
+$417K
|
+26,560
|
+2%
|
|
|
13
|
|
$14.4M
|
–
|
–
|
–
|
|
|
14
|
BlackRock Fund Advisors
San Francisco,
California
|
$13.4M
|
+$2.22M
|
+141,735
|
+16%
|
|
|
15
|
BlackRock Institutional Trust
San Francisco,
California
|
$10.9M
|
+$11.7K
|
+748
|
+0.1%
|
|
|
16
|
|
$7.67M
|
-$34.3M
|
-2,187,837
|
-79%
|
|
|
17
|
Rubric Capital Management (New York)
New York
|
$7.21M
|
+$8.63M
|
+550,000
|
New
|
|
|
18
|
Alyeska Investment Group
Chicago,
Illinois
|
$6.86M
|
+$5.13M
|
+327,255
|
+167%
|
|
|
19
|
Susquehanna International Group
Bala Cynwyd,
Pennsylvania
|
$6.37M
|
+$5.04M
|
+321,445
|
+195%
|
|
|
20
|
Royal Bank of Canada
Toronto,
Ontario, Canada
|
$5.4M
|
-$85.3K
|
-5,439
|
-1%
|
|
|
21
|
VHCP Management II
New York
|
$5.32M
|
–
|
–
|
–
|
|
|
22
|
Northern Trust
Chicago,
Illinois
|
$4.8M
|
+$132K
|
+8,420
|
+2%
|
|
|
23
|
Panagora Asset Management
Boston,
Massachusetts
|
$3.59M
|
+$1.13M
|
+72,316
|
+36%
|
|
|
24
|
Geode Capital Management
Boston,
Massachusetts
|
$3.46M
|
+$149K
|
+9,518
|
+4%
|
|
|
25
|
Millennium Management
New York
|
$3.37M
|
+$4.03M
|
+257,062
|
New
|
|
